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• W2108593669 abstract "In this study, high-fat diet-induced obese mice were administered oat soluble (SOG) and insoluble β-glucan (IOG) at different doses. Mice were sacrificed after 6 weeks, body weight, serum lipid level, fecal pH value, fecal bile acid excretion and total colonic short-chain fatty acid (SCFA) concentration was measured. Mesenteric adipocyte count and size were also evaluated histologically. The population of <i>Lactobacillus</i> in colon was determined. Compared with obese mice administered normal saline, body weight, serum cholesterol, triglycerides and the lipoprotein profile were significantly decreased (<i>p</i><0.05) in mice administered SOG and IOG. The fecal pH value was significantly decreased (<i>p</i><0.05), while both fecal bile acid excretion and total colonic SCFA concentration were significantly increased (<i>p</i><0.05). In addition, it exhibited an increase of fat cell count and a decrease of cell size. SOG and IOG restored the number of <i>Lactobacillus</i> in colon (<i>p</i><0.05). IOG was more effective on weight-loss while SOG might play a more important role in improving serum lipids and the efficacy of promoting growth of <i>Lactobacillus</i> is similar. A dosage of 2 g•kg<SUP>-1</SUP>•BW (Body Weight) produced the most significant effect. These data were anticipated to support the prebiotic property and anti-obesity effect of oat β-glucan." @default.
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• W2108593669 date "2014-08-12" @default.
• W2108593669 modified "2023-10-05" @default.
• W2108593669 title "Effect of Oat Soluble and Insoluble β-glucan on Lipid Metabolism and Intestinal<i> </i><i>Lactobacillus</i> in High-fat Diet-induced Obese Mice" @default.
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• W2108593669 doi "https://doi.org/10.12691/jfnr-2-8-13" @default.
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