Matches in SemOpenAlex for { <https://semopenalex.org/work/W2108858181> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W2108858181 endingPage "207" @default.
- W2108858181 startingPage "201" @default.
- W2108858181 abstract "Background: Current guidelines/algorithms recommend atypical antipsychotics as first-line agents for the treatment of schizophrenia. Because there are extensive healthcare costs associated with the treatment of schizophrenia, many institutions and health systems are faced with making restrictive formulary decisions regarding the use of atypical antipsychotics. Often, medication acquisition costs are the driving force behind formulary decisions, while other treatment factors are not considered. Objective: To apply a multi-attribute utility theory (MAUT) analysis to aid in the selection of a preferred agent among the atypical antipsychotics for the treatment of schizophrenia. Methods: Five atypical antipsychotics (risperidone, olanzapine, quetiapine, ziprasidone, aripiprazole) were selected as the alternative agents to be included in the MAUT analysis. The attributes identified for inclusion in the analysis were efficacy, adverse effects, cost, and adherence, with relative weights of 35%, 35%, 20%, and 10%, respectively. For each agent, attribute scores were calculated, weighted, and then summed to generate a total utility score. The agent with the highest total utility score was considered the preferred agent. Results: Aripiprazole, with a total utility score of 75.8, was the alternative agent with the highest total utility score in this model. This was followed by ziprasidone, risperidone, and quetiapine, with total utility scores of 71.8, 69.0, and 65.9, respectively. Olanzapine received the lowest total utility score. A sensitivity analysis was performed and failed to displace aripiprazole as the agent with the highest total utility score. Conclusions: This model suggests that aripiprazole should be considered a preferred agent for the treatment of schizophrenia unless found to be otherwise inappropriate." @default.
- W2108858181 created "2016-06-24" @default.
- W2108858181 creator A5018156549 @default.
- W2108858181 creator A5026604545 @default.
- W2108858181 creator A5052890800 @default.
- W2108858181 creator A5085256875 @default.
- W2108858181 date "2007-02-01" @default.
- W2108858181 modified "2023-10-16" @default.
- W2108858181 title "Schizophrenia: Multi-Attribute Utility Theory Approach to Selection of Atypical Antipsychotics" @default.
- W2108858181 cites W1967747218 @default.
- W2108858181 cites W1968943209 @default.
- W2108858181 cites W2043671457 @default.
- W2108858181 cites W2069024810 @default.
- W2108858181 cites W2097648013 @default.
- W2108858181 cites W2111883919 @default.
- W2108858181 cites W2117106955 @default.
- W2108858181 cites W2139560403 @default.
- W2108858181 cites W2143962486 @default.
- W2108858181 cites W2147033083 @default.
- W2108858181 cites W2156065126 @default.
- W2108858181 cites W2159155203 @default.
- W2108858181 cites W2168800481 @default.
- W2108858181 cites W2916678927 @default.
- W2108858181 cites W4232541108 @default.
- W2108858181 cites W2169611417 @default.
- W2108858181 doi "https://doi.org/10.1345/aph.1g607" @default.
- W2108858181 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17311836" @default.
- W2108858181 hasPublicationYear "2007" @default.
- W2108858181 type Work @default.
- W2108858181 sameAs 2108858181 @default.
- W2108858181 citedByCount "14" @default.
- W2108858181 countsByYear W21088581812014 @default.
- W2108858181 countsByYear W21088581812015 @default.
- W2108858181 countsByYear W21088581812017 @default.
- W2108858181 countsByYear W21088581812019 @default.
- W2108858181 crossrefType "journal-article" @default.
- W2108858181 hasAuthorship W2108858181A5018156549 @default.
- W2108858181 hasAuthorship W2108858181A5026604545 @default.
- W2108858181 hasAuthorship W2108858181A5052890800 @default.
- W2108858181 hasAuthorship W2108858181A5085256875 @default.
- W2108858181 hasConcept C100406419 @default.
- W2108858181 hasConcept C118552586 @default.
- W2108858181 hasConcept C2776412080 @default.
- W2108858181 hasConcept C2776619155 @default.
- W2108858181 hasConcept C2776921671 @default.
- W2108858181 hasConcept C2777270317 @default.
- W2108858181 hasConcept C2780057945 @default.
- W2108858181 hasConcept C2780211496 @default.
- W2108858181 hasConcept C2780494398 @default.
- W2108858181 hasConcept C2780634440 @default.
- W2108858181 hasConcept C71924100 @default.
- W2108858181 hasConcept C98274493 @default.
- W2108858181 hasConceptScore W2108858181C100406419 @default.
- W2108858181 hasConceptScore W2108858181C118552586 @default.
- W2108858181 hasConceptScore W2108858181C2776412080 @default.
- W2108858181 hasConceptScore W2108858181C2776619155 @default.
- W2108858181 hasConceptScore W2108858181C2776921671 @default.
- W2108858181 hasConceptScore W2108858181C2777270317 @default.
- W2108858181 hasConceptScore W2108858181C2780057945 @default.
- W2108858181 hasConceptScore W2108858181C2780211496 @default.
- W2108858181 hasConceptScore W2108858181C2780494398 @default.
- W2108858181 hasConceptScore W2108858181C2780634440 @default.
- W2108858181 hasConceptScore W2108858181C71924100 @default.
- W2108858181 hasConceptScore W2108858181C98274493 @default.
- W2108858181 hasIssue "2" @default.
- W2108858181 hasLocation W21088581811 @default.
- W2108858181 hasLocation W21088581812 @default.
- W2108858181 hasOpenAccess W2108858181 @default.
- W2108858181 hasPrimaryLocation W21088581811 @default.
- W2108858181 hasRelatedWork W125839487 @default.
- W2108858181 hasRelatedWork W1509131650 @default.
- W2108858181 hasRelatedWork W1966343709 @default.
- W2108858181 hasRelatedWork W2015110280 @default.
- W2108858181 hasRelatedWork W2036715112 @default.
- W2108858181 hasRelatedWork W2050310642 @default.
- W2108858181 hasRelatedWork W2076855008 @default.
- W2108858181 hasRelatedWork W2108858181 @default.
- W2108858181 hasRelatedWork W2111838078 @default.
- W2108858181 hasRelatedWork W2349185474 @default.
- W2108858181 hasVolume "41" @default.
- W2108858181 isParatext "false" @default.
- W2108858181 isRetracted "false" @default.
- W2108858181 magId "2108858181" @default.
- W2108858181 workType "article" @default.