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• W2109137798 startingPage "68" @default.
• W2109137798 abstract "The threshold for detecting amplitude modulation (AM) decreases with increasing duration of the AM sound up to several hundred milliseconds. If the auditory evoked steady-state response (SSR) to AM sound is an electrophysiological correlate of AM processing in the human brain, the development of the SSR should follow this course of temporal integration. Magnetoencephalographic recordings of SSR to 40 Hz AM tone-bursts were compared with responses to non-modulated tone-bursts at inter-stimulus intervals (ISIs) of 3, 1, and 0.5 s. Both types of stimuli elicited a transient gamma-band response (GBR), an N1 wave, and a sustained field (SF) during stimulus presentation. The AM stimulus evoked an additional 40 Hz SSR. The N1 amplitude was strongly reduced with shortened ISI, whereas the amplitudes of SSR, GBR, and SF were little affected by the ISI. Magnetic source-localization procedures estimated the generators of the early GBR, the SSR, and the SF to be anterior and medial to the sources of the N1. The sources of the SSR were in primary auditory cortex and separate from GBR sources. The SSR amplitude increased monotonically over a 200 ms period beginning about 40 ms after stimulus onset. The time course of the SSR phase reliably measured the duration of this transition to the steady state. At stimulus offset the SSR ceased within 50 ms. These results indicate that the primary auditory cortex responds immediately to stimulus changes and integrates stimulus features over a period of about 200 ms." @default.
• W2109137798 created "2016-06-24" @default.
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• W2109137798 date "2002-03-01" @default.
• W2109137798 modified "2023-10-09" @default.
• W2109137798 title "Temporal integration in the human auditory cortex as represented by the development of the steady-state magnetic field" @default.
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• W2109137798 doi "https://doi.org/10.1016/s0378-5955(02)00285-x" @default.
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