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• W2108596512 endingPage "966" @default.
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• W2108596512 abstract "Mechanical ventilation is associated with morbidity in patients with brain injury.This study aims to assess the effectiveness of an extubation readiness bundle to decrease ventilator time in patients with brain injury.Before-after design in two intensive care units (ICUs) in one university hospital. Brain-injured patients ventilated more than 24 hours were evaluated during two phases (a 3-yr control phase followed by a 22-mo intervention phase). Bundle components were protective ventilation, early enteral nutrition, standardization of antibiotherapy for hospital-acquired pneumonia, and systematic approach to extubation. The primary endpoint was the duration of mechanical ventilation.A total of 299 and 200 patients, respectively, were analyzed in the control and the intervention phases of this before-after study. The intervention phase was associated with lower tidal volume (P < 0.01), higher positive end-expiratory pressure (P < 0.01), and higher enteral intake in the first 7 days (P = 0.01). The duration of mechanical ventilation was 14.9 ± 11.7 days in the control phase and 12.6 ± 10.3 days in the intervention phase (P = 0.02). The hazard ratio for extubation was 1.28 (95% confidence interval [CI], 1.04-1.57; P = 0.02) in the intervention phase. Adjusted hazard ratio was 1.40 (95% CI, 1.12-1.76; P < 0.01) in multivariate analysis and 1.34 (95% CI, 1.03-1.74; P = 0.02) in propensity score-adjusted analysis. ICU-free days at Day 90 increased from 50 ± 33 in the control phase to 57 ± 29 in the intervention phase (P < 0.01). Mortality at Day 90 was 28.4% in the control phase and 23.5% in the intervention phase (P = 0.22).The implementation of an evidence-based extubation readiness bundle was associated with a reduction in the duration of ventilation in patients with brain injury." @default.
• W2108596512 created "2016-06-24" @default.
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• W2108596512 date "2013-10-15" @default.
• W2108596512 modified "2023-10-18" @default.
• W2108596512 title "Implementation of an Evidence-based Extubation Readiness Bundle in 499 Brain-injured Patients. A Before–After Evaluation of a Quality Improvement Project" @default.
• W2108596512 cites W1852503640 @default.
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• W2108596512 cites W1966375310 @default.
• W2108596512 cites W1968853600 @default.
• W2108596512 cites W1972939711 @default.
• W2108596512 cites W1977283305 @default.
• W2108596512 cites W1989471045 @default.
• W2108596512 cites W1990934962 @default.
• W2108596512 cites W1994339957 @default.
• W2108596512 cites W1999160411 @default.
• W2108596512 cites W200845491 @default.
• W2108596512 cites W2010171380 @default.
• W2108596512 cites W2015378461 @default.
• W2108596512 cites W2017093758 @default.
• W2108596512 cites W2018656583 @default.
• W2108596512 cites W2025332003 @default.
• W2108596512 cites W2027076701 @default.
• W2108596512 cites W2028120889 @default.
• W2108596512 cites W2034186985 @default.
• W2108596512 cites W2036107593 @default.
• W2108596512 cites W2041468256 @default.
• W2108596512 cites W2044963616 @default.
• W2108596512 cites W2051063287 @default.
• W2108596512 cites W2051353898 @default.
• W2108596512 cites W2056793603 @default.
• W2108596512 cites W2062138171 @default.
• W2108596512 cites W2066970952 @default.
• W2108596512 cites W2074218333 @default.
• W2108596512 cites W2079648903 @default.
• W2108596512 cites W2089543004 @default.
• W2108596512 cites W2090406814 @default.
• W2108596512 cites W2099586690 @default.
• W2108596512 cites W2100757760 @default.
• W2108596512 cites W2102520835 @default.
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• W2108596512 cites W2116089402 @default.
• W2108596512 cites W2119472226 @default.
• W2108596512 cites W2121690051 @default.
• W2108596512 cites W2125699736 @default.
• W2108596512 cites W2131465096 @default.
• W2108596512 cites W2135672238 @default.
• W2108596512 cites W2137837217 @default.
• W2108596512 cites W2140066904 @default.
• W2108596512 cites W2145566510 @default.
• W2108596512 cites W2148706534 @default.
• W2108596512 cites W2149772433 @default.
• W2108596512 cites W2154746519 @default.
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• W2108596512 cites W2160722967 @default.
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• W2108596512 doi "https://doi.org/10.1164/rccm.201301-0116oc" @default.
• W2108596512 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23927561" @default.
• W2108596512 hasPublicationYear "2013" @default.
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