FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2108633170> ?p ?o ?g. }

• W2108633170 endingPage "3634" @default.
• W2108633170 startingPage "3629" @default.
• W2108633170 abstract "Lung cancer is the most frequent cancer worldwide, in terms of incidence and mortality. Due to challenges in the diagnosis of the disease, the 5‑year overall survival rate is only ~16%. Previous studies have suggested that malignant transformations originate from adult stem cells, and malignant lesions may therefore express stem‑cell‑associated markers. The purpose of the present study is to investigate the expression and clinical significance of the stem cell‑associated markers Sal‑like protein 4 (SALL4) and leucine‑rich repeat‑containing G‑protein coupled receptor 5 (LGR5) in lung cancer, and to provide novel diagnostic markers and targets for the treatment of lung cancer. The expression of the stem cell‑associated markers SALL4 and LGR5 was analyzed by immunohistochemistry performed on 135 human lung cancer tissue specimens and 10 non‑cancer lung tissue specimens. The clinical significance of the expression of these markers and correlation between their expression and clinical parameters was also assessed. SALL4 expression was highly upregulated in lung cancer tissues, but was not present in non‑cancerous lung tissues, and the sensitivity and specificity of SALL4 reached 88% and 100%, respectively. By contrast, LGR5 demonstrated 97% sensitivity, but the specificity was poor. Therefore, SALL4 may be an extremely useful diagnostic marker for lung cancer, but LGR5 is not as useful." @default.
• W2108633170 created "2016-06-24" @default.
• W2108633170 creator A5006940344 @default.
• W2108633170 creator A5016137434 @default.
• W2108633170 creator A5018920404 @default.
• W2108633170 creator A5020749911 @default.
• W2108633170 creator A5049075415 @default.
• W2108633170 creator A5054666711 @default.
• W2108633170 creator A5061630313 @default.
• W2108633170 creator A5069806912 @default.
• W2108633170 creator A5076067980 @default.
• W2108633170 creator A5082531587 @default.
• W2108633170 date "2015-09-30" @default.
• W2108633170 modified "2023-10-03" @default.
• W2108633170 title "Expression and clinical significance of SALL4 and LGR5 in patients with lung cancer" @default.
• W2108633170 cites W1970958778 @default.
• W2108633170 cites W1993333696 @default.
• W2108633170 cites W1994459176 @default.
• W2108633170 cites W1999356404 @default.
• W2108633170 cites W2002221745 @default.
• W2108633170 cites W2005241408 @default.
• W2108633170 cites W2012763636 @default.
• W2108633170 cites W2045956964 @default.
• W2108633170 cites W2046436753 @default.
• W2108633170 cites W2050149565 @default.
• W2108633170 cites W2053840813 @default.
• W2108633170 cites W2061750240 @default.
• W2108633170 cites W2088806119 @default.
• W2108633170 cites W2090562908 @default.
• W2108633170 cites W2096753123 @default.
• W2108633170 cites W2102085111 @default.
• W2108633170 cites W2103409987 @default.
• W2108633170 cites W2106787323 @default.
• W2108633170 cites W2120637479 @default.
• W2108633170 cites W2123891451 @default.
• W2108633170 cites W2125629897 @default.
• W2108633170 cites W2132705689 @default.
• W2108633170 cites W2136410889 @default.
• W2108633170 cites W2141325960 @default.
• W2108633170 cites W2141725935 @default.
• W2108633170 cites W2156381851 @default.
• W2108633170 cites W2164419770 @default.
• W2108633170 cites W2166818063 @default.
• W2108633170 doi "https://doi.org/10.3892/ol.2015.3772" @default.
• W2108633170 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4665631" @default.
• W2108633170 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26788181" @default.
• W2108633170 hasPublicationYear "2015" @default.
• W2108633170 type Work @default.
• W2108633170 sameAs 2108633170 @default.
• W2108633170 citedByCount "12" @default.
• W2108633170 countsByYear W21086331702016 @default.
• W2108633170 countsByYear W21086331702017 @default.
• W2108633170 countsByYear W21086331702018 @default.
• W2108633170 countsByYear W21086331702021 @default.
• W2108633170 countsByYear W21086331702022 @default.
• W2108633170 countsByYear W21086331702023 @default.
• W2108633170 crossrefType "journal-article" @default.
• W2108633170 hasAuthorship W2108633170A5006940344 @default.
• W2108633170 hasAuthorship W2108633170A5016137434 @default.
• W2108633170 hasAuthorship W2108633170A5018920404 @default.
• W2108633170 hasAuthorship W2108633170A5020749911 @default.
• W2108633170 hasAuthorship W2108633170A5049075415 @default.
• W2108633170 hasAuthorship W2108633170A5054666711 @default.
• W2108633170 hasAuthorship W2108633170A5061630313 @default.
• W2108633170 hasAuthorship W2108633170A5069806912 @default.
• W2108633170 hasAuthorship W2108633170A5076067980 @default.
• W2108633170 hasAuthorship W2108633170A5082531587 @default.
• W2108633170 hasBestOaLocation W21086331701 @default.
• W2108633170 hasConcept C10116572 @default.
• W2108633170 hasConcept C121608353 @default.
• W2108633170 hasConcept C126322002 @default.
• W2108633170 hasConcept C136302470 @default.
• W2108633170 hasConcept C142724271 @default.
• W2108633170 hasConcept C143998085 @default.
• W2108633170 hasConcept C204232928 @default.
• W2108633170 hasConcept C2776256026 @default.
• W2108633170 hasConcept C2781018059 @default.
• W2108633170 hasConcept C28328180 @default.
• W2108633170 hasConcept C29537977 @default.
• W2108633170 hasConcept C502942594 @default.
• W2108633170 hasConcept C54355233 @default.
• W2108633170 hasConcept C55427017 @default.
• W2108633170 hasConcept C63363279 @default.
• W2108633170 hasConcept C67082663 @default.
• W2108633170 hasConcept C71924100 @default.
• W2108633170 hasConcept C86803240 @default.
• W2108633170 hasConceptScore W2108633170C10116572 @default.
• W2108633170 hasConceptScore W2108633170C121608353 @default.
• W2108633170 hasConceptScore W2108633170C126322002 @default.
• W2108633170 hasConceptScore W2108633170C136302470 @default.
• W2108633170 hasConceptScore W2108633170C142724271 @default.
• W2108633170 hasConceptScore W2108633170C143998085 @default.
• W2108633170 hasConceptScore W2108633170C204232928 @default.
• W2108633170 hasConceptScore W2108633170C2776256026 @default.
• W2108633170 hasConceptScore W2108633170C2781018059 @default.
• W2108633170 hasConceptScore W2108633170C28328180 @default.
• W2108633170 hasConceptScore W2108633170C29537977 @default.
• W2108633170 hasConceptScore W2108633170C502942594 @default.

• next