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- W2108771296 abstract "SUMMARY: Free and membrane-bound ribosomes were isolated from wild-type Neurospora crassa containing the genetic backgrund Em 5297a at 6, 12, 18, 24, 36, 48 and 72 h of growth. Log phase began at 8 h and continued to the end of 24 h, the beginning of the stationary phase. The ratio of free to membrane-bound ribosomes remained relatively constant during log phase. During stationary phase, the ratio of free to bound ribosomes rose sharply because of a decrease in the concentration of bound ribosomes. Free ribosomes are generally assumed to synthesize intracellular proteins, whereas bound ribosomes synthesize proteins intended for secretion. These changes in membrane-bound ribosomes can be correlated with the specific activity of wallbound invertase (an intracellular enzyme) of the same strain of Neurospora. We suggest that this decrease in membrane-bound ribosomes during stationary phase is of physiological significance and occurs because of a decreasing synthesis of secreted proteins." @default.
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- W2108771296 date "1973-12-01" @default.
- W2108771296 modified "2023-09-27" @default.
- W2108771296 title "Changes in Free and Membrane-bound Ribosomes during the Vegetative Growth of Neurospora crassa" @default.
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- W2108771296 doi "https://doi.org/10.1099/00221287-79-2-181" @default.
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