FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2108596041> ?p ?o ?g. }

• W2108596041 endingPage "5211" @default.
• W2108596041 startingPage "5203" @default.
• W2108596041 abstract "This study aimed to explore the role of miR-339-5p in ovarian cancer. The expression of miR-339-5p in seven ovarian cancer cell lines (Hey, SKOV3, OVCAR5, SKOV3-IP, A2780, CAOV3, and OVCA433) was detected by quantitative real-time polymerase chain reaction (qRT-PCR). The miR-339-5p mimic and inhibitor were used to regulate its expression. Migration, invasion, and proliferation were examined. A bioinformatics analysis was used to predict targets, and a dual-luciferase reporter system was applied for validation, along with Western blot verification. Additionally, the association of miR-339-5p and its target genes with ovarian cancer was analyzed based on The Cancer Genome Atlas (TCGA) database. OVCAR5 and SKOV3 had the highest and lowest miR-339-5p expression, respectively. Inhibition of miR-339-5p expression increased the migration and invasion of OVCAR5 cells, while in SKOV3 cells, upregulated miR-339-5p attenuated the migration and invasion ability. Modulation of miR-339-5p had no effect on proliferation. The genes nucleus accumbens associated 1(BEN and BTB (POZ) domain containing) (NACC1) and B cell lymphoma-6 (bcl6) were validated to be targets of miR-339-5p. Clinically, patients with a high expression of NACC1 had a high risk in the survival analysis. miR-339-5p inhibits migration and invasion in ovarian cancer by targeting NACC1 and BCL6. miR-339-5p may be a biomarker of metastasis in ovarian cancer; NACC1 had a predictive value for ovarian cancer progression." @default.
• W2108596041 created "2016-06-24" @default.
• W2108596041 creator A5027835055 @default.
• W2108596041 creator A5063783123 @default.
• W2108596041 creator A5081451261 @default.
• W2108596041 creator A5081469956 @default.
• W2108596041 date "2015-11-09" @default.
• W2108596041 modified "2023-09-28" @default.
• W2108596041 title "miR-339-5p inhibits migration and invasion in ovarian cancer cell lines by targeting NACC1 and BCL6" @default.
• W2108596041 cites W144423133 @default.
• W2108596041 cites W1736089713 @default.
• W2108596041 cites W1767089461 @default.
• W2108596041 cites W1970993743 @default.
• W2108596041 cites W1976457549 @default.
• W2108596041 cites W1982502197 @default.
• W2108596041 cites W1983370435 @default.
• W2108596041 cites W1989467084 @default.
• W2108596041 cites W1994930186 @default.
• W2108596041 cites W2002037400 @default.
• W2108596041 cites W2005453082 @default.
• W2108596041 cites W2019829976 @default.
• W2108596041 cites W2020486699 @default.
• W2108596041 cites W2020829192 @default.
• W2108596041 cites W2021802737 @default.
• W2108596041 cites W2047529648 @default.
• W2108596041 cites W2051783089 @default.
• W2108596041 cites W2068767287 @default.
• W2108596041 cites W2088846648 @default.
• W2108596041 cites W2098434984 @default.
• W2108596041 cites W2103762288 @default.
• W2108596041 cites W2116521322 @default.
• W2108596041 cites W2118680637 @default.
• W2108596041 cites W2121107160 @default.
• W2108596041 cites W2126496132 @default.
• W2108596041 cites W2143017330 @default.
• W2108596041 cites W2148448730 @default.
• W2108596041 cites W2162811744 @default.
• W2108596041 cites W2167849637 @default.
• W2108596041 cites W2168784917 @default.
• W2108596041 cites W2276190994 @default.
• W2108596041 cites W4235085211 @default.
• W2108596041 cites W874642714 @default.
• W2108596041 doi "https://doi.org/10.1007/s13277-015-4390-2" @default.
• W2108596041 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26553360" @default.
• W2108596041 hasPublicationYear "2015" @default.
• W2108596041 type Work @default.
• W2108596041 sameAs 2108596041 @default.
• W2108596041 citedByCount "34" @default.
• W2108596041 countsByYear W21085960412016 @default.
• W2108596041 countsByYear W21085960412017 @default.
• W2108596041 countsByYear W21085960412018 @default.
• W2108596041 countsByYear W21085960412019 @default.
• W2108596041 countsByYear W21085960412020 @default.
• W2108596041 countsByYear W21085960412021 @default.
• W2108596041 countsByYear W21085960412022 @default.
• W2108596041 countsByYear W21085960412023 @default.
• W2108596041 crossrefType "journal-article" @default.
• W2108596041 hasAuthorship W2108596041A5027835055 @default.
• W2108596041 hasAuthorship W2108596041A5063783123 @default.
• W2108596041 hasAuthorship W2108596041A5081451261 @default.
• W2108596041 hasAuthorship W2108596041A5081469956 @default.
• W2108596041 hasConcept C121608353 @default.
• W2108596041 hasConcept C126322002 @default.
• W2108596041 hasConcept C143998085 @default.
• W2108596041 hasConcept C159654299 @default.
• W2108596041 hasConcept C203014093 @default.
• W2108596041 hasConcept C2777537477 @default.
• W2108596041 hasConcept C2778453870 @default.
• W2108596041 hasConcept C2780427987 @default.
• W2108596041 hasConcept C502942594 @default.
• W2108596041 hasConcept C71924100 @default.
• W2108596041 hasConcept C86803240 @default.
• W2108596041 hasConcept C96926380 @default.
• W2108596041 hasConceptScore W2108596041C121608353 @default.
• W2108596041 hasConceptScore W2108596041C126322002 @default.
• W2108596041 hasConceptScore W2108596041C143998085 @default.
• W2108596041 hasConceptScore W2108596041C159654299 @default.
• W2108596041 hasConceptScore W2108596041C203014093 @default.
• W2108596041 hasConceptScore W2108596041C2777537477 @default.
• W2108596041 hasConceptScore W2108596041C2778453870 @default.
• W2108596041 hasConceptScore W2108596041C2780427987 @default.
• W2108596041 hasConceptScore W2108596041C502942594 @default.
• W2108596041 hasConceptScore W2108596041C71924100 @default.
• W2108596041 hasConceptScore W2108596041C86803240 @default.
• W2108596041 hasConceptScore W2108596041C96926380 @default.
• W2108596041 hasIssue "4" @default.
• W2108596041 hasLocation W21085960411 @default.
• W2108596041 hasOpenAccess W2108596041 @default.
• W2108596041 hasPrimaryLocation W21085960411 @default.
• W2108596041 hasRelatedWork W2068614944 @default.
• W2108596041 hasRelatedWork W2259906034 @default.
• W2108596041 hasRelatedWork W2289272475 @default.
• W2108596041 hasRelatedWork W2295426530 @default.
• W2108596041 hasRelatedWork W2506002703 @default.
• W2108596041 hasRelatedWork W2533071622 @default.
• W2108596041 hasRelatedWork W2889687851 @default.
• W2108596041 hasRelatedWork W2922501427 @default.
• W2108596041 hasRelatedWork W3082795414 @default.

• next