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- W2108495559 abstract "SUMMARY This management perspective briefly covers the histology and molecular features of lobular in situ neoplasia and provides an in-depth discussion of the need for surgical excision if lobular in situ neoplasia is diagnosed on core-needle biopsy. The management of lobular in situ neoplasia found on core-needle biopsy has been an area of recent study with varying results. Emerging data suggest that low-risk patients with a limited extent of isolated classic lobular in situ neoplasia found on core-needle biopsy may not require subsequent surgical excision. However, high-risk patients, those with extensive lobular in situ neoplasia, or other high-risk lesions noted on core-needle biopsy likely benefit from surgical excision. Most authors recommend surgical excision when pleomorphic lobular carcinoma in situ is found on core-needle biopsy due to its higher association with invasive carcinoma. However, the natural history of this more recently described variant of lobular carcinoma in situ is not fully de..." @default.
- W2108495559 created "2016-06-24" @default.
- W2108495559 creator A5043710182 @default.
- W2108495559 date "2014-03-01" @default.
- W2108495559 modified "2023-10-16" @default.
- W2108495559 title "When is excision necessary for atypical lobular hyperplasia and lobular carcinoma in situ?" @default.
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- W2108495559 doi "https://doi.org/10.2217/bmt.13.78" @default.
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