FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2109134613> ?p ?o ?g. }

• W2109134613 endingPage "1778" @default.
• W2109134613 startingPage "1774" @default.
• W2109134613 abstract "ABSTRACT Access to sputum smear microscopy in high-tuberculosis (TB)-burden regions is limited by a scarcity of microscopes and experienced technicians. We evaluated the accuracy of CellScope, a novel digital fluorescence microscope that may expand access to microscopy. The study utilized smear microscopy slides prepared from sputum specimens submitted by consecutive adults with ≥2 weeks of cough who were admitted to Mulago Hospital (Kampala, Uganda). Conventional light-emitting diode (LED) fluorescence microscopy (FM) and mycobacterial culture were performed by experienced technicians. Two U.S.-based postgraduate researchers without prior microscopy experience restained, imaged, and interpreted the slides using CellScope. We assessed whether sensitivity and specificity of CellScope-based LED FM was noninferior to conventional LED FM by using a preselected margin of inferiority of 15%. Of 525 patients included, 72% were HIV seropositive and 39% had culture-confirmed TB. The proportions of positive results were similar with CellScope and conventional LED FM (34% versus 32%, respectively; P = 0.32), and agreement was substantial. CellScope accuracy was within the noninferiority margin for both sensitivity (63% versus 70%; difference, −7%; 95% confidence interval [CI], −13% to −1%) and specificity (85% versus 92%; difference, −7%; 95% CI, −12% to −3%). A subanalysis of 43 slides evaluated by each CellScope reader found substantial interreader reliability (custom-weighted kappa, 0.65) and variable intrareader reliability (custom-weighted kappa, 0.11 versus 0.48). CellScope offers promise for expanding microscopy services. Future studies should evaluate the device when operated by health workers in low-resource settings, the feasibility of image transmission and analysis by experienced microscopists, and the accuracy of automated image analysis algorithms." @default.
• W2109134613 created "2016-06-24" @default.
• W2109134613 creator A5004781847 @default.
• W2109134613 creator A5006645132 @default.
• W2109134613 creator A5012492855 @default.
• W2109134613 creator A5022196428 @default.
• W2109134613 creator A5035790758 @default.
• W2109134613 creator A5050263980 @default.
• W2109134613 creator A5073273696 @default.
• W2109134613 creator A5075140316 @default.
• W2109134613 creator A5079147838 @default.
• W2109134613 creator A5084102341 @default.
• W2109134613 date "2013-06-01" @default.
• W2109134613 modified "2023-10-15" @default.
• W2109134613 title "Mobile Digital Fluorescence Microscopy for Diagnosis of Tuberculosis" @default.
• W2109134613 cites W1517436550 @default.
• W2109134613 cites W1916400104 @default.
• W2109134613 cites W1988939739 @default.
• W2109134613 cites W1995225866 @default.
• W2109134613 cites W2031104662 @default.
• W2109134613 cites W2040822853 @default.
• W2109134613 cites W2055819954 @default.
• W2109134613 cites W2061005277 @default.
• W2109134613 cites W2061427434 @default.
• W2109134613 cites W2069781503 @default.
• W2109134613 cites W2074210909 @default.
• W2109134613 cites W2077374589 @default.
• W2109134613 cites W2079046645 @default.
• W2109134613 cites W2103468849 @default.
• W2109134613 cites W2104431608 @default.
• W2109134613 cites W2107446706 @default.
• W2109134613 cites W2139681679 @default.
• W2109134613 cites W2142416773 @default.
• W2109134613 cites W2142453887 @default.
• W2109134613 cites W2154326381 @default.
• W2109134613 cites W2158021940 @default.
• W2109134613 cites W2160020599 @default.
• W2109134613 cites W2161433272 @default.
• W2109134613 cites W2164777277 @default.
• W2109134613 cites W2164897446 @default.
• W2109134613 cites W4211162439 @default.
• W2109134613 doi "https://doi.org/10.1128/jcm.03432-12" @default.
• W2109134613 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3716054" @default.
• W2109134613 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23554191" @default.
• W2109134613 hasPublicationYear "2013" @default.
• W2109134613 type Work @default.
• W2109134613 sameAs 2109134613 @default.
• W2109134613 citedByCount "53" @default.
• W2109134613 countsByYear W21091346132014 @default.
• W2109134613 countsByYear W21091346132015 @default.
• W2109134613 countsByYear W21091346132016 @default.
• W2109134613 countsByYear W21091346132017 @default.
• W2109134613 countsByYear W21091346132018 @default.
• W2109134613 countsByYear W21091346132019 @default.
• W2109134613 countsByYear W21091346132020 @default.
• W2109134613 countsByYear W21091346132021 @default.
• W2109134613 countsByYear W21091346132023 @default.
• W2109134613 crossrefType "journal-article" @default.
• W2109134613 hasAuthorship W2109134613A5004781847 @default.
• W2109134613 hasAuthorship W2109134613A5006645132 @default.
• W2109134613 hasAuthorship W2109134613A5012492855 @default.
• W2109134613 hasAuthorship W2109134613A5022196428 @default.
• W2109134613 hasAuthorship W2109134613A5035790758 @default.
• W2109134613 hasAuthorship W2109134613A5050263980 @default.
• W2109134613 hasAuthorship W2109134613A5073273696 @default.
• W2109134613 hasAuthorship W2109134613A5075140316 @default.
• W2109134613 hasAuthorship W2109134613A5079147838 @default.
• W2109134613 hasAuthorship W2109134613A5084102341 @default.
• W2109134613 hasBestOaLocation W21091346131 @default.
• W2109134613 hasConcept C120665830 @default.
• W2109134613 hasConcept C121332964 @default.
• W2109134613 hasConcept C126322002 @default.
• W2109134613 hasConcept C142724271 @default.
• W2109134613 hasConcept C147080431 @default.
• W2109134613 hasConcept C169274487 @default.
• W2109134613 hasConcept C2776301714 @default.
• W2109134613 hasConcept C2781069245 @default.
• W2109134613 hasConcept C2989005 @default.
• W2109134613 hasConcept C44249647 @default.
• W2109134613 hasConcept C71924100 @default.
• W2109134613 hasConcept C91881484 @default.
• W2109134613 hasConceptScore W2109134613C120665830 @default.
• W2109134613 hasConceptScore W2109134613C121332964 @default.
• W2109134613 hasConceptScore W2109134613C126322002 @default.
• W2109134613 hasConceptScore W2109134613C142724271 @default.
• W2109134613 hasConceptScore W2109134613C147080431 @default.
• W2109134613 hasConceptScore W2109134613C169274487 @default.
• W2109134613 hasConceptScore W2109134613C2776301714 @default.
• W2109134613 hasConceptScore W2109134613C2781069245 @default.
• W2109134613 hasConceptScore W2109134613C2989005 @default.
• W2109134613 hasConceptScore W2109134613C44249647 @default.
• W2109134613 hasConceptScore W2109134613C71924100 @default.
• W2109134613 hasConceptScore W2109134613C91881484 @default.
• W2109134613 hasIssue "6" @default.
• W2109134613 hasLocation W21091346131 @default.
• W2109134613 hasLocation W21091346132 @default.
• W2109134613 hasLocation W21091346133 @default.
• W2109134613 hasLocation W21091346134 @default.

• next