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- W2108533225 abstract "Abstract Aim: To describe clinical signs associated with Human Astrovirus (HAstV) in stools in neonatal units. Methods: During 2005–2006, all stool virology performed for isolated digestive symptoms or suspicion of neonatal infection was tested for HAstV by an amplified enzyme‐linked immunoassay (IDEIA™ Astrovirus test, Dako Cytomation). Each newborn with a positive result (HAstV+ group) was retrospectively matched with the first following symptomatic newborn in the same care unit having a negative stool virology (HAstV− group). Clinical data were collected during two 3‐day periods (just after faecal samples collection and 1 week before) and compared within and between each group. Results: Human astrovirus was detected in faeces of 68 newborns [gestational age: 31.4(28.8–34) weeks] at a post‐natal age of 23 (15–42) days without seasonal dominance. Human astrovirus+ and HAstV− groups were comparable. Bloody stool (54.4% versus 14.7%, p < 0.01) and stage II–III necrotizing enterocolitis (20.6% versus 4.4%, p < 0.05) were more frequently observed in HAstV+ than in HAstV− group; these associations were confirmed by logistic regression analysis. Conclusion: This descriptive study argues for a possible association between HAstV and digestive symptoms in newborns specifically in preterm infants." @default.
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- W2108533225 date "2012-01-10" @default.
- W2108533225 modified "2023-10-18" @default.
- W2108533225 title "Astrovirus and digestive disorders in neonatal units" @default.
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- W2108533225 doi "https://doi.org/10.1111/j.1651-2227.2011.02569.x" @default.
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