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• W2108656962 abstract "The multicomponent reactions of aldehydes, electron deficient alkynes and amines have been successfully performed to yield a number of symmetrical 2,6-unsubstituted 1,4-dihydropyridines (1,4-DHPs). This method has been found generally applicable for the synthesis of both N-substituted and N-unsubstituted 1,4-DHPs by employing secondary amine to activate the alkyne component via enaminoester intermediates. The present method runs through an enamine type activation, which is different from the known approach employing AcOH as solvent." @default.
• W2108656962 created "2016-06-24" @default.
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• W2108656962 date "2014-03-01" @default.
• W2108656962 modified "2023-10-18" @default.
• W2108656962 title "Multicomponent Reactions for Diverse Synthesis of<i>N</i>-Substituted and NH 1,4-Dihydropyridines" @default.
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• W2108656962 doi "https://doi.org/10.1002/cjoc.201300918" @default.
• W2108656962 hasPublicationYear "2014" @default.
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