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- W2108697752 abstract "Bound and clamped: A novel heterocyclic base modification, the guanidino G-clamp, is designed to allow two Hoogsteen-type hydrogen bonds to form between the amino and imino nitrogen atoms of a tethered guanidinium group to O6 and N7 of guanosine, which results in a total of five hydrogen bonds (broken lines, see picture). Details of a crystal structure at 1.0-Å resolution of a modified DNA decamer containing this guanidino G-clamp analogue demonstrate its mechanism of binding. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2002/z17542_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article." @default.
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- W2108697752 date "2002-01-02" @default.
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- W2108697752 title "Direct Observation of a Cytosine Analogue that Forms Five Hydrogen Bonds to Guanosine: Guanidino G-Clamp" @default.
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- W2108697752 doi "https://doi.org/10.1002/1521-3773(20020104)41:1<115::aid-anie115>3.0.co;2-r" @default.
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