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- W2108640588 abstract "To derive a prediction index based on the most salient history, laboratory and clinical parameters for identifying women at high risk of developing preeclampsia (PE) and to suggest a primary prevention.Non-pregnant women with a history of PE (n=101) were compared to non-pregnant parous women with a history of one or more successful normotensive pregnancies (n=50) but with comparable age, gestation and parity profiles. The parameters included history and clinical examination; laboratory studies (hemostasis, coagulation, vitamins); and morphological and functional tests (cardiovascular and renal functions). Stepwise logistic regression analysis was applied to develop a three step PE prediction index based on the most discriminant parameters. Strategies to prevent PE in the high-risk group are described.Identification of women at high risk of PE can be done efficiently (88% sensitivity and specificity) using a predictive index based on a simple history, laboratory, clinical and functional information. Strategies to prevent PE in our high-risk group have given encouraging results during next pregnancy.Our study gives a predictive index of PE outside of pregnancy and possibilities to do a primary prevention." @default.
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- W2108640588 date "2008-09-01" @default.
- W2108640588 modified "2023-10-16" @default.
- W2108640588 title "Détermination d’un index prédictif de la prééclampsie en préconceptionnel et propositions thérapeutiques de prévention primaire" @default.
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- W2108640588 doi "https://doi.org/10.1016/j.jgyn.2008.02.001" @default.
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