FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2108479568> ?p ?o ?g. }

• W2108479568 endingPage "858" @default.
• W2108479568 startingPage "851" @default.
• W2108479568 abstract "To compare the dose and volume of bladder and rectum treated using high-dose-rate (HDR) prostate implant boost versus conformal external beam radiotherapy boost, and to use the dose-volume information to perform a critical volume tolerance (CVT) analysis and then estimate the potential for further dose escalation using HDR brachytherapy boost.Using CT scan data collected before and after patients underwent HDR prostate implant, a 7-field conformal prostate-only external beam treatment plan and HDR brachytherapy treatment plan were constructed for each patient. Doses to the normal structures were calculated. Dose-volume histograms (DVH) were plotted for comparison of the two techniques. Wilcoxon signed rank test was performed at four dose levels to compare the dose to normal structures between the two treatment techniques. The acute and late effects of HDR brachytherapy were calculated based on the linear-quadratic (LQ) model. CVT analyses were performed to calculate the potential dose gain (PDG) using HDR brachytherapy boost.The volume of bladder and rectum receiving high dose was significantly less from implant boost. On the average, 0.19 cc of the bladder received 100% of the brachytherapy prescription dose, compared with 5.1 cc of the bladder receiving 100% of the prescription dose in the 7-field conformal external beam radiotherapy boost. Similarly, 0.25 cc of the rectum received 100% of the dose with the implant boost, as compared to 2.9 cc in the conformal external beam treatment. The implant also delivered higher doses inside the prostate volume. On average, 47% of the prostate received > or =150% of the prescription dose. The CVT analysis revealed a range of PDG using the HDR brachytherapy boost which depended on the following variables: critical volume (CV), critical volume tolerance dose (CVTD), number of HDR fractions (N), and the dose of external beam radiotherapy (XRT) delivered with brachytherapy boost. The PDG varied from -3.45% to 10.53% for tumor with an alpha-beta ratio of 10 and 7.14% to 64.6% for tumor with an alpha-beta ratio of 1.5 based on the parameters used for calculation in this study.HDR brachytherapy can provide better sparing of rectum and bladder while delivering a higher dose to the prostate. Even with the increased late effects of high dose per fraction, there is still a potential for dose escalation beyond external radiotherapy limits using HDR brachytherapy." @default.
• W2108479568 created "2016-06-24" @default.
• W2108479568 creator A5021162147 @default.
• W2108479568 creator A5022388474 @default.
• W2108479568 creator A5036083907 @default.
• W2108479568 creator A5042728664 @default.
• W2108479568 creator A5073984522 @default.
• W2108479568 creator A5089472018 @default.
• W2108479568 date "2000-03-01" @default.
• W2108479568 modified "2023-10-17" @default.
• W2108479568 title "Normal tissue dosimetric comparison between hdr prostate implant boost and conformal external beam radiotherapy boost: potential for dose escalation" @default.
• W2108479568 cites W1966226622 @default.
• W2108479568 cites W1993777632 @default.
• W2108479568 cites W2009301622 @default.
• W2108479568 cites W2020637833 @default.
• W2108479568 cites W2026361718 @default.
• W2108479568 cites W2053705002 @default.
• W2108479568 cites W2063266750 @default.
• W2108479568 cites W2065840363 @default.
• W2108479568 cites W2090257225 @default.
• W2108479568 cites W2099909650 @default.
• W2108479568 cites W2104631398 @default.
• W2108479568 cites W2158843739 @default.
• W2108479568 cites W2159677793 @default.
• W2108479568 doi "https://doi.org/10.1016/s0360-3016(99)00501-5" @default.
• W2108479568 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10705005" @default.
• W2108479568 hasPublicationYear "2000" @default.
• W2108479568 type Work @default.
• W2108479568 sameAs 2108479568 @default.
• W2108479568 citedByCount "54" @default.
• W2108479568 countsByYear W21084795682012 @default.
• W2108479568 countsByYear W21084795682013 @default.
• W2108479568 countsByYear W21084795682014 @default.
• W2108479568 countsByYear W21084795682016 @default.
• W2108479568 countsByYear W21084795682018 @default.
• W2108479568 countsByYear W21084795682021 @default.
• W2108479568 countsByYear W21084795682022 @default.
• W2108479568 crossrefType "journal-article" @default.
• W2108479568 hasAuthorship W2108479568A5021162147 @default.
• W2108479568 hasAuthorship W2108479568A5022388474 @default.
• W2108479568 hasAuthorship W2108479568A5036083907 @default.
• W2108479568 hasAuthorship W2108479568A5042728664 @default.
• W2108479568 hasAuthorship W2108479568A5073984522 @default.
• W2108479568 hasAuthorship W2108479568A5089472018 @default.
• W2108479568 hasConcept C121608353 @default.
• W2108479568 hasConcept C126322002 @default.
• W2108479568 hasConcept C126838900 @default.
• W2108479568 hasConcept C141071460 @default.
• W2108479568 hasConcept C201645570 @default.
• W2108479568 hasConcept C2775908122 @default.
• W2108479568 hasConcept C2776235491 @default.
• W2108479568 hasConcept C2777416452 @default.
• W2108479568 hasConcept C2780198649 @default.
• W2108479568 hasConcept C2781074409 @default.
• W2108479568 hasConcept C2781411149 @default.
• W2108479568 hasConcept C2989005 @default.
• W2108479568 hasConcept C509974204 @default.
• W2108479568 hasConcept C71924100 @default.
• W2108479568 hasConcept C75088862 @default.
• W2108479568 hasConceptScore W2108479568C121608353 @default.
• W2108479568 hasConceptScore W2108479568C126322002 @default.
• W2108479568 hasConceptScore W2108479568C126838900 @default.
• W2108479568 hasConceptScore W2108479568C141071460 @default.
• W2108479568 hasConceptScore W2108479568C201645570 @default.
• W2108479568 hasConceptScore W2108479568C2775908122 @default.
• W2108479568 hasConceptScore W2108479568C2776235491 @default.
• W2108479568 hasConceptScore W2108479568C2777416452 @default.
• W2108479568 hasConceptScore W2108479568C2780198649 @default.
• W2108479568 hasConceptScore W2108479568C2781074409 @default.
• W2108479568 hasConceptScore W2108479568C2781411149 @default.
• W2108479568 hasConceptScore W2108479568C2989005 @default.
• W2108479568 hasConceptScore W2108479568C509974204 @default.
• W2108479568 hasConceptScore W2108479568C71924100 @default.
• W2108479568 hasConceptScore W2108479568C75088862 @default.
• W2108479568 hasIssue "4" @default.
• W2108479568 hasLocation W21084795681 @default.
• W2108479568 hasLocation W21084795682 @default.
• W2108479568 hasOpenAccess W2108479568 @default.
• W2108479568 hasPrimaryLocation W21084795681 @default.
• W2108479568 hasRelatedWork W1523662141 @default.
• W2108479568 hasRelatedWork W1948904854 @default.
• W2108479568 hasRelatedWork W1971464107 @default.
• W2108479568 hasRelatedWork W1995528350 @default.
• W2108479568 hasRelatedWork W2170013535 @default.
• W2108479568 hasRelatedWork W2587567312 @default.
• W2108479568 hasRelatedWork W2909534040 @default.
• W2108479568 hasRelatedWork W3030956247 @default.
• W2108479568 hasRelatedWork W3031850683 @default.
• W2108479568 hasRelatedWork W2413227250 @default.
• W2108479568 hasVolume "46" @default.
• W2108479568 isParatext "false" @default.
• W2108479568 isRetracted "false" @default.
• W2108479568 magId "2108479568" @default.
• W2108479568 workType "article" @default.