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- W2109122371 abstract "In this study the authors have conducted experiments to determine if oligonucleotides containing terminal thiol groups can be used, in the presence of Cu+2, to cut single- and double-stranded DNA molecules adjacent to the oligonucleotide binding site. The results of these experiments demonstrate that these modified oligonucleotides cleave DNA in the presence of Cu+2, but the reaction could not be controlled sufficiently to attain site-selective cleavage or minimize degradation of the thiol terminated oligonucleotide." @default.
- W2109122371 created "2016-06-24" @default.
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- W2109122371 date "1996-06-01" @default.
- W2109122371 modified "2023-09-27" @default.
- W2109122371 title "Testing of thiol-terminated oligonucleotides as potential DNA-cleaving reagents" @default.
- W2109122371 doi "https://doi.org/10.2172/270720" @default.
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