Matches in SemOpenAlex for { <https://semopenalex.org/work/W2108798814> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2108798814 endingPage "1005" @default.
- W2108798814 startingPage "1001" @default.
- W2108798814 abstract "<h3>Background</h3> A marked response to dopamine replacement therapy is important in supporting a diagnosis of idiopathic Parkinson9s disease (PD). The aim of the study was to compare PD patients9 subjective rating of improvement with measured improvement on a number of scales. <h3>Methods</h3> People with clinically defined PD were identified from a prospective long term follow-up study of incident parkinsonian patients. Changes in the Unified Parkinson9s Disease Rating Scale (UPDRS) (activities of daily living and motor subsections), timed tests and Parkinson9s Disease Questionnaire, full version, between assessments immediately before starting adequate dopamine replacement and the two subsequent follow-up assessments (mean 6 and 12 months after baseline) were calculated. These were compared with the patients9 own subjective ratings of improvement (nil, slight, moderate, good, excellent). <h3>Results</h3> 133 patients were included (mean age 71 years, 56% men). Thirty-eight patients were treated with a dopamine agonist and 95 with l-dopa (median l-dopa equivalent dose 300 mg). Most patients showed improvements in their measured scores but there was no statistically significant association between these scores and the patient subjective response, except for the motor UPDRS at the first follow-up. A third of those who showed no improvement in their motor UPDRS at the first follow-up rated their improvement as moderate or better, while 29% of those whose motor UPDRS improved by over 50% said they had no or slight improvement. <h3>Conclusion</h3> PD patients9 subjective ratings of their degree of improvement often do not accurately reflect the degree of objective change in parkinsonian impairment or disability. Clinicians should record a simple measure of motor impairment before and after treatment to assess treatment response more accurately." @default.
- W2108798814 created "2016-06-24" @default.
- W2108798814 creator A5029739175 @default.
- W2108798814 creator A5073259686 @default.
- W2108798814 creator A5083154337 @default.
- W2108798814 date "2012-05-24" @default.
- W2108798814 modified "2023-10-15" @default.
- W2108798814 title "Comparison of patient rated treatment response with measured improvement in Parkinson's disease" @default.
- W2108798814 cites W1544359545 @default.
- W2108798814 cites W1562359367 @default.
- W2108798814 cites W1847168837 @default.
- W2108798814 cites W1969765051 @default.
- W2108798814 cites W1970534639 @default.
- W2108798814 cites W1977314903 @default.
- W2108798814 cites W2005541583 @default.
- W2108798814 cites W2008827081 @default.
- W2108798814 cites W2077151956 @default.
- W2108798814 cites W2089085990 @default.
- W2108798814 cites W2090966817 @default.
- W2108798814 cites W2132881915 @default.
- W2108798814 cites W2147111512 @default.
- W2108798814 cites W2165104199 @default.
- W2108798814 cites W2166447559 @default.
- W2108798814 cites W2409175306 @default.
- W2108798814 cites W2972597017 @default.
- W2108798814 cites W39805860 @default.
- W2108798814 doi "https://doi.org/10.1136/jnnp-2012-302741" @default.
- W2108798814 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22626942" @default.
- W2108798814 hasPublicationYear "2012" @default.
- W2108798814 type Work @default.
- W2108798814 sameAs 2108798814 @default.
- W2108798814 citedByCount "22" @default.
- W2108798814 countsByYear W21087988142013 @default.
- W2108798814 countsByYear W21087988142014 @default.
- W2108798814 countsByYear W21087988142015 @default.
- W2108798814 countsByYear W21087988142016 @default.
- W2108798814 countsByYear W21087988142017 @default.
- W2108798814 countsByYear W21087988142018 @default.
- W2108798814 countsByYear W21087988142019 @default.
- W2108798814 countsByYear W21087988142021 @default.
- W2108798814 countsByYear W21087988142022 @default.
- W2108798814 countsByYear W21087988142023 @default.
- W2108798814 crossrefType "journal-article" @default.
- W2108798814 hasAuthorship W2108798814A5029739175 @default.
- W2108798814 hasAuthorship W2108798814A5073259686 @default.
- W2108798814 hasAuthorship W2108798814A5083154337 @default.
- W2108798814 hasBestOaLocation W21087988141 @default.
- W2108798814 hasConcept C126322002 @default.
- W2108798814 hasConcept C138496976 @default.
- W2108798814 hasConcept C15744967 @default.
- W2108798814 hasConcept C1862650 @default.
- W2108798814 hasConcept C187212893 @default.
- W2108798814 hasConcept C2779134260 @default.
- W2108798814 hasConcept C2779734285 @default.
- W2108798814 hasConcept C3018987647 @default.
- W2108798814 hasConcept C71924100 @default.
- W2108798814 hasConcept C83849319 @default.
- W2108798814 hasConcept C99508421 @default.
- W2108798814 hasConceptScore W2108798814C126322002 @default.
- W2108798814 hasConceptScore W2108798814C138496976 @default.
- W2108798814 hasConceptScore W2108798814C15744967 @default.
- W2108798814 hasConceptScore W2108798814C1862650 @default.
- W2108798814 hasConceptScore W2108798814C187212893 @default.
- W2108798814 hasConceptScore W2108798814C2779134260 @default.
- W2108798814 hasConceptScore W2108798814C2779734285 @default.
- W2108798814 hasConceptScore W2108798814C3018987647 @default.
- W2108798814 hasConceptScore W2108798814C71924100 @default.
- W2108798814 hasConceptScore W2108798814C83849319 @default.
- W2108798814 hasConceptScore W2108798814C99508421 @default.
- W2108798814 hasIssue "10" @default.
- W2108798814 hasLocation W21087988141 @default.
- W2108798814 hasLocation W21087988142 @default.
- W2108798814 hasOpenAccess W2108798814 @default.
- W2108798814 hasPrimaryLocation W21087988141 @default.
- W2108798814 hasRelatedWork W1605377341 @default.
- W2108798814 hasRelatedWork W2066174631 @default.
- W2108798814 hasRelatedWork W2113805846 @default.
- W2108798814 hasRelatedWork W2323168023 @default.
- W2108798814 hasRelatedWork W2509676662 @default.
- W2108798814 hasRelatedWork W2775767512 @default.
- W2108798814 hasRelatedWork W3088070796 @default.
- W2108798814 hasRelatedWork W3117140735 @default.
- W2108798814 hasRelatedWork W3118175407 @default.
- W2108798814 hasRelatedWork W3150365316 @default.
- W2108798814 hasVolume "83" @default.
- W2108798814 isParatext "false" @default.
- W2108798814 isRetracted "false" @default.
- W2108798814 magId "2108798814" @default.
- W2108798814 workType "article" @default.