FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2108465087> ?p ?o ?g. }

• W2108465087 endingPage "167" @default.
• W2108465087 startingPage "157" @default.
• W2108465087 abstract "Abstract Postendosymbiotic evolution has given rise to proteins that are multiply targeted within the cell. Various mechanisms have been identified to permit the expression of proteins encoding distinct N termini from a single gene. One mechanism involves alternative translation initiation (aTI). We previously showed evidence of aTI activity within the Arabidopsis thaliana organellar DNA polymerase gene POLγ2. Translation initiates at four distinct sites within this gene, two non-AUG, to produce distinct plastid and mitochondrially targeted forms of the protein. To understand the regulation of aTI in higher plants, we used Polγ2 as a model to investigate both cis- and trans-acting features of the process. Here, we show that aTI in Polγ2 and other plant genes involves ribosome scanning dependent on sequence context at the multiple initiation sites to condition specific binding of at least one trans-acting factor essential for site recognition. Multiple active translation initiation sites appear to operate in several plant genes, often to expand protein targeting. In plants, where the mitochondrion and plastid must share a considerable portion of their proteomes and coordinate their functions, leaky ribosome scanning behavior provides adaptive advantage in the evolution of protein dual targeting and translational regulation." @default.
• W2108465087 created "2016-06-24" @default.
• W2108465087 creator A5019859571 @default.
• W2108465087 creator A5040104968 @default.
• W2108465087 creator A5046913071 @default.
• W2108465087 creator A5047046584 @default.
• W2108465087 creator A5057676719 @default.
• W2108465087 creator A5062307665 @default.
• W2108465087 date "2009-01-01" @default.
• W2108465087 modified "2023-09-26" @default.
• W2108465087 title "Participation of Leaky Ribosome Scanning in Protein Dual Targeting by Alternative Translation Initiation in Higher Plants " @default.
• W2108465087 cites W1779959085 @default.
• W2108465087 cites W1969314942 @default.
• W2108465087 cites W1970259819 @default.
• W2108465087 cites W1975085160 @default.
• W2108465087 cites W1978885095 @default.
• W2108465087 cites W1982980697 @default.
• W2108465087 cites W1994244877 @default.
• W2108465087 cites W2035881772 @default.
• W2108465087 cites W2038335468 @default.
• W2108465087 cites W2044977183 @default.
• W2108465087 cites W2045348184 @default.
• W2108465087 cites W2061060697 @default.
• W2108465087 cites W2065234142 @default.
• W2108465087 cites W2066182414 @default.
• W2108465087 cites W2080469947 @default.
• W2108465087 cites W2089047063 @default.
• W2108465087 cites W2095438551 @default.
• W2108465087 cites W2109561892 @default.
• W2108465087 cites W2116122104 @default.
• W2108465087 cites W2116817481 @default.
• W2108465087 cites W2118499060 @default.
• W2108465087 cites W2118782857 @default.
• W2108465087 cites W2121359567 @default.
• W2108465087 cites W2134711222 @default.
• W2108465087 cites W2144056322 @default.
• W2108465087 cites W2144362290 @default.
• W2108465087 cites W2158645388 @default.
• W2108465087 doi "https://doi.org/10.1105/tpc.108.063644" @default.
• W2108465087 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2648075" @default.
• W2108465087 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19182105" @default.
• W2108465087 hasPublicationYear "2009" @default.
• W2108465087 type Work @default.
• W2108465087 sameAs 2108465087 @default.
• W2108465087 citedByCount "54" @default.
• W2108465087 countsByYear W21084650872012 @default.
• W2108465087 countsByYear W21084650872013 @default.
• W2108465087 countsByYear W21084650872014 @default.
• W2108465087 countsByYear W21084650872015 @default.
• W2108465087 countsByYear W21084650872016 @default.
• W2108465087 countsByYear W21084650872017 @default.
• W2108465087 countsByYear W21084650872018 @default.
• W2108465087 countsByYear W21084650872019 @default.
• W2108465087 countsByYear W21084650872020 @default.
• W2108465087 countsByYear W21084650872021 @default.
• W2108465087 countsByYear W21084650872022 @default.
• W2108465087 countsByYear W21084650872023 @default.
• W2108465087 crossrefType "journal-article" @default.
• W2108465087 hasAuthorship W2108465087A5019859571 @default.
• W2108465087 hasAuthorship W2108465087A5040104968 @default.
• W2108465087 hasAuthorship W2108465087A5046913071 @default.
• W2108465087 hasAuthorship W2108465087A5047046584 @default.
• W2108465087 hasAuthorship W2108465087A5057676719 @default.
• W2108465087 hasAuthorship W2108465087A5062307665 @default.
• W2108465087 hasBestOaLocation W21084650871 @default.
• W2108465087 hasConcept C104317684 @default.
• W2108465087 hasConcept C105580179 @default.
• W2108465087 hasConcept C149364088 @default.
• W2108465087 hasConcept C4718897 @default.
• W2108465087 hasConcept C54355233 @default.
• W2108465087 hasConcept C67705224 @default.
• W2108465087 hasConcept C69305403 @default.
• W2108465087 hasConcept C70721500 @default.
• W2108465087 hasConcept C86803240 @default.
• W2108465087 hasConcept C88478588 @default.
• W2108465087 hasConcept C93829228 @default.
• W2108465087 hasConcept C95444343 @default.
• W2108465087 hasConceptScore W2108465087C104317684 @default.
• W2108465087 hasConceptScore W2108465087C105580179 @default.
• W2108465087 hasConceptScore W2108465087C149364088 @default.
• W2108465087 hasConceptScore W2108465087C4718897 @default.
• W2108465087 hasConceptScore W2108465087C54355233 @default.
• W2108465087 hasConceptScore W2108465087C67705224 @default.
• W2108465087 hasConceptScore W2108465087C69305403 @default.
• W2108465087 hasConceptScore W2108465087C70721500 @default.
• W2108465087 hasConceptScore W2108465087C86803240 @default.
• W2108465087 hasConceptScore W2108465087C88478588 @default.
• W2108465087 hasConceptScore W2108465087C93829228 @default.
• W2108465087 hasConceptScore W2108465087C95444343 @default.
• W2108465087 hasIssue "1" @default.
• W2108465087 hasLocation W21084650871 @default.
• W2108465087 hasLocation W21084650872 @default.
• W2108465087 hasLocation W21084650873 @default.
• W2108465087 hasLocation W21084650874 @default.
• W2108465087 hasOpenAccess W2108465087 @default.
• W2108465087 hasPrimaryLocation W21084650871 @default.
• W2108465087 hasRelatedWork W1485108760 @default.
• W2108465087 hasRelatedWork W2050171717 @default.

• next