FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2108683648> ?p ?o ?g. }

• W2108683648 endingPage "137" @default.
• W2108683648 startingPage "131" @default.
• W2108683648 abstract "RA associates with an increased rate of sudden cardiac death (SCD). A prolonged QTc interval has been associated with arrhythmogenic and SCD in patients with long QT syndrome. Despite the previously reported contemporary association of CRP with SCD, thus far no studies have examined the association of QTc with mortality in RA, a condition characterized by high inflammatory burden. The aim of this study was to examine the role of electrocardiography (QT corrected interval) in predicting all-cause mortality in patients with RA who have an increased rate of SCD and a high inflammatory burden.Three hundred and fifty-seven RA patients with detailed baseline clinical characterization and 12-lead ECGs were followed up for a mean of 73.0 (S.D. 18.3) months. Linear and Cox regression analyses were used to identify variables that associate with QTc and examine its association with all-cause mortality.The patients' mean age was 60.6 (S.D. 12.0) years, 267 (74.8%) were females and 54 (15.1%) died during the follow-up period. Age (β = 0.231, P < 0.001), gender (β = 0.137, P = 0.008) and CRP (β = 0.144, P = 0.006) associated independently with QTc in RA patients. The crude hazard ratio (HR) for total mortality per 50-ms increase in QTc was 2.17 (95% CI 1.21, 3.90). This association remained significant [HR = 2.18 (95% CI 1.09, 4.35)] after adjustment for identified confounders (cardiovascular and RA specific), but was lost [HR = 1.73 (95% CI 0.83, 3.62)] when CRP was included in the model.A 50-ms increase in QTc interval associates with a doubling of the hazard for all-cause mortality in patients with RA. The observed contemporary association of QTc with CRP levels indicates a potentially hazardous interplay between inflammation and arrhythmogenesis. Future studies are needed to confirm the above findings and explore underlying mechanisms." @default.
• W2108683648 created "2016-06-24" @default.
• W2108683648 creator A5010486338 @default.
• W2108683648 creator A5012341759 @default.
• W2108683648 creator A5024134135 @default.
• W2108683648 creator A5034028991 @default.
• W2108683648 creator A5036673090 @default.
• W2108683648 creator A5047358407 @default.
• W2108683648 creator A5052899816 @default.
• W2108683648 date "2013-10-03" @default.
• W2108683648 modified "2023-10-14" @default.
• W2108683648 title "Prolonged QTc interval predicts all-cause mortality in patients with rheumatoid arthritis: an association driven by high inflammatory burden" @default.
• W2108683648 cites W1678145773 @default.
• W2108683648 cites W1965151982 @default.
• W2108683648 cites W1985988199 @default.
• W2108683648 cites W1988368217 @default.
• W2108683648 cites W1993160453 @default.
• W2108683648 cites W2003692571 @default.
• W2108683648 cites W2012684316 @default.
• W2108683648 cites W2024431098 @default.
• W2108683648 cites W2035292279 @default.
• W2108683648 cites W2057763645 @default.
• W2108683648 cites W2058217066 @default.
• W2108683648 cites W2076524041 @default.
• W2108683648 cites W2096814087 @default.
• W2108683648 cites W2103777208 @default.
• W2108683648 cites W2107023223 @default.
• W2108683648 cites W2131308754 @default.
• W2108683648 cites W2135547862 @default.
• W2108683648 cites W2137393768 @default.
• W2108683648 cites W2152348310 @default.
• W2108683648 cites W2155159583 @default.
• W2108683648 cites W2161465441 @default.
• W2108683648 cites W3217261033 @default.
• W2108683648 doi "https://doi.org/10.1093/rheumatology/ket338" @default.
• W2108683648 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24097136" @default.
• W2108683648 hasPublicationYear "2013" @default.
• W2108683648 type Work @default.
• W2108683648 sameAs 2108683648 @default.
• W2108683648 citedByCount "68" @default.
• W2108683648 countsByYear W21086836482014 @default.
• W2108683648 countsByYear W21086836482015 @default.
• W2108683648 countsByYear W21086836482016 @default.
• W2108683648 countsByYear W21086836482017 @default.
• W2108683648 countsByYear W21086836482018 @default.
• W2108683648 countsByYear W21086836482019 @default.
• W2108683648 countsByYear W21086836482020 @default.
• W2108683648 countsByYear W21086836482021 @default.
• W2108683648 countsByYear W21086836482022 @default.
• W2108683648 countsByYear W21086836482023 @default.
• W2108683648 crossrefType "journal-article" @default.
• W2108683648 hasAuthorship W2108683648A5010486338 @default.
• W2108683648 hasAuthorship W2108683648A5012341759 @default.
• W2108683648 hasAuthorship W2108683648A5024134135 @default.
• W2108683648 hasAuthorship W2108683648A5034028991 @default.
• W2108683648 hasAuthorship W2108683648A5036673090 @default.
• W2108683648 hasAuthorship W2108683648A5047358407 @default.
• W2108683648 hasAuthorship W2108683648A5052899816 @default.
• W2108683648 hasBestOaLocation W21086836481 @default.
• W2108683648 hasConcept C118441451 @default.
• W2108683648 hasConcept C126322002 @default.
• W2108683648 hasConcept C164705383 @default.
• W2108683648 hasConcept C207103383 @default.
• W2108683648 hasConcept C2775935837 @default.
• W2108683648 hasConcept C2777575956 @default.
• W2108683648 hasConcept C2780040984 @default.
• W2108683648 hasConcept C44249647 @default.
• W2108683648 hasConcept C50382708 @default.
• W2108683648 hasConcept C71924100 @default.
• W2108683648 hasConcept C77350462 @default.
• W2108683648 hasConceptScore W2108683648C118441451 @default.
• W2108683648 hasConceptScore W2108683648C126322002 @default.
• W2108683648 hasConceptScore W2108683648C164705383 @default.
• W2108683648 hasConceptScore W2108683648C207103383 @default.
• W2108683648 hasConceptScore W2108683648C2775935837 @default.
• W2108683648 hasConceptScore W2108683648C2777575956 @default.
• W2108683648 hasConceptScore W2108683648C2780040984 @default.
• W2108683648 hasConceptScore W2108683648C44249647 @default.
• W2108683648 hasConceptScore W2108683648C50382708 @default.
• W2108683648 hasConceptScore W2108683648C71924100 @default.
• W2108683648 hasConceptScore W2108683648C77350462 @default.
• W2108683648 hasIssue "1" @default.
• W2108683648 hasLocation W21086836481 @default.
• W2108683648 hasLocation W21086836482 @default.
• W2108683648 hasOpenAccess W2108683648 @default.
• W2108683648 hasPrimaryLocation W21086836481 @default.
• W2108683648 hasRelatedWork W1727188710 @default.
• W2108683648 hasRelatedWork W2079433673 @default.
• W2108683648 hasRelatedWork W2119154902 @default.
• W2108683648 hasRelatedWork W2133235702 @default.
• W2108683648 hasRelatedWork W2203903734 @default.
• W2108683648 hasRelatedWork W2371249220 @default.
• W2108683648 hasRelatedWork W2762750678 @default.
• W2108683648 hasRelatedWork W2917746345 @default.
• W2108683648 hasRelatedWork W4376871959 @default.
• W2108683648 hasRelatedWork W82075950 @default.
• W2108683648 hasVolume "53" @default.
• W2108683648 isParatext "false" @default.

• next