FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2109132899> ?p ?o ?g. }

• W2109132899 endingPage "1080" @default.
• W2109132899 startingPage "1074" @default.
• W2109132899 abstract "An early diagnosis in patients presenting with arthritis is important to provide information about prognosis and to initiate treatment. The objective of this study was to determine which markers applied in immunohistological analysis of synovial tissue (ST) specimens could be used to differentiate rheumatoid arthritis (RA) from other forms of arthritis.Synovial biopsies were obtained by blind needle techniques from 95 patients with early arthritis. After follow-up of at least 2 yr to verify the diagnosis, the patients could be classified as follows: RA (n=36), undifferentiated arthritis (UA; n=21), osteoarthritis (OA; n=17), reactive arthritis (ReA; n=10), ankylosing spondylitis (AS; n=3), psoriatic arthritis (PsA; n=2) and crystal-induced arthritis (CA; n=6). ST sections were analysed by immunohistochemistry using monoclonal antibodies against CD3, CD4, CD8, CD22 (B cells), CD38 (plasma cells), CD68 (macrophages) and CD55 (fibroblast-like synoviocytes).Logistic regression analysis revealed that the higher scores for the numbers of CD38+ plasma cells and CD22+ B cells in RA were the best discriminating markers comparing RA to non-RA patients (CD38: P=0.0001; CD22: P<0.05). Polychotomous regression analysis comparing three diagnostic categories (1: RA; 2: UA, ReA, AS and PsA; 3: OA and CA) also identified the score for the number of CD38+ plasma cells (P<0.0001) as well as the numbers of CD68+ macrophages in the synovial sublining (P=0.05) as discriminating markers.The results suggest that immunohistochemical analysis of ST specimens from early arthritis patients can be used to differentiate RA from non-RA patients. The numbers of plasma cells, B cells and macrophages are especially increased in ST of patients with RA. Future studies in early arthritis patients with clinical features which do not allow an immediate confident diagnosis may clarify the role of this test system in differential diagnosis." @default.
• W2109132899 created "2016-06-24" @default.
• W2109132899 creator A5001031394 @default.
• W2109132899 creator A5008292605 @default.
• W2109132899 creator A5012564728 @default.
• W2109132899 creator A5047229092 @default.
• W2109132899 creator A5052424289 @default.
• W2109132899 creator A5084807129 @default.
• W2109132899 date "1999-11-01" @default.
• W2109132899 modified "2023-10-17" @default.
• W2109132899 title "Immunohistological analysis of synovial tissue for differential diagnosis in early arthritis" @default.
• W2109132899 cites W1968619512 @default.
• W2109132899 cites W1971984690 @default.
• W2109132899 cites W1977546841 @default.
• W2109132899 cites W1977767565 @default.
• W2109132899 cites W1984663399 @default.
• W2109132899 cites W2004992321 @default.
• W2109132899 cites W2005091462 @default.
• W2109132899 cites W2010469851 @default.
• W2109132899 cites W2011471302 @default.
• W2109132899 cites W2013978484 @default.
• W2109132899 cites W2037976962 @default.
• W2109132899 cites W2041056488 @default.
• W2109132899 cites W2044334793 @default.
• W2109132899 cites W2048341382 @default.
• W2109132899 cites W2056040568 @default.
• W2109132899 cites W2056209478 @default.
• W2109132899 cites W2059529519 @default.
• W2109132899 cites W2066246367 @default.
• W2109132899 cites W2068272711 @default.
• W2109132899 cites W2075327503 @default.
• W2109132899 cites W2082716921 @default.
• W2109132899 cites W2090489482 @default.
• W2109132899 cites W2096462010 @default.
• W2109132899 cites W2105794709 @default.
• W2109132899 cites W2106049726 @default.
• W2109132899 cites W2115068422 @default.
• W2109132899 cites W2115187741 @default.
• W2109132899 cites W2117086365 @default.
• W2109132899 cites W2152348310 @default.
• W2109132899 cites W2165945595 @default.
• W2109132899 cites W3176254103 @default.
• W2109132899 doi "https://doi.org/10.1093/rheumatology/38.11.1074" @default.
• W2109132899 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10556258" @default.
• W2109132899 hasPublicationYear "1999" @default.
• W2109132899 type Work @default.
• W2109132899 sameAs 2109132899 @default.
• W2109132899 citedByCount "137" @default.
• W2109132899 countsByYear W21091328992012 @default.
• W2109132899 countsByYear W21091328992013 @default.
• W2109132899 countsByYear W21091328992014 @default.
• W2109132899 countsByYear W21091328992015 @default.
• W2109132899 countsByYear W21091328992016 @default.
• W2109132899 countsByYear W21091328992017 @default.
• W2109132899 countsByYear W21091328992018 @default.
• W2109132899 countsByYear W21091328992019 @default.
• W2109132899 countsByYear W21091328992020 @default.
• W2109132899 countsByYear W21091328992021 @default.
• W2109132899 countsByYear W21091328992023 @default.
• W2109132899 crossrefType "journal-article" @default.
• W2109132899 hasAuthorship W2109132899A5001031394 @default.
• W2109132899 hasAuthorship W2109132899A5008292605 @default.
• W2109132899 hasAuthorship W2109132899A5012564728 @default.
• W2109132899 hasAuthorship W2109132899A5047229092 @default.
• W2109132899 hasAuthorship W2109132899A5052424289 @default.
• W2109132899 hasAuthorship W2109132899A5084807129 @default.
• W2109132899 hasBestOaLocation W21091328991 @default.
• W2109132899 hasConcept C10205521 @default.
• W2109132899 hasConcept C126322002 @default.
• W2109132899 hasConcept C142724271 @default.
• W2109132899 hasConcept C159912055 @default.
• W2109132899 hasConcept C204232928 @default.
• W2109132899 hasConcept C204787440 @default.
• W2109132899 hasConcept C2776164576 @default.
• W2109132899 hasConcept C2776260265 @default.
• W2109132899 hasConcept C2776460901 @default.
• W2109132899 hasConcept C2777077863 @default.
• W2109132899 hasConcept C2777402515 @default.
• W2109132899 hasConcept C2777575956 @default.
• W2109132899 hasConcept C2777652487 @default.
• W2109132899 hasConcept C28328180 @default.
• W2109132899 hasConcept C54355233 @default.
• W2109132899 hasConcept C71924100 @default.
• W2109132899 hasConcept C86803240 @default.
• W2109132899 hasConcept C90924648 @default.
• W2109132899 hasConceptScore W2109132899C10205521 @default.
• W2109132899 hasConceptScore W2109132899C126322002 @default.
• W2109132899 hasConceptScore W2109132899C142724271 @default.
• W2109132899 hasConceptScore W2109132899C159912055 @default.
• W2109132899 hasConceptScore W2109132899C204232928 @default.
• W2109132899 hasConceptScore W2109132899C204787440 @default.
• W2109132899 hasConceptScore W2109132899C2776164576 @default.
• W2109132899 hasConceptScore W2109132899C2776260265 @default.
• W2109132899 hasConceptScore W2109132899C2776460901 @default.
• W2109132899 hasConceptScore W2109132899C2777077863 @default.
• W2109132899 hasConceptScore W2109132899C2777402515 @default.
• W2109132899 hasConceptScore W2109132899C2777575956 @default.
• W2109132899 hasConceptScore W2109132899C2777652487 @default.

• next