FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2108518323> ?p ?o ?g. }

• W2108518323 endingPage "11797" @default.
• W2108518323 startingPage "11790" @default.
• W2108518323 abstract "How alphaherpesvirus capsids acquire tegument proteins remains a key question in viral assembly. Using pseudorabies virus (PRV), we have previously shown that the 62 carboxy-terminal amino acids of the VP1/2 large tegument protein are essential for viral propagation and when transiently expressed as a fusion to green fluorescent protein relocalize to nuclear capsid assemblons following viral infection. Here, we show that localization of the VP1/2 capsid-binding domain (VP1/2cbd) into assemblons is conserved in herpes simplex virus type 1 (HSV-1) and that this recruitment is specifically on capsids. Using a mutant virus screen, we find that the protein product of the UL25 gene is essential for VP1/2cbd association with capsids. An interaction between UL25 and VP1/2 was corroborated by coimmunoprecipitation from cells transiently expressing either HSV-1 or PRV proteins. Taken together, these findings suggest that the essential function of the VP1/2 carboxy terminus is to anchor the VP1/2 tegument protein to capsids. Furthermore, UL25 encodes a multifunctional capsid protein involved in not only encapsidation, as previously described, but also tegumentation." @default.
• W2108518323 created "2016-06-24" @default.
• W2108518323 creator A5011427445 @default.
• W2108518323 creator A5042613756 @default.
• W2108518323 creator A5067763422 @default.
• W2108518323 creator A5068215400 @default.
• W2108518323 date "2007-11-01" @default.
• W2108518323 modified "2023-10-10" @default.
• W2108518323 title "The Capsid and Tegument of the Alphaherpesviruses Are Linked by an Interaction between the UL25 and VP1/2 Proteins" @default.
• W2108518323 cites W1541539119 @default.
• W2108518323 cites W1638971122 @default.
• W2108518323 cites W1644007388 @default.
• W2108518323 cites W1907539319 @default.
• W2108518323 cites W1964419190 @default.
• W2108518323 cites W1969548298 @default.
• W2108518323 cites W1975285829 @default.
• W2108518323 cites W1988736583 @default.
• W2108518323 cites W1994882633 @default.
• W2108518323 cites W1999985873 @default.
• W2108518323 cites W2000290494 @default.
• W2108518323 cites W2010202707 @default.
• W2108518323 cites W2017969950 @default.
• W2108518323 cites W2020341083 @default.
• W2108518323 cites W2027929104 @default.
• W2108518323 cites W2028321028 @default.
• W2108518323 cites W2030434282 @default.
• W2108518323 cites W2036839993 @default.
• W2108518323 cites W2037933581 @default.
• W2108518323 cites W2049587364 @default.
• W2108518323 cites W2051221600 @default.
• W2108518323 cites W2052319008 @default.
• W2108518323 cites W2058419113 @default.
• W2108518323 cites W2065187385 @default.
• W2108518323 cites W2079133515 @default.
• W2108518323 cites W2081460107 @default.
• W2108518323 cites W2089302260 @default.
• W2108518323 cites W2093542233 @default.
• W2108518323 cites W2095952187 @default.
• W2108518323 cites W2101228358 @default.
• W2108518323 cites W2103125422 @default.
• W2108518323 cites W2103246049 @default.
• W2108518323 cites W2106137972 @default.
• W2108518323 cites W2106377164 @default.
• W2108518323 cites W2107119800 @default.
• W2108518323 cites W2113039620 @default.
• W2108518323 cites W2115734610 @default.
• W2108518323 cites W2116633863 @default.
• W2108518323 cites W2119613970 @default.
• W2108518323 cites W2119628359 @default.
• W2108518323 cites W2121651754 @default.
• W2108518323 cites W2123837005 @default.
• W2108518323 cites W2125421787 @default.
• W2108518323 cites W2129542883 @default.
• W2108518323 cites W2132223883 @default.
• W2108518323 cites W2135316549 @default.
• W2108518323 cites W2136242594 @default.
• W2108518323 cites W2138395245 @default.
• W2108518323 cites W2140377668 @default.
• W2108518323 cites W2142404794 @default.
• W2108518323 cites W2147881941 @default.
• W2108518323 cites W2149370561 @default.
• W2108518323 cites W2150063226 @default.
• W2108518323 cites W2151214607 @default.
• W2108518323 cites W2157746371 @default.
• W2108518323 cites W2158067882 @default.
• W2108518323 cites W2159292028 @default.
• W2108518323 cites W2165155404 @default.
• W2108518323 cites W2165246104 @default.
• W2108518323 cites W2167366971 @default.
• W2108518323 cites W2417786818 @default.
• W2108518323 doi "https://doi.org/10.1128/jvi.01113-07" @default.
• W2108518323 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2168758" @default.
• W2108518323 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17715218" @default.
• W2108518323 hasPublicationYear "2007" @default.
• W2108518323 type Work @default.
• W2108518323 sameAs 2108518323 @default.
• W2108518323 citedByCount "126" @default.
• W2108518323 countsByYear W21085183232012 @default.
• W2108518323 countsByYear W21085183232013 @default.
• W2108518323 countsByYear W21085183232014 @default.
• W2108518323 countsByYear W21085183232015 @default.
• W2108518323 countsByYear W21085183232016 @default.
• W2108518323 countsByYear W21085183232017 @default.
• W2108518323 countsByYear W21085183232018 @default.
• W2108518323 countsByYear W21085183232019 @default.
• W2108518323 countsByYear W21085183232020 @default.
• W2108518323 countsByYear W21085183232021 @default.
• W2108518323 countsByYear W21085183232022 @default.
• W2108518323 countsByYear W21085183232023 @default.
• W2108518323 crossrefType "journal-article" @default.
• W2108518323 hasAuthorship W2108518323A5011427445 @default.
• W2108518323 hasAuthorship W2108518323A5042613756 @default.
• W2108518323 hasAuthorship W2108518323A5067763422 @default.
• W2108518323 hasAuthorship W2108518323A5068215400 @default.
• W2108518323 hasBestOaLocation W21085183231 @default.
• W2108518323 hasConcept C104317684 @default.
• W2108518323 hasConcept C123894998 @default.
• W2108518323 hasConcept C140704245 @default.

• next