FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2108463924> ?p ?o ?g. }

• W2108463924 endingPage "88" @default.
• W2108463924 startingPage "83" @default.
• W2108463924 abstract "Proteolytic enzymes released from granulocytes upon stimulation with the chemotactic N-formyl peptide FNLPNTL (in the presence of cytochalasin B) prevented activation of tumor cell single-chain urokinase-type plasminogen activator (pro-uPA) by plasmin. Elastase was identified by the use of eglin C (elastase inhibitor) and a monoclonal antibody to elastase as the functional proteolytic enzyme in granulocyte supernatants. Action of purified granulocyte elastase on pro-uPA generated enzymatically inactive two-chain uPA linked by disulfide bridges which was indistinguishable by SDS-PAGE from plasmin-generated HMW-uPA. The major elastase cleavage site in pro-uPA was located between Ile159 and Ile160. a minor one between Thr165 and Thr166. Elastase cannot substitute for plasmin in the proteolytic activation of pro-uPA to enzymatically active HMW-uPA. However, when pro-uPA was first activated by plasmin to form enzymatically active HMW-uPA, this enzymatic activity was not impaired by subsequent elastase treatment." @default.
• W2108463924 created "2016-06-24" @default.
• W2108463924 creator A5009333740 @default.
• W2108463924 creator A5018959739 @default.
• W2108463924 creator A5023638355 @default.
• W2108463924 creator A5041477797 @default.
• W2108463924 creator A5047836442 @default.
• W2108463924 creator A5060041696 @default.
• W2108463924 creator A5073443528 @default.
• W2108463924 creator A5076312725 @default.
• W2108463924 date "1989-09-11" @default.
• W2108463924 modified "2023-09-23" @default.
• W2108463924 title "Elastase released from human granulocytes stimulated withN-formyl-chemotactic peptide prevents activation of tumor cell prourokinase (pro-uPA)" @default.
• W2108463924 cites W1493910160 @default.
• W2108463924 cites W1963621811 @default.
• W2108463924 cites W1974148619 @default.
• W2108463924 cites W1977199745 @default.
• W2108463924 cites W1987317575 @default.
• W2108463924 cites W2039573204 @default.
• W2108463924 cites W2050556701 @default.
• W2108463924 cites W2072137974 @default.
• W2108463924 cites W2100837269 @default.
• W2108463924 cites W23122061 @default.
• W2108463924 cites W2313302841 @default.
• W2108463924 cites W2414230784 @default.
• W2108463924 cites W323597899 @default.
• W2108463924 cites W4238856854 @default.
• W2108463924 cites W2072796605 @default.
• W2108463924 doi "https://doi.org/10.1016/0014-5793(89)81065-8" @default.
• W2108463924 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2529137" @default.
• W2108463924 hasPublicationYear "1989" @default.
• W2108463924 type Work @default.
• W2108463924 sameAs 2108463924 @default.
• W2108463924 citedByCount "30" @default.
• W2108463924 countsByYear W21084639242020 @default.
• W2108463924 crossrefType "journal-article" @default.
• W2108463924 hasAuthorship W2108463924A5009333740 @default.
• W2108463924 hasAuthorship W2108463924A5018959739 @default.
• W2108463924 hasAuthorship W2108463924A5023638355 @default.
• W2108463924 hasAuthorship W2108463924A5041477797 @default.
• W2108463924 hasAuthorship W2108463924A5047836442 @default.
• W2108463924 hasAuthorship W2108463924A5060041696 @default.
• W2108463924 hasAuthorship W2108463924A5073443528 @default.
• W2108463924 hasAuthorship W2108463924A5076312725 @default.
• W2108463924 hasBestOaLocation W21084639241 @default.
• W2108463924 hasConcept C134018914 @default.
• W2108463924 hasConcept C153911025 @default.
• W2108463924 hasConcept C170493617 @default.
• W2108463924 hasConcept C181199279 @default.
• W2108463924 hasConcept C185592680 @default.
• W2108463924 hasConcept C203014093 @default.
• W2108463924 hasConcept C2776326425 @default.
• W2108463924 hasConcept C2776892390 @default.
• W2108463924 hasConcept C2777983669 @default.
• W2108463924 hasConcept C2779679481 @default.
• W2108463924 hasConcept C2781044401 @default.
• W2108463924 hasConcept C2781071845 @default.
• W2108463924 hasConcept C3019223276 @default.
• W2108463924 hasConcept C54166955 @default.
• W2108463924 hasConcept C54355233 @default.
• W2108463924 hasConcept C55493867 @default.
• W2108463924 hasConcept C86803240 @default.
• W2108463924 hasConceptScore W2108463924C134018914 @default.
• W2108463924 hasConceptScore W2108463924C153911025 @default.
• W2108463924 hasConceptScore W2108463924C170493617 @default.
• W2108463924 hasConceptScore W2108463924C181199279 @default.
• W2108463924 hasConceptScore W2108463924C185592680 @default.
• W2108463924 hasConceptScore W2108463924C203014093 @default.
• W2108463924 hasConceptScore W2108463924C2776326425 @default.
• W2108463924 hasConceptScore W2108463924C2776892390 @default.
• W2108463924 hasConceptScore W2108463924C2777983669 @default.
• W2108463924 hasConceptScore W2108463924C2779679481 @default.
• W2108463924 hasConceptScore W2108463924C2781044401 @default.
• W2108463924 hasConceptScore W2108463924C2781071845 @default.
• W2108463924 hasConceptScore W2108463924C3019223276 @default.
• W2108463924 hasConceptScore W2108463924C54166955 @default.
• W2108463924 hasConceptScore W2108463924C54355233 @default.
• W2108463924 hasConceptScore W2108463924C55493867 @default.
• W2108463924 hasConceptScore W2108463924C86803240 @default.
• W2108463924 hasIssue "1" @default.
• W2108463924 hasLocation W21084639241 @default.
• W2108463924 hasLocation W21084639242 @default.
• W2108463924 hasOpenAccess W2108463924 @default.
• W2108463924 hasPrimaryLocation W21084639241 @default.
• W2108463924 hasRelatedWork W1509912507 @default.
• W2108463924 hasRelatedWork W172243739 @default.
• W2108463924 hasRelatedWork W1970368997 @default.
• W2108463924 hasRelatedWork W1992400548 @default.
• W2108463924 hasRelatedWork W202253331 @default.
• W2108463924 hasRelatedWork W2044949296 @default.
• W2108463924 hasRelatedWork W2108463924 @default.
• W2108463924 hasRelatedWork W2536967297 @default.
• W2108463924 hasRelatedWork W25775503 @default.
• W2108463924 hasRelatedWork W4235390561 @default.
• W2108463924 hasVolume "255" @default.
• W2108463924 isParatext "false" @default.
• W2108463924 isRetracted "false" @default.
• W2108463924 magId "2108463924" @default.

• next