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- W2108673164 abstract "Twenty-six patients with proven craniopharyngioma were treated between 1954 and 1977. Total surgical removal was achieved in three patients (11.5%). Tumour recurrence was inevitable following incomplete surgical removal alone. Fifteen patients received post-operative radiotherapy following incomplete surgical removal of the tumour and eight patients (54%) survived, recurrence-free, for 5 years or more. Post- operative radiotherapy, delivering a central target absorbed dose of 4500 cGy in 20 fractions over 28 days (1520 rets) or more, significantly improved the recurrence-free survival (P = 0.019) with minimal morbidity. Partial resection of recurrent tumour carried a high mortality rate. Minimal salvage surgery in the form of cyst aspiration sometimes resulted in worthwhile palliation. Twenty-six patients with proven craniopharyngioma were treated between 1954 and 1977. Total surgical removal was achieved in three patients (11.5%). Tumour recurrence was inevitable following incomplete surgical removal alone. Fifteen patients received post-operative radiotherapy following incomplete surgical removal of the tumour and eight patients (54%) survived, recurrence-free, for 5 years or more. Post- operative radiotherapy, delivering a central target absorbed dose of 4500 cGy in 20 fractions over 28 days (1520 rets) or more, significantly improved the recurrence-free survival (P = 0.019) with minimal morbidity. Partial resection of recurrent tumour carried a high mortality rate. Minimal salvage surgery in the form of cyst aspiration sometimes resulted in worthwhile palliation." @default.
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- W2108673164 date "1983-01-01" @default.
- W2108673164 modified "2023-10-12" @default.
- W2108673164 title "The management of craniopharyngioma" @default.
- W2108673164 cites W1980150138 @default.
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- W2108673164 doi "https://doi.org/10.1016/s0009-9260(83)80409-7" @default.
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