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• W2109011187 abstract "Many mitochondrial and plastid protein complexes contain subunits that are encoded in different genomes. In animals, nuclear-encoded mitochondrial proteins often exhibit rapid sequence evolution, which has been hypothesized to result from selection for mutations that compensate for changes in interacting subunits encoded in mutation-prone animal mitochondrial DNA. To test this hypothesis, we analyzed nuclear genes encoding cytosolic and organelle ribosomal proteins in flowering plants. The model angiosperm genus Arabidopsis exhibits low organelle mutation rates, typical of most plants. Nevertheless, we found that (nuclear-encoded) subunits of organelle ribosomes in Arabidopsis have higher amino acid sequence polymorphism and divergence than their counterparts in cytosolic ribosomes, suggesting that organelle ribosomes experience relaxed functional constraint. However, the observed difference between organelle and cytosolic ribosomes was smaller than in animals and could be partially attributed to rapid evolution in N-terminal organelle-targeting peptides that are not involved in ribosome function. To test the role of organelle mutation more directly, we used transcriptomic data from an angiosperm genus (Silene) with highly variable rates of organelle genome evolution. We found that Silene species with unusually fast-evolving mitochondrial and plastid DNA exhibited increased amino acid sequence divergence in ribosomal proteins targeted to the organelles but not in those that function in cytosolic ribosomes. Overall, these findings support the hypothesis that rapid organelle genome evolution has selected for compensatory mutations in nuclear-encoded proteins. We conclude that coevolution between interacting subunits encoded in different genomic compartments within the eukaryotic cell is an important determinant of variation in rates of protein sequence evolution." @default.
• W2109011187 created "2016-06-24" @default.
• W2109011187 creator A5043942506 @default.
• W2109011187 creator A5071654439 @default.
• W2109011187 creator A5075481031 @default.
• W2109011187 creator A5088633211 @default.
• W2109011187 date "2013-12-13" @default.
• W2109011187 modified "2023-09-30" @default.
• W2109011187 title "Cytonuclear Interactions and Relaxed Selection Accelerate Sequence Evolution in Organelle Ribosomes" @default.
• W2109011187 cites W188761360 @default.
• W2109011187 cites W1915142853 @default.
• W2109011187 cites W1963919199 @default.
• W2109011187 cites W1964343732 @default.
• W2109011187 cites W1967390196 @default.
• W2109011187 cites W1967598050 @default.
• W2109011187 cites W1976210008 @default.
• W2109011187 cites W1976247738 @default.
• W2109011187 cites W1982603712 @default.
• W2109011187 cites W1989831436 @default.
• W2109011187 cites W1991517396 @default.
• W2109011187 cites W1996515220 @default.
• W2109011187 cites W2004146038 @default.
• W2109011187 cites W2004694067 @default.
• W2109011187 cites W2004746898 @default.
• W2109011187 cites W2006786379 @default.
• W2109011187 cites W2016710702 @default.
• W2109011187 cites W2016718974 @default.
• W2109011187 cites W2016952838 @default.
• W2109011187 cites W2020792219 @default.
• W2109011187 cites W2023853020 @default.
• W2109011187 cites W2024239836 @default.
• W2109011187 cites W2024745007 @default.
• W2109011187 cites W2035933706 @default.
• W2109011187 cites W2039959586 @default.
• W2109011187 cites W2051500083 @default.
• W2109011187 cites W2057171606 @default.
• W2109011187 cites W2063732750 @default.
• W2109011187 cites W2064622956 @default.
• W2109011187 cites W2066307121 @default.
• W2109011187 cites W2075436975 @default.
• W2109011187 cites W2078638028 @default.
• W2109011187 cites W2085073376 @default.
• W2109011187 cites W2088424584 @default.
• W2109011187 cites W2089047063 @default.
• W2109011187 cites W2091449337 @default.
• W2109011187 cites W2093905196 @default.
• W2109011187 cites W2096022605 @default.
• W2109011187 cites W2097341408 @default.
• W2109011187 cites W2098525777 @default.
• W2109011187 cites W2101405811 @default.
• W2109011187 cites W2103170242 @default.
• W2109011187 cites W2103809514 @default.
• W2109011187 cites W2103997560 @default.
• W2109011187 cites W2104099887 @default.
• W2109011187 cites W2104952200 @default.
• W2109011187 cites W2105772341 @default.
• W2109011187 cites W2110188639 @default.
• W2109011187 cites W2110335151 @default.
• W2109011187 cites W2115148114 @default.
• W2109011187 cites W2117056672 @default.
• W2109011187 cites W2124727354 @default.
• W2109011187 cites W2125865118 @default.
• W2109011187 cites W2126419817 @default.
• W2109011187 cites W2127377335 @default.
• W2109011187 cites W2127735379 @default.
• W2109011187 cites W2130190479 @default.
• W2109011187 cites W2130680472 @default.
• W2109011187 cites W2130871092 @default.
• W2109011187 cites W2132632499 @default.
• W2109011187 cites W2132926880 @default.
• W2109011187 cites W2137342307 @default.
• W2109011187 cites W2140002278 @default.
• W2109011187 cites W2141292707 @default.
• W2109011187 cites W2145406188 @default.
• W2109011187 cites W2147322476 @default.
• W2109011187 cites W2148608476 @default.
• W2109011187 cites W2151068319 @default.
• W2109011187 cites W2151624523 @default.
• W2109011187 cites W2152195140 @default.
• W2109011187 cites W2154584207 @default.
• W2109011187 cites W2156150100 @default.
• W2109011187 cites W2157406319 @default.
• W2109011187 cites W2167024615 @default.
• W2109011187 cites W2168144637 @default.
• W2109011187 cites W2169940135 @default.
• W2109011187 cites W4232591682 @default.
• W2109011187 cites W4233127534 @default.
• W2109011187 cites W4235054736 @default.
• W2109011187 cites W4237559319 @default.
• W2109011187 cites W4253572634 @default.
• W2109011187 cites W91518616 @default.
• W2109011187 doi "https://doi.org/10.1093/molbev/mst259" @default.
• W2109011187 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24336923" @default.
• W2109011187 hasPublicationYear "2013" @default.
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