Matches in SemOpenAlex for { <https://semopenalex.org/work/W2108706378> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2108706378 endingPage "31" @default.
- W2108706378 startingPage "428" @default.
- W2108706378 abstract "To determine the effectiveness of sentinel lymph-node (SLN) biopsy for melanoma of the trunk and extremities.Case series review.Royal Victoria Hospital, a Canadian university hospital.Thirty-six patients (18 women and 18 men) seen between October 1996 and December 1998 with melanoma 1 mm or more in thickness with clinically negative lymph-node basins. Follow-up was 396 days.SLN biopsy. Technetium-99m filtered sulfur colloid (0.5 mCi) was injected intradermally around the melanoma or the excision scar 10 to 15 minutes before the surgical skin preparation. The identification of the SLN(s) was done with a hand-held gamma probe. Local anesthesia was used mostly for inguinal SLN biopsy whereas general anesthesia was usually required for axillary SLN biopsy. Preoperative lymphoscintigraphy was used only for trunk melanomas.Morbidity, successful identification of the sentinel node and locoregional recurrence.The mean age of patients at diagnosis was 53.4 years (range from 22-76 yr). The melanomas were distributed between the lower extremities (20 patients), upper extremities (8 patients) and trunk (8 patients). The mean Breslow thickness was 2.35 mm (range from 1-8 mm). Lymphoscintigraphy accurately localized the lymph-node drainage basin for trunk melanomas. In 1 patient the SLN could not be identified because the radiocolloid failed to migrate (failure rate 2.8%). The average number of SLNs removed was 1.97. Eight patients (22%) had sentinel nodes positive for malignant disease. The postoperative complication rate was 8.5%. Seven of 8 patients with positive SLNs underwent a complete node dissection (1 patient refused). Of the completion dissections only 2 patients had positive non-SLNs. All patients with positive nodes received interferon alpha-2b as adjuvant treatment. At follow-up, 34 patients are alive with no evidence of disease, 1 patient with a positive SLN is alive with distant metastatic disease and 1 patient with a negative SLN is dead of disseminated disease.SLN biopsy is a feasible technique with an acceptable failure rate and is thus a useful tool in the surgical management of melanoma." @default.
- W2108706378 created "2016-06-24" @default.
- W2108706378 creator A5022692949 @default.
- W2108706378 creator A5047702677 @default.
- W2108706378 creator A5050583900 @default.
- W2108706378 creator A5053354564 @default.
- W2108706378 date "2001-12-01" @default.
- W2108706378 modified "2023-09-23" @default.
- W2108706378 title "Sentinel lymph-node biopsy for melanoma of the trunk and extremities: the McGill experience." @default.
- W2108706378 cites W1569358500 @default.
- W2108706378 cites W1828940258 @default.
- W2108706378 cites W1832922477 @default.
- W2108706378 cites W1982131839 @default.
- W2108706378 cites W2007807118 @default.
- W2108706378 cites W2052280998 @default.
- W2108706378 cites W2060109939 @default.
- W2108706378 cites W2062996015 @default.
- W2108706378 cites W2088037555 @default.
- W2108706378 cites W2134279984 @default.
- W2108706378 cites W2141685284 @default.
- W2108706378 cites W2143422545 @default.
- W2108706378 cites W2168821180 @default.
- W2108706378 cites W2172107283 @default.
- W2108706378 cites W2396748864 @default.
- W2108706378 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3692676" @default.
- W2108706378 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11764875" @default.
- W2108706378 hasPublicationYear "2001" @default.
- W2108706378 type Work @default.
- W2108706378 sameAs 2108706378 @default.
- W2108706378 citedByCount "5" @default.
- W2108706378 countsByYear W21087063782014 @default.
- W2108706378 countsByYear W21087063782018 @default.
- W2108706378 crossrefType "journal-article" @default.
- W2108706378 hasAuthorship W2108706378A5022692949 @default.
- W2108706378 hasAuthorship W2108706378A5047702677 @default.
- W2108706378 hasAuthorship W2108706378A5050583900 @default.
- W2108706378 hasAuthorship W2108706378A5053354564 @default.
- W2108706378 hasConcept C121608353 @default.
- W2108706378 hasConcept C126322002 @default.
- W2108706378 hasConcept C126838900 @default.
- W2108706378 hasConcept C141071460 @default.
- W2108706378 hasConcept C142724271 @default.
- W2108706378 hasConcept C179671157 @default.
- W2108706378 hasConcept C18903297 @default.
- W2108706378 hasConcept C2775862295 @default.
- W2108706378 hasConcept C2775934546 @default.
- W2108706378 hasConcept C2777658100 @default.
- W2108706378 hasConcept C2777793825 @default.
- W2108706378 hasConcept C2780212769 @default.
- W2108706378 hasConcept C2780849966 @default.
- W2108706378 hasConcept C2781197403 @default.
- W2108706378 hasConcept C502942594 @default.
- W2108706378 hasConcept C530470458 @default.
- W2108706378 hasConcept C71924100 @default.
- W2108706378 hasConcept C86803240 @default.
- W2108706378 hasConceptScore W2108706378C121608353 @default.
- W2108706378 hasConceptScore W2108706378C126322002 @default.
- W2108706378 hasConceptScore W2108706378C126838900 @default.
- W2108706378 hasConceptScore W2108706378C141071460 @default.
- W2108706378 hasConceptScore W2108706378C142724271 @default.
- W2108706378 hasConceptScore W2108706378C179671157 @default.
- W2108706378 hasConceptScore W2108706378C18903297 @default.
- W2108706378 hasConceptScore W2108706378C2775862295 @default.
- W2108706378 hasConceptScore W2108706378C2775934546 @default.
- W2108706378 hasConceptScore W2108706378C2777658100 @default.
- W2108706378 hasConceptScore W2108706378C2777793825 @default.
- W2108706378 hasConceptScore W2108706378C2780212769 @default.
- W2108706378 hasConceptScore W2108706378C2780849966 @default.
- W2108706378 hasConceptScore W2108706378C2781197403 @default.
- W2108706378 hasConceptScore W2108706378C502942594 @default.
- W2108706378 hasConceptScore W2108706378C530470458 @default.
- W2108706378 hasConceptScore W2108706378C71924100 @default.
- W2108706378 hasConceptScore W2108706378C86803240 @default.
- W2108706378 hasIssue "6" @default.
- W2108706378 hasLocation W21087063781 @default.
- W2108706378 hasOpenAccess W2108706378 @default.
- W2108706378 hasPrimaryLocation W21087063781 @default.
- W2108706378 hasRelatedWork W1964722288 @default.
- W2108706378 hasRelatedWork W1964836677 @default.
- W2108706378 hasRelatedWork W2065187766 @default.
- W2108706378 hasRelatedWork W2108472133 @default.
- W2108706378 hasRelatedWork W2108706378 @default.
- W2108706378 hasRelatedWork W2149134122 @default.
- W2108706378 hasRelatedWork W2434954638 @default.
- W2108706378 hasRelatedWork W3112395742 @default.
- W2108706378 hasRelatedWork W4220843058 @default.
- W2108706378 hasRelatedWork W2038124116 @default.
- W2108706378 hasVolume "44" @default.
- W2108706378 isParatext "false" @default.
- W2108706378 isRetracted "false" @default.
- W2108706378 magId "2108706378" @default.
- W2108706378 workType "article" @default.