FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2108974407> ?p ?o ?g. }

• W2108974407 endingPage "713" @default.
• W2108974407 startingPage "709" @default.
• W2108974407 abstract "Background The combination of atovaquone and proguanil is highly effective and safe for the treatment of Plasmodium falciparum malaria. We aimed in this randomised, double-blind, placebo-controlled study to assess the efficacy and safety of this combination for malaria prophylaxis. Methods 320 children who lived in a hyperendemic area for P falciparum malaria were stratified by weight and randomly assigned atovaquone plus proguanil or placebo once daily for 12 weeks. All children received initial curative treatment with atovaquone and proguanil before the start of chemosuppression. We recorded adverse events daily and collected thick blood smears once a week. The primary endpoint was a positive blood smear. Findings 25 of 140 children in the placebo group and none of the 125 children in the atovaquone plus proguanil group had positive smears during chemosuppression (p<0·001). Adverse events during the chemosuppression phase did not differ between the groups. Interpretation The combination of atovaquone plus proguanil is a highly effective and well-tolerated chemosuppressive antimalarial in children. This drug combination could replace current regimens." @default.
• W2108974407 created "2016-06-24" @default.
• W2108974407 creator A5025601117 @default.
• W2108974407 creator A5043369631 @default.
• W2108974407 creator A5044133610 @default.
• W2108974407 creator A5087769443 @default.
• W2108974407 creator A5090444000 @default.
• W2108974407 date "1998-03-01" @default.
• W2108974407 modified "2023-10-03" @default.
• W2108974407 title "Randomised placebo-controlled study of atovaquone plus proguanil for malaria prophylaxis in children" @default.
• W2108974407 cites W1935016814 @default.
• W2108974407 cites W2007561244 @default.
• W2108974407 cites W2025781604 @default.
• W2108974407 cites W2041866493 @default.
• W2108974407 cites W2046836167 @default.
• W2108974407 cites W2066217974 @default.
• W2108974407 cites W2068125083 @default.
• W2108974407 cites W2081638505 @default.
• W2108974407 cites W2085832074 @default.
• W2108974407 cites W2104697202 @default.
• W2108974407 cites W2122681961 @default.
• W2108974407 cites W2132460175 @default.
• W2108974407 cites W2155973203 @default.
• W2108974407 cites W2161090482 @default.
• W2108974407 cites W2282740767 @default.
• W2108974407 cites W2325187735 @default.
• W2108974407 cites W2613774928 @default.
• W2108974407 cites W3149503781 @default.
• W2108974407 doi "https://doi.org/10.1016/s0140-6736(97)09222-2" @default.
• W2108974407 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9504515" @default.
• W2108974407 hasPublicationYear "1998" @default.
• W2108974407 type Work @default.
• W2108974407 sameAs 2108974407 @default.
• W2108974407 citedByCount "122" @default.
• W2108974407 countsByYear W21089744072012 @default.
• W2108974407 countsByYear W21089744072013 @default.
• W2108974407 countsByYear W21089744072014 @default.
• W2108974407 countsByYear W21089744072015 @default.
• W2108974407 countsByYear W21089744072017 @default.
• W2108974407 countsByYear W21089744072018 @default.
• W2108974407 countsByYear W21089744072019 @default.
• W2108974407 countsByYear W21089744072020 @default.
• W2108974407 countsByYear W21089744072021 @default.
• W2108974407 countsByYear W21089744072022 @default.
• W2108974407 crossrefType "journal-article" @default.
• W2108974407 hasAuthorship W2108974407A5025601117 @default.
• W2108974407 hasAuthorship W2108974407A5043369631 @default.
• W2108974407 hasAuthorship W2108974407A5044133610 @default.
• W2108974407 hasAuthorship W2108974407A5087769443 @default.
• W2108974407 hasAuthorship W2108974407A5090444000 @default.
• W2108974407 hasConcept C126322002 @default.
• W2108974407 hasConcept C141071460 @default.
• W2108974407 hasConcept C142724271 @default.
• W2108974407 hasConcept C197934379 @default.
• W2108974407 hasConcept C203014093 @default.
• W2108974407 hasConcept C203092338 @default.
• W2108974407 hasConcept C204787440 @default.
• W2108974407 hasConcept C27081682 @default.
• W2108974407 hasConcept C2778048844 @default.
• W2108974407 hasConcept C2778371730 @default.
• W2108974407 hasConcept C2779124865 @default.
• W2108974407 hasConcept C2779142074 @default.
• W2108974407 hasConcept C2779636613 @default.
• W2108974407 hasConcept C535046627 @default.
• W2108974407 hasConcept C71924100 @default.
• W2108974407 hasConceptScore W2108974407C126322002 @default.
• W2108974407 hasConceptScore W2108974407C141071460 @default.
• W2108974407 hasConceptScore W2108974407C142724271 @default.
• W2108974407 hasConceptScore W2108974407C197934379 @default.
• W2108974407 hasConceptScore W2108974407C203014093 @default.
• W2108974407 hasConceptScore W2108974407C203092338 @default.
• W2108974407 hasConceptScore W2108974407C204787440 @default.
• W2108974407 hasConceptScore W2108974407C27081682 @default.
• W2108974407 hasConceptScore W2108974407C2778048844 @default.
• W2108974407 hasConceptScore W2108974407C2778371730 @default.
• W2108974407 hasConceptScore W2108974407C2779124865 @default.
• W2108974407 hasConceptScore W2108974407C2779142074 @default.
• W2108974407 hasConceptScore W2108974407C2779636613 @default.
• W2108974407 hasConceptScore W2108974407C535046627 @default.
• W2108974407 hasConceptScore W2108974407C71924100 @default.
• W2108974407 hasIssue "9104" @default.
• W2108974407 hasLocation W21089744071 @default.
• W2108974407 hasLocation W21089744072 @default.
• W2108974407 hasOpenAccess W2108974407 @default.
• W2108974407 hasPrimaryLocation W21089744071 @default.
• W2108974407 hasRelatedWork W1901559508 @default.
• W2108974407 hasRelatedWork W1983326303 @default.
• W2108974407 hasRelatedWork W2000230526 @default.
• W2108974407 hasRelatedWork W2016307598 @default.
• W2108974407 hasRelatedWork W2028779415 @default.
• W2108974407 hasRelatedWork W2042545334 @default.
• W2108974407 hasRelatedWork W2156134301 @default.
• W2108974407 hasRelatedWork W2168903926 @default.
• W2108974407 hasRelatedWork W2735276193 @default.
• W2108974407 hasRelatedWork W2805546692 @default.
• W2108974407 hasVolume "351" @default.
• W2108974407 isParatext "false" @default.
• W2108974407 isRetracted "false" @default.

• next