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• W2108504044 abstract "Abstract Background The aim of this study was to determine whether plasma hydrogen sulfide (H 2 S) is a biomarker for predicting coronary artery lesions (CAL) in children with Kawasaki disease (KD). Methods A prospective study was conducted on 50 KD patients and 27 healthy children. Plasma H 2 S was analyzed at the acute stage. Plasma H 2 S was detected using the sensitive electrode method, and receiver operating characteristic curve (ROC) analysis was carried out. Results Plasma H 2 S in KD patients at the acute stage was significantly lower than that of controls. CAL patients had reduced plasma H 2 S at acute stage compared with the non‐CAL patients. A plasma H 2 S cut‐off of 31.2 µmol/L provided a sensitivity of 81% and a specificity of 62.5% for predicting coronary injuries in KD. Optimal specificity and sensitivity were obtained when using plasma H 2 S to predict CAL in KD children. Conclusion Plasma H 2 S level in the acute period is a potentially useful biomarker for predicting CAL in KD children." @default.
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• W2108504044 date "2015-05-29" @default.
• W2108504044 modified "2023-10-03" @default.
• W2108504044 title "Plasma H₂ S predicts coronary artery lesions in children with Kawasaki disease" @default.
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• W2108504044 doi "https://doi.org/10.1111/ped.12631" @default.
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