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- W2108750141 abstract "To the Editor:With regard to interventional treatment of acute ischemic stroke, neurologists and neurointerventionalists do not speak the same language. In studies, neurologists are interested in patient outcome whereas neurointerventionalists often focus on the success of recanalization. The systematic review by O'Rourke et al1 of randomized trials, comparing percutaneous vascular interventions plus medical treatment with medical treatment on its own for acute stroke, drew concrete conclusions. Compared with standard medical treatment, intervention administered up to 6 hours after a stroke significantly increased the proportion of patients with favorable outcome. Intervention also significantly increased the risk of intracranial hemorrhage, but not that of mortality.1These are precise results, but they do not apply to current clinical practice. In these clinical trials, standard medical therapy was not intravenous (IV) thrombolysis, which has since become established as standard therapy in acute ischemic stroke. The ECASS 3 study showed clearly that IV alteplase given up to 4.5 hours after onset of stroke symptoms is …" @default.
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- W2108750141 date "2011-09-01" @default.
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- W2108750141 title "Letter by Papanagiotou et al Regarding Article, “Percutaneous Vascular Interventions for Acute Ischemic Stroke”" @default.
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- W2108750141 doi "https://doi.org/10.1161/strokeaha.111.620989" @default.
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