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• W2109077420 abstract "No AccessJournal of UrologyPediatric Urology1 Sep 2011Unilateral Multicystic Dysplastic Kidney With Progressive Infundibular Stenosis in the Contralateral Kidney: Experience at 1 Center and Review of Literature E.A. Dally, A. Raman, N.R. Webb, and R.H. Farnsworth E.A. DallyE.A. Dally More articles by this author , A. RamanA. Raman More articles by this author , N.R. WebbN.R. Webb More articles by this author , and R.H. FarnsworthR.H. Farnsworth More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2011.05.001AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: We analyzed the association between unilateral multicystic dysplastic kidney and subsequent contralateral infundibular stenosis, which can result in progressive calyceal dilatation, and has been linked to global hyperfiltration injury and renal impairment. Materials and Methods: During the last 10 years 200 children presented with unilateral multicystic dysplastic kidney. Of these children 5 subsequently exhibited contralateral infundibular stenosis. We reviewed the published data on multicystic dysplastic kidney as well as infundibular stenosis to examine this association further. Results: Three patients underwent open surgical exploration since rapid progression with associated parenchymal thinning was detected. Literature review failed to identify any discussion of infundibular stenosis in studies focusing on long-term followup of children with a unilateral multicystic dysplastic kidney. Several case reports and case series discuss this condition in association with other collecting system anomalies. However, these anomalies are hypothesized to be part of a disease spectrum resulting from aberrant formation of the collecting system. Bilateral involvement has been reported in fewer than 10 cases. Conclusions: Our cases represent a part of the spectrum of pyelocalyceal dysgenesis that can have bilateral involvement of varying degrees. Of particular concern was the delayed presentation in some of our patients and the progressive nature of the lesions. Although exceedingly rare, we wish to highlight the association of multicystic dysplastic kidney and progressive infundibular stenosis of the contralateral kidney and renal impairment. References 1 : Clinical course and outcome for children with multicystic dysplastic kidneys. Pediatr Nephrol2000; 14: 1098. Google Scholar 2 : Unilateral multicystic dysplastic kidney: experience in children. BJU Int2004; 93: 388. Google Scholar 3 : Non-surgical management of the multicystic dysplastic kidney. BJU Int2008; 101: 804. Google Scholar 4 : Unilateral multicystic dysplastic kidney: a meta-analysis of observational studies on the incidence, associated urinary tract malformations and the contralateral kidney. 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Link, Google Scholar 20 : Infundibulopelvic stenosis: a long-term followup. J Urol1994; 152: 837. Abstract, Google Scholar 21 : Infundibulopelvic stenosis, multicystic kidney, and calyectasis in a kindred: clinical observations and genetic analysis. Am J Med Genet1995; 59: 218. Google Scholar 22 : . Paris: JB Bailliere1841: 507. Google Scholar 23 : Hydrocalycosis. J Urol1949; 62: 206. Link, Google Scholar 24 : Infundibulopelvic stenosis in children. AJR Am J Roentgenol1984; 142: 471. Google Scholar Sydney Children's Hospital Randwick, Sydney, Australia© 2011 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 186Issue 3September 2011Page: 1053-1058 Advertisement Copyright & Permissions© 2011 by American Urological Association Education and Research, Inc.Keywordskidney pelvismulticystic dysplastic kidneypathologicconstrictionkidney calicesMetricsAuthor Information E.A. Dally More articles by this author A. Raman More articles by this author N.R. Webb More articles by this author R.H. Farnsworth More articles by this author Expand All Advertisement PDF downloadLoading ..." @default.
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• W2109077420 title "Unilateral Multicystic Dysplastic Kidney With Progressive Infundibular Stenosis in the Contralateral Kidney: Experience at 1 Center and Review of Literature" @default.
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