FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2108624984> ?p ?o ?g. }

• W2108624984 endingPage "1419" @default.
• W2108624984 startingPage "1411" @default.
• W2108624984 abstract "The mitotic spindle is a diamond-shaped molecular apparatus crucial for chromosomal segregation. The regulation of spindle length is well studied, but little is known about spindle width. Previous studies suggested that the spindle can self-organize to maintain a constant aspect ratio between its length and width against physical perturbations. Here we determine the widths of metaphase spindles of various sizes observed during embryogenesis in Caenorhabditis elegans, including small spindles obtained by knocking down the tpxl-1 or spd-2 gene. The spindle width correlates well with the spindle length, but the aspect ratio between the spindle length and spindle width is not constant, indicating an allometric relationship between these parameters. We characterize how DNA quantity (ploidy) affects spindle shape by using haploid and polyploid embryos. We find that the length of the hypotenuse, which corresponds to the distance from the apex of the metaphase plate to the spindle pole, remains constant in each cell stage, regardless of ploidy. On the basis of the quantitative data, we deduce an allometric equation that describes the spindle width as a function of the length of the hypotenuse and ploidy. On the basis of this equation, we propose a force-balance model to determine the spindle width." @default.
• W2108624984 created "2016-06-24" @default.
• W2108624984 creator A5045988991 @default.
• W2108624984 creator A5082585219 @default.
• W2108624984 date "2013-05-01" @default.
• W2108624984 modified "2023-10-12" @default.
• W2108624984 title "An allometric relationship between mitotic spindle width, spindle length, and ploidy in<i>Caenorhabditis elegans</i>embryos" @default.
• W2108624984 cites W1960872647 @default.
• W2108624984 cites W1972174678 @default.
• W2108624984 cites W1974546248 @default.
• W2108624984 cites W1977215201 @default.
• W2108624984 cites W19796932 @default.
• W2108624984 cites W1995841941 @default.
• W2108624984 cites W1995905083 @default.
• W2108624984 cites W1996152576 @default.
• W2108624984 cites W1996923295 @default.
• W2108624984 cites W2006117889 @default.
• W2108624984 cites W2006300227 @default.
• W2108624984 cites W2021944123 @default.
• W2108624984 cites W2028239476 @default.
• W2108624984 cites W2030184227 @default.
• W2108624984 cites W2032410204 @default.
• W2108624984 cites W2047453464 @default.
• W2108624984 cites W2052611780 @default.
• W2108624984 cites W2059241287 @default.
• W2108624984 cites W2061535202 @default.
• W2108624984 cites W2077906022 @default.
• W2108624984 cites W2078768877 @default.
• W2108624984 cites W2078841496 @default.
• W2108624984 cites W2079936148 @default.
• W2108624984 cites W2089307639 @default.
• W2108624984 cites W2099615865 @default.
• W2108624984 cites W2102825815 @default.
• W2108624984 cites W2106148947 @default.
• W2108624984 cites W2114979281 @default.
• W2108624984 cites W2122461248 @default.
• W2108624984 cites W2130025832 @default.
• W2108624984 cites W2141875239 @default.
• W2108624984 cites W2143886492 @default.
• W2108624984 cites W2143987043 @default.
• W2108624984 cites W2149486211 @default.
• W2108624984 cites W2154974507 @default.
• W2108624984 cites W2161403266 @default.
• W2108624984 cites W2166080650 @default.
• W2108624984 cites W2167226080 @default.
• W2108624984 cites W2168830217 @default.
• W2108624984 cites W2257366881 @default.
• W2108624984 doi "https://doi.org/10.1091/mbc.e12-07-0528" @default.
• W2108624984 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3639052" @default.
• W2108624984 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23468523" @default.
• W2108624984 hasPublicationYear "2013" @default.
• W2108624984 type Work @default.
• W2108624984 sameAs 2108624984 @default.
• W2108624984 citedByCount "43" @default.
• W2108624984 countsByYear W21086249842013 @default.
• W2108624984 countsByYear W21086249842014 @default.
• W2108624984 countsByYear W21086249842015 @default.
• W2108624984 countsByYear W21086249842016 @default.
• W2108624984 countsByYear W21086249842017 @default.
• W2108624984 countsByYear W21086249842018 @default.
• W2108624984 countsByYear W21086249842019 @default.
• W2108624984 countsByYear W21086249842020 @default.
• W2108624984 countsByYear W21086249842021 @default.
• W2108624984 countsByYear W21086249842022 @default.
• W2108624984 countsByYear W21086249842023 @default.
• W2108624984 crossrefType "journal-article" @default.
• W2108624984 hasAuthorship W2108624984A5045988991 @default.
• W2108624984 hasAuthorship W2108624984A5082585219 @default.
• W2108624984 hasBestOaLocation W21086249841 @default.
• W2108624984 hasConcept C104317684 @default.
• W2108624984 hasConcept C105702510 @default.
• W2108624984 hasConcept C143191323 @default.
• W2108624984 hasConcept C1491633281 @default.
• W2108624984 hasConcept C192838845 @default.
• W2108624984 hasConcept C30481170 @default.
• W2108624984 hasConcept C3453395 @default.
• W2108624984 hasConcept C47432576 @default.
• W2108624984 hasConcept C54355233 @default.
• W2108624984 hasConcept C70278784 @default.
• W2108624984 hasConcept C70547292 @default.
• W2108624984 hasConcept C85813293 @default.
• W2108624984 hasConcept C86803240 @default.
• W2108624984 hasConcept C93304396 @default.
• W2108624984 hasConcept C95444343 @default.
• W2108624984 hasConceptScore W2108624984C104317684 @default.
• W2108624984 hasConceptScore W2108624984C105702510 @default.
• W2108624984 hasConceptScore W2108624984C143191323 @default.
• W2108624984 hasConceptScore W2108624984C1491633281 @default.
• W2108624984 hasConceptScore W2108624984C192838845 @default.
• W2108624984 hasConceptScore W2108624984C30481170 @default.
• W2108624984 hasConceptScore W2108624984C3453395 @default.
• W2108624984 hasConceptScore W2108624984C47432576 @default.
• W2108624984 hasConceptScore W2108624984C54355233 @default.
• W2108624984 hasConceptScore W2108624984C70278784 @default.
• W2108624984 hasConceptScore W2108624984C70547292 @default.
• W2108624984 hasConceptScore W2108624984C85813293 @default.
• W2108624984 hasConceptScore W2108624984C86803240 @default.
• W2108624984 hasConceptScore W2108624984C93304396 @default.

• next