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- W2108686492 abstract "<h2>Abstract</h2> THE volumes of red cells and plasma were directly estimated by means of the chromium-labelling technique and Evans-blue dyedilution method respectively, in 78 anæmic and 20 healthy pregnant Nigerian women. In severe anæmia in pregnancy, the P.C.V. and hæmoglobin concentration of the peripheral venous blood give a very good indication of the total red-cell mass before the anæmia is treated; plasma-volume is significantly increased and compensates for the red-cell deficiency. In the presence of multiple pregnancies, gross splenomegaly, and anæmic cardiac failure, larger plasma-volume expansion is found. Total blood-volume is reduced in 25% of the patients in whom the hæmoglobin concentration is less than 4·4 g. per 100 ml., the P.C.V. of the peripheral venous blood is less than 14%, and the total red-cell mass is less than 10 ml. per kg. body-weight. The hæmatocrit ratio is not constant in severe anaemia in pregnancy when the P.C.V. is less than 25%. The total blood-volume can therefore be reliably estimated only by simultaneous measurements of red-cell and plasma-volumes." @default.
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- W2108686492 date "1967-01-01" @default.
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- W2108686492 title "BLOOD-VOLUME CHANGES IN SEVERE ANÆMIA IN PREGNANCY" @default.
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- W2108686492 doi "https://doi.org/10.1016/s0140-6736(67)92424-5" @default.
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