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- W2109006512 abstract "This article is part of a Special Issue Parental Care. It is becoming clear that the female brain has an inherent plasticity that is expressed during reproduction. The changes that occur benefit the offspring, which in turn secures the survival of the mother's genetic legacy. Thus, the onset of maternal motivation involves basic mechanisms from genetic expression profiles, to hormone release, to hormone-neuron interactions, all of which fundamentally change the neural architecture - and for a period of time that extends, interestingly, beyond the reproductive life of the female. Although multiple brain areas involved in maternal responses are discussed, this review focuses primarily on plasticity in the maternal hippocampus during pregnancy, the postpartum period and well into aging as it pertains to changes in cognition. In addition, the effects of prolonged and repeated stress on these dynamic responses are considered. The maternal brain is a marvel of directed change, extending into behaviors both obvious (infant-directed) and less obvious (predation, cognition). In sum, the far-reaching effects of reproduction on the female nervous system provide an opportunity to investigate neuroplasticity and behavioral flexibility in a natural mammalian model." @default.
- W2109006512 created "2016-06-24" @default.
- W2109006512 creator A5018644793 @default.
- W2109006512 creator A5076114965 @default.
- W2109006512 creator A5079191166 @default.
- W2109006512 date "2016-01-01" @default.
- W2109006512 modified "2023-10-14" @default.
- W2109006512 title "Neuroplasticity in the maternal hippocampus: Relation to cognition and effects of repeated stress" @default.
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