Matches in SemOpenAlex for { <https://semopenalex.org/work/W2109131620> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W2109131620 endingPage "558" @default.
- W2109131620 startingPage "549" @default.
- W2109131620 abstract "Fenfluramine was administered to 14 outpatients with the syndrome of autism in a double blind crossover study (ABA design) to determine its effects on blood serotonin concentrations, platelet counts, and symptomatic behaviors. Blood serotonin concentrations decreased an average of 51% after 1 month on medication and returned to baseline levels within 1 month after return to placebo. Platelet counts were unaffected. Serial observation scales, developmental profiles, intelligence scales, and parental interviews and diaries were obtained. They revealed that certain symptoms improved significantly while patients were on medication and worsened when placebo was reinstituted. Patients with both normal and elevated baseline serotonin had symptomatic improvements. No adverse reactions to medication nor clinically significant side effects were noted. Definitive conclusions regarding relationships among initial serotonin levels, clinical features, and symptom responses cannot yet be drawn since data are available on only 14 patients. The encouraging findings in these 14 patients are being studied further at 18 medical centers throughout the United States on approximately 150 patients." @default.
- W2109131620 created "2016-06-24" @default.
- W2109131620 creator A5049820453 @default.
- W2109131620 creator A5057554539 @default.
- W2109131620 creator A5069738442 @default.
- W2109131620 creator A5073727384 @default.
- W2109131620 date "1983-11-01" @default.
- W2109131620 modified "2023-10-18" @default.
- W2109131620 title "Effects of Fenfluramine on 14 Outpatients with the Syndrome of Autism" @default.
- W2109131620 cites W1963676567 @default.
- W2109131620 cites W1978231228 @default.
- W2109131620 cites W1983858278 @default.
- W2109131620 cites W1986819113 @default.
- W2109131620 cites W1993637431 @default.
- W2109131620 cites W2000567993 @default.
- W2109131620 cites W2007900188 @default.
- W2109131620 cites W2015451879 @default.
- W2109131620 cites W2018617764 @default.
- W2109131620 cites W2020248944 @default.
- W2109131620 cites W2031385438 @default.
- W2109131620 cites W2051904748 @default.
- W2109131620 cites W2066103312 @default.
- W2109131620 cites W2083394334 @default.
- W2109131620 cites W2113395965 @default.
- W2109131620 cites W3028358862 @default.
- W2109131620 doi "https://doi.org/10.1097/00004583-198311000-00006" @default.
- W2109131620 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6655169" @default.
- W2109131620 hasPublicationYear "1983" @default.
- W2109131620 type Work @default.
- W2109131620 sameAs 2109131620 @default.
- W2109131620 citedByCount "108" @default.
- W2109131620 crossrefType "journal-article" @default.
- W2109131620 hasAuthorship W2109131620A5049820453 @default.
- W2109131620 hasAuthorship W2109131620A5057554539 @default.
- W2109131620 hasAuthorship W2109131620A5069738442 @default.
- W2109131620 hasAuthorship W2109131620A5073727384 @default.
- W2109131620 hasConcept C118552586 @default.
- W2109131620 hasConcept C126322002 @default.
- W2109131620 hasConcept C142724271 @default.
- W2109131620 hasConcept C15744967 @default.
- W2109131620 hasConcept C170493617 @default.
- W2109131620 hasConcept C187212893 @default.
- W2109131620 hasConcept C197934379 @default.
- W2109131620 hasConcept C204787440 @default.
- W2109131620 hasConcept C205778803 @default.
- W2109131620 hasConcept C27081682 @default.
- W2109131620 hasConcept C2775864247 @default.
- W2109131620 hasConcept C2779638493 @default.
- W2109131620 hasConcept C42219234 @default.
- W2109131620 hasConcept C535046627 @default.
- W2109131620 hasConcept C71924100 @default.
- W2109131620 hasConcept C87813604 @default.
- W2109131620 hasConcept C89560881 @default.
- W2109131620 hasConceptScore W2109131620C118552586 @default.
- W2109131620 hasConceptScore W2109131620C126322002 @default.
- W2109131620 hasConceptScore W2109131620C142724271 @default.
- W2109131620 hasConceptScore W2109131620C15744967 @default.
- W2109131620 hasConceptScore W2109131620C170493617 @default.
- W2109131620 hasConceptScore W2109131620C187212893 @default.
- W2109131620 hasConceptScore W2109131620C197934379 @default.
- W2109131620 hasConceptScore W2109131620C204787440 @default.
- W2109131620 hasConceptScore W2109131620C205778803 @default.
- W2109131620 hasConceptScore W2109131620C27081682 @default.
- W2109131620 hasConceptScore W2109131620C2775864247 @default.
- W2109131620 hasConceptScore W2109131620C2779638493 @default.
- W2109131620 hasConceptScore W2109131620C42219234 @default.
- W2109131620 hasConceptScore W2109131620C535046627 @default.
- W2109131620 hasConceptScore W2109131620C71924100 @default.
- W2109131620 hasConceptScore W2109131620C87813604 @default.
- W2109131620 hasConceptScore W2109131620C89560881 @default.
- W2109131620 hasIssue "6" @default.
- W2109131620 hasLocation W21091316201 @default.
- W2109131620 hasLocation W21091316202 @default.
- W2109131620 hasOpenAccess W2109131620 @default.
- W2109131620 hasPrimaryLocation W21091316201 @default.
- W2109131620 hasRelatedWork W1988605464 @default.
- W2109131620 hasRelatedWork W1996033496 @default.
- W2109131620 hasRelatedWork W1997746821 @default.
- W2109131620 hasRelatedWork W2042004687 @default.
- W2109131620 hasRelatedWork W2053346013 @default.
- W2109131620 hasRelatedWork W2079307218 @default.
- W2109131620 hasRelatedWork W2080052513 @default.
- W2109131620 hasRelatedWork W2245786917 @default.
- W2109131620 hasRelatedWork W2409823978 @default.
- W2109131620 hasRelatedWork W2423674550 @default.
- W2109131620 hasVolume "22" @default.
- W2109131620 isParatext "false" @default.
- W2109131620 isRetracted "false" @default.
- W2109131620 magId "2109131620" @default.
- W2109131620 workType "article" @default.