FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2108999119> ?p ?o ?g. }

• W2108999119 endingPage "933" @default.
• W2108999119 startingPage "921" @default.
• W2108999119 abstract "Cilia and flagella are highly conserved microtubule (MT)-based organelles with motile and sensory functions, and ciliary defects have been linked to several human diseases. The 9 + 2 structure of motile axonemes contains nine MT doublets interconnected by nexin links, which surround a central pair of singlet MTs. Motility is generated by the orchestrated activity of thousands of dynein motors, which drive interdoublet sliding. A key regulator of motor activity is the dynein regulatory complex (DRC), but detailed structural information is lacking. Using cryoelectron tomography of wild-type and mutant axonemes from Chlamydomonas reinhardtii, we visualized the DRC in situ at molecular resolution. We present the three-dimensional structure of the DRC, including a model for its subunit organization and intermolecular connections that establish the DRC as a major regulatory node. We further demonstrate that the DRC is the nexin link, which is thought to be critical for the generation of axonemal bending." @default.
• W2108999119 created "2016-06-24" @default.
• W2108999119 creator A5000183079 @default.
• W2108999119 creator A5006903111 @default.
• W2108999119 creator A5042781820 @default.
• W2108999119 creator A5077466166 @default.
• W2108999119 creator A5090207591 @default.
• W2108999119 date "2009-12-14" @default.
• W2108999119 modified "2023-10-01" @default.
• W2108999119 title "The dynein regulatory complex is the nexin link and a major regulatory node in cilia and flagella" @default.
• W2108999119 cites W1964729377 @default.
• W2108999119 cites W1974483160 @default.
• W2108999119 cites W1987395875 @default.
• W2108999119 cites W1992536427 @default.
• W2108999119 cites W1999005418 @default.
• W2108999119 cites W2000467705 @default.
• W2108999119 cites W2016617586 @default.
• W2108999119 cites W2017068376 @default.
• W2108999119 cites W2028370365 @default.
• W2108999119 cites W2028605946 @default.
• W2108999119 cites W2029101220 @default.
• W2108999119 cites W2033925514 @default.
• W2108999119 cites W2034269295 @default.
• W2108999119 cites W2043738037 @default.
• W2108999119 cites W2051255332 @default.
• W2108999119 cites W2053451392 @default.
• W2108999119 cites W2061360656 @default.
• W2108999119 cites W2072169699 @default.
• W2108999119 cites W2075115399 @default.
• W2108999119 cites W2079566817 @default.
• W2108999119 cites W2084646195 @default.
• W2108999119 cites W2091432967 @default.
• W2108999119 cites W2094703169 @default.
• W2108999119 cites W2094869942 @default.
• W2108999119 cites W2094909610 @default.
• W2108999119 cites W2105150568 @default.
• W2108999119 cites W2119763712 @default.
• W2108999119 cites W2122280790 @default.
• W2108999119 cites W2132629607 @default.
• W2108999119 cites W2132814566 @default.
• W2108999119 cites W2137007077 @default.
• W2108999119 cites W2139175710 @default.
• W2108999119 cites W2140116901 @default.
• W2108999119 cites W2142161929 @default.
• W2108999119 cites W2142521689 @default.
• W2108999119 cites W2145778422 @default.
• W2108999119 cites W2147443197 @default.
• W2108999119 cites W2148655168 @default.
• W2108999119 cites W2148958327 @default.
• W2108999119 cites W2151312504 @default.
• W2108999119 cites W2154261437 @default.
• W2108999119 cites W2157067561 @default.
• W2108999119 cites W2157320939 @default.
• W2108999119 cites W2160266887 @default.
• W2108999119 cites W2164405998 @default.
• W2108999119 cites W2171348212 @default.
• W2108999119 cites W2394598198 @default.
• W2108999119 cites W2405465017 @default.
• W2108999119 cites W2746196359 @default.
• W2108999119 cites W4229933927 @default.
• W2108999119 doi "https://doi.org/10.1083/jcb.200908067" @default.
• W2108999119 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2806320" @default.
• W2108999119 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20008568" @default.
• W2108999119 hasPublicationYear "2009" @default.
• W2108999119 type Work @default.
• W2108999119 sameAs 2108999119 @default.
• W2108999119 citedByCount "292" @default.
• W2108999119 countsByYear W21089991192012 @default.
• W2108999119 countsByYear W21089991192013 @default.
• W2108999119 countsByYear W21089991192014 @default.
• W2108999119 countsByYear W21089991192015 @default.
• W2108999119 countsByYear W21089991192016 @default.
• W2108999119 countsByYear W21089991192017 @default.
• W2108999119 countsByYear W21089991192018 @default.
• W2108999119 countsByYear W21089991192019 @default.
• W2108999119 countsByYear W21089991192020 @default.
• W2108999119 countsByYear W21089991192021 @default.
• W2108999119 countsByYear W21089991192022 @default.
• W2108999119 countsByYear W21089991192023 @default.
• W2108999119 crossrefType "journal-article" @default.
• W2108999119 hasAuthorship W2108999119A5000183079 @default.
• W2108999119 hasAuthorship W2108999119A5006903111 @default.
• W2108999119 hasAuthorship W2108999119A5042781820 @default.
• W2108999119 hasAuthorship W2108999119A5077466166 @default.
• W2108999119 hasAuthorship W2108999119A5090207591 @default.
• W2108999119 hasBestOaLocation W21089991191 @default.
• W2108999119 hasConcept C100094513 @default.
• W2108999119 hasConcept C104317684 @default.
• W2108999119 hasConcept C106987784 @default.
• W2108999119 hasConcept C115811362 @default.
• W2108999119 hasConcept C143065580 @default.
• W2108999119 hasConcept C20418707 @default.
• W2108999119 hasConcept C24870808 @default.
• W2108999119 hasConcept C2776580309 @default.
• W2108999119 hasConcept C2777727519 @default.
• W2108999119 hasConcept C2910722709 @default.
• W2108999119 hasConcept C37590093 @default.
• W2108999119 hasConcept C54355233 @default.

• next