Matches in SemOpenAlex for { <https://semopenalex.org/work/W2109021184> ?p ?o ?g. }
- W2109021184 abstract "Obstructive sleep apnea syndrome (OSAS) is a highly prevalent medical disorder affecting at least 4% of men and 2% of women in the developed world. The disorder is characterized by repeated episodes of pharyngeal obstruction during sleep that lead to intermittent hypoxia, sleep fragmentation, and excessive daytime sleepiness. OSAS is associated with significant morbidity and mortality. The excessive daytime sleepiness leads to impairments in quality of life, cognitive performance, and social functioning. The major health burden in OSAS patients, however, is the strong risk of cardiovascular diseases, such as systemic arterial hypertension, coronary artery disease, heart failure, and stroke. The association between OSAS and cardiovascular diseases has been suggested for many years, and more recently is corroborated by large-scale epidemiologic and prospective studies. The underlying mechanisms mediating this association are incompletely understood, but the pathogenesis is likely to be a multifactorial process. In recent years, considerable effort has been made to understand the contribution of genetic factors to the development of OSAS involving genome-wide linkage studies and association" @default.
- W2109021184 created "2016-06-24" @default.
- W2109021184 creator A5036094687 @default.
- W2109021184 creator A5050223446 @default.
- W2109021184 creator A5065594704 @default.
- W2109021184 date "2011-06-01" @default.
- W2109021184 modified "2023-09-26" @default.
- W2109021184 title "Genetics of Cardiovascular Consequences of Obstructive Sleep Apnea Syndrome" @default.
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