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- W2109071188 abstract "Summary Allergic rhinitis is a highly prevalent respiratory disease, affecting up to 40% of the population in some countries, and has an important impact on quality of life. Although a number of different drug types are available for treating allergic rhinitis, antihistamines are currently considered first‐line therapy. Newer antihistamines, such as fexofenadine, are very effective in suppressing symptoms and are largely free of side‐effects. In addition, they have been shown to improve patient's quality of life. Some patients have residual symptoms despite the use of antihistamines and other available treatments. Moreover, most current treatments only relieve symptoms, and do not modify the course of the disease. Current research into the pathophysiology of the disease is opening many promising new avenues for improved treatments. Such possibilities include improving methods of immunotherapy, based on our greater understanding of the balance between Th1 and Th2 cells and of the cytokines that they produce; and targeting and blocking the effects of bradykinin, substance P, leukotrienes, IgE antibody, tryptase, platelet‐activating factor and prostaglandins. Refinements of immunotherapy are particularly promising, as they may provide a permanent cure for the disease in an increasing number of patients. Furthermore, recent evidence has shown that early intervention in children with allergic rhinitis, by antihistamine treatment or immunotherapy, can reduce the risk of developing asthma. Improved understanding of the links between allergic rhinitis and asthma is likely to advance the treatment of both diseases." @default.
- W2109071188 created "2016-06-24" @default.
- W2109071188 creator A5006674601 @default.
- W2109071188 creator A5012461623 @default.
- W2109071188 creator A5041034753 @default.
- W2109071188 date "2002-07-18" @default.
- W2109071188 modified "2023-10-18" @default.
- W2109071188 title "Allergic rhinitis: current and future treatments" @default.
- W2109071188 cites W122478359 @default.
- W2109071188 cites W1510464094 @default.
- W2109071188 cites W1606896194 @default.
- W2109071188 cites W1882224927 @default.
- W2109071188 cites W1929149355 @default.
- W2109071188 cites W1964226776 @default.
- W2109071188 cites W1970342398 @default.
- W2109071188 cites W1970648068 @default.
- W2109071188 cites W1971393493 @default.
- W2109071188 cites W1971798215 @default.
- W2109071188 cites W1973319846 @default.
- W2109071188 cites W1975248566 @default.
- W2109071188 cites W1981629928 @default.
- W2109071188 cites W1988664394 @default.
- W2109071188 cites W1994145602 @default.
- W2109071188 cites W1994157850 @default.
- W2109071188 cites W1995104897 @default.
- W2109071188 cites W1995632739 @default.
- W2109071188 cites W1997155157 @default.
- W2109071188 cites W1998913833 @default.
- W2109071188 cites W1999909589 @default.
- W2109071188 cites W2000088332 @default.
- W2109071188 cites W2000134951 @default.
- W2109071188 cites W2000931511 @default.
- W2109071188 cites W2001316705 @default.
- W2109071188 cites W2001450061 @default.
- W2109071188 cites W2001662633 @default.
- W2109071188 cites W2002614529 @default.
- W2109071188 cites W2008476832 @default.
- W2109071188 cites W2012177076 @default.
- W2109071188 cites W2012200648 @default.
- W2109071188 cites W2012785799 @default.
- W2109071188 cites W2016191225 @default.
- W2109071188 cites W2016700982 @default.
- W2109071188 cites W2018088497 @default.
- W2109071188 cites W2018392434 @default.
- W2109071188 cites W2019610734 @default.
- W2109071188 cites W2019856184 @default.
- W2109071188 cites W2019951901 @default.
- W2109071188 cites W2020883725 @default.
- W2109071188 cites W2021654803 @default.
- W2109071188 cites W2022267899 @default.
- W2109071188 cites W2023408214 @default.
- W2109071188 cites W2033211028 @default.
- W2109071188 cites W2033232206 @default.
- W2109071188 cites W2034466538 @default.
- W2109071188 cites W2038382554 @default.
- W2109071188 cites W2038687074 @default.
- W2109071188 cites W2039983513 @default.
- W2109071188 cites W2045428837 @default.
- W2109071188 cites W2045682600 @default.
- W2109071188 cites W2047251211 @default.
- W2109071188 cites W2051167659 @default.
- W2109071188 cites W2051814728 @default.
- W2109071188 cites W2053194248 @default.
- W2109071188 cites W2053231991 @default.
- W2109071188 cites W2053591346 @default.
- W2109071188 cites W2058274677 @default.
- W2109071188 cites W2059326505 @default.
- W2109071188 cites W2060607460 @default.
- W2109071188 cites W2061564002 @default.
- W2109071188 cites W2063390971 @default.
- W2109071188 cites W2068797688 @default.
- W2109071188 cites W2072883273 @default.
- W2109071188 cites W2078111263 @default.
- W2109071188 cites W2080515725 @default.
- W2109071188 cites W2086363430 @default.
- W2109071188 cites W2087405409 @default.
- W2109071188 cites W2090178093 @default.
- W2109071188 cites W2090625779 @default.
- W2109071188 cites W2090846163 @default.
- W2109071188 cites W2092465845 @default.
- W2109071188 cites W2092481568 @default.
- W2109071188 cites W2093718671 @default.
- W2109071188 cites W2094125657 @default.
- W2109071188 cites W2094983249 @default.
- W2109071188 cites W2096210343 @default.
- W2109071188 cites W2097877025 @default.
- W2109071188 cites W2103665631 @default.
- W2109071188 cites W2106098629 @default.
- W2109071188 cites W2108630923 @default.
- W2109071188 cites W2116838130 @default.
- W2109071188 cites W2121422859 @default.
- W2109071188 cites W2121872020 @default.
- W2109071188 cites W2130614990 @default.
- W2109071188 cites W2131861902 @default.
- W2109071188 cites W2137487999 @default.
- W2109071188 cites W2138879259 @default.
- W2109071188 cites W2141229428 @default.
- W2109071188 cites W2146572433 @default.