FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2108647566> ?p ?o ?g. }

• W2108647566 endingPage "394" @default.
• W2108647566 startingPage "386" @default.
• W2108647566 abstract "This study investigates the development of the Egyptian strain of Schistosoma haematobium and the resultant immunohistopathology and biochemical changes in organs affected. In addition, the response of different developmental stages of S. haematobium worms to praziquantel (PZQ) was examined. Schistosoma haematobium-infected hamsters were classified into 4 groups and were treated at day 35, 55, 75, and 95 postinfection (PI), respectively. Each group was subdivided into 3 subgroups. Two of them were treated orally with PZQ (300 mg/kg or 500 mg/kg divided equally on 2 consecutive days), and the third group was left without treatment. Treated groups were killed 20 days posttreatment. Infection with S. haematobium became patent 73 days PI; tissue egg load and worm fecundity were higher at 95 days and maximal 115 days PI, with an oogram pattern comparable to that in Schistosoma mansoni infection. In the liver, small cellular granulomas were observed 75 days PI, with preponderance of CD4+ T-cell phenotypes. In the urinary bladder, only submucosal focal Brunn's-nest formation and angiogenesis without typical granulomas were observed. Ninety-five and 115 days PI, confluent granulomata with multiple eggs in the center were observed in the liver and urinary bladder, with a preponderance of CD8+ positive T cells in the liver and hyperplasia of the urinary bladder epithelium with cystitis cystica and papillae formation. One hundred percent worm eradication was recorded with the higher dose of PZQ in animals treated 75 and 95 days PI. In conclusion, in spite of the long prepatent period of the Egyptian strain of S. haematobium, sensitivity to PZQ was recorded soon after infection. Granulomata were similar to those of S. mansoni in the livers and urinary bladders, but they were confluent with multiple eggs in the centers, hyperplasia of the urinary bladder urothelium with cystitis cystica, papillae, and Brunn's-nest formation predictive of malignant changes with no hepatocyte dysplasia." @default.
• W2108647566 created "2016-06-24" @default.
• W2108647566 creator A5019732277 @default.
• W2108647566 creator A5020669492 @default.
• W2108647566 creator A5060343244 @default.
• W2108647566 creator A5061631416 @default.
• W2108647566 creator A5080856520 @default.
• W2108647566 date "2008-04-01" @default.
• W2108647566 modified "2023-09-25" @default.
• W2108647566 title "Schistosoma haematobium (Egyptian Strain): Rate of Development and Effect of Praziquantel Treatment" @default.
• W2108647566 cites W1489577538 @default.
• W2108647566 cites W1515344661 @default.
• W2108647566 cites W1523518582 @default.
• W2108647566 cites W1536525955 @default.
• W2108647566 cites W1607033570 @default.
• W2108647566 cites W1764920507 @default.
• W2108647566 cites W1783115806 @default.
• W2108647566 cites W1965366343 @default.
• W2108647566 cites W1965932545 @default.
• W2108647566 cites W1966128018 @default.
• W2108647566 cites W1991386888 @default.
• W2108647566 cites W1996061749 @default.
• W2108647566 cites W2006561061 @default.
• W2108647566 cites W2021801795 @default.
• W2108647566 cites W2023159851 @default.
• W2108647566 cites W2029903395 @default.
• W2108647566 cites W2040545951 @default.
• W2108647566 cites W2042361710 @default.
• W2108647566 cites W2055312895 @default.
• W2108647566 cites W2069922231 @default.
• W2108647566 cites W2085246431 @default.
• W2108647566 cites W2089465395 @default.
• W2108647566 cites W2090746162 @default.
• W2108647566 cites W2091746068 @default.
• W2108647566 cites W2112823180 @default.
• W2108647566 cites W2123339897 @default.
• W2108647566 cites W2127286587 @default.
• W2108647566 cites W2134337203 @default.
• W2108647566 cites W2136152699 @default.
• W2108647566 cites W2166351790 @default.
• W2108647566 cites W2167207140 @default.
• W2108647566 cites W2169392450 @default.
• W2108647566 cites W2263023695 @default.
• W2108647566 cites W2264431933 @default.
• W2108647566 cites W2275218180 @default.
• W2108647566 cites W2397518918 @default.
• W2108647566 cites W2411355612 @default.
• W2108647566 cites W2417486311 @default.
• W2108647566 cites W2791764865 @default.
• W2108647566 cites W312292187 @default.
• W2108647566 cites W4245177871 @default.
• W2108647566 cites W67855806 @default.
• W2108647566 doi "https://doi.org/10.1645/ge-1270.1" @default.
• W2108647566 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18564739" @default.
• W2108647566 hasPublicationYear "2008" @default.
• W2108647566 type Work @default.
• W2108647566 sameAs 2108647566 @default.
• W2108647566 citedByCount "22" @default.
• W2108647566 countsByYear W21086475662012 @default.
• W2108647566 countsByYear W21086475662013 @default.
• W2108647566 countsByYear W21086475662014 @default.
• W2108647566 countsByYear W21086475662015 @default.
• W2108647566 countsByYear W21086475662016 @default.
• W2108647566 countsByYear W21086475662017 @default.
• W2108647566 countsByYear W21086475662018 @default.
• W2108647566 countsByYear W21086475662019 @default.
• W2108647566 countsByYear W21086475662020 @default.
• W2108647566 countsByYear W21086475662021 @default.
• W2108647566 countsByYear W21086475662022 @default.
• W2108647566 countsByYear W21086475662023 @default.
• W2108647566 crossrefType "journal-article" @default.
• W2108647566 hasAuthorship W2108647566A5019732277 @default.
• W2108647566 hasAuthorship W2108647566A5020669492 @default.
• W2108647566 hasAuthorship W2108647566A5060343244 @default.
• W2108647566 hasAuthorship W2108647566A5061631416 @default.
• W2108647566 hasAuthorship W2108647566A5080856520 @default.
• W2108647566 hasConcept C126322002 @default.
• W2108647566 hasConcept C134018914 @default.
• W2108647566 hasConcept C165901193 @default.
• W2108647566 hasConcept C16685009 @default.
• W2108647566 hasConcept C203014093 @default.
• W2108647566 hasConcept C2776225656 @default.
• W2108647566 hasConcept C2776863245 @default.
• W2108647566 hasConcept C2777445151 @default.
• W2108647566 hasConcept C2777562237 @default.
• W2108647566 hasConcept C2778491710 @default.
• W2108647566 hasConcept C2779726973 @default.
• W2108647566 hasConcept C2779744950 @default.
• W2108647566 hasConcept C2779762690 @default.
• W2108647566 hasConcept C71924100 @default.
• W2108647566 hasConcept C86803240 @default.
• W2108647566 hasConceptScore W2108647566C126322002 @default.
• W2108647566 hasConceptScore W2108647566C134018914 @default.
• W2108647566 hasConceptScore W2108647566C165901193 @default.
• W2108647566 hasConceptScore W2108647566C16685009 @default.
• W2108647566 hasConceptScore W2108647566C203014093 @default.
• W2108647566 hasConceptScore W2108647566C2776225656 @default.
• W2108647566 hasConceptScore W2108647566C2776863245 @default.

• next