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• W2109094934 abstract "Abstract We present a brief summary of the key factors underlying protein structure, as developed in the investigations of Pauling, Ramachandran, and Rose. We then outline a simplified physical model of proteins that focusses on geometry and symmetry. Although this model superficially appears unrelated to the detailed chemical descriptions commonly applied to proteins, we show that it captures the essential elements of the chemistry and provides a unified framework for understanding the common characteristics of folded proteins. We suggest that the spectrum of protein native state structures is determined by geometry and symmetry and the role of the sequence is to choose its native state structure from this predetermined menu. Proteins 2006. © 2006 Wiley‐Liss, Inc." @default.
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• W2109094934 date "2006-02-09" @default.
• W2109094934 modified "2023-09-25" @default.
• W2109094934 title "What determines the spectrum of protein native state structures?" @default.
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• W2109094934 doi "https://doi.org/10.1002/prot.20869" @default.
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