Matches in SemOpenAlex for { <https://semopenalex.org/work/W2109145840> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2109145840 endingPage "1363" @default.
- W2109145840 startingPage "1357" @default.
- W2109145840 abstract "Acetylcholinesterase (AChE) staining of rectal mucosal biopsy specimens is the most important and popular examination for making a definite diagnosis of Hirschsprung's disease. This examination often is performed for patients with constipation in the daily clinic. The results of this examination are reflected immediately in the treatment. However, the authors sometimes encountered difficult cases to diagnose, especially in neonates. Therefore, a retrospective investigation was conducted on the benefits and problems of AChE staining of rectal mucosal biopsy specimens in neonates.The authors encountered 459 cases (91 neonates) of suspected Hirschsprung's disease, clinically, from April 1986 to March 2000. Mucosal specimens were taken by punch biopsies. Samples were stained by the modified Karnovsky Roots method using rubeanic acid as an amplifier and immediately examined with a light microscope. These results were collected and assessed mainly on neonatal cases. The authors also analyzed the 104 cases of Hirschsprung's disease diagnosed in patients less than 1 year of age to evaluate the relationship between the grade of proliferation of AChE positive fiber and age.Forty-one neonatal cases of Hirschsprung's disease were diagnosed based on the findings of AChE staining. A definite diagnosis of Hirschsprung's disease was confirmed based on the pathologic findings of operative samples. Forty-eight cases that were diagnosed as normal included 4 cases that turned out to be false-negative (3 Hirschspurung's disease cases and 1 case of an allied disorder of Hirschsprung's disease). There were no major complications in mucosal punch biopsy. In the cases of Hirschsprung's disease diagnosed in a patient less than 1 year of age, the grade of AChE-positive fiber tended to increase with the aging of patients.The specificity of AChE staining was high (100%), but its sensitivity was slightly low (91%). Careful long-term follow-up is required for any cases diagnosed as normal. Mucosal biopsies should be repeated in cases of persistent clinical symptoms." @default.
- W2109145840 created "2016-06-24" @default.
- W2109145840 creator A5005189268 @default.
- W2109145840 creator A5043041975 @default.
- W2109145840 creator A5054715205 @default.
- W2109145840 creator A5055667470 @default.
- W2109145840 creator A5085555561 @default.
- W2109145840 date "2001-09-01" @default.
- W2109145840 modified "2023-10-02" @default.
- W2109145840 title "Fourteen-year experience of acetylcholinesterase staining for rectal mucosal biopsy in neonatal Hirschsprung's disease" @default.
- W2109145840 cites W1970574482 @default.
- W2109145840 cites W1992148499 @default.
- W2109145840 cites W1993703267 @default.
- W2109145840 cites W2008189088 @default.
- W2109145840 cites W2015692883 @default.
- W2109145840 cites W2034044130 @default.
- W2109145840 cites W2036101544 @default.
- W2109145840 cites W2039439919 @default.
- W2109145840 cites W2066358417 @default.
- W2109145840 cites W2077593786 @default.
- W2109145840 cites W2089710038 @default.
- W2109145840 cites W2119125561 @default.
- W2109145840 doi "https://doi.org/10.1053/jpsu.2001.26369" @default.
- W2109145840 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11528605" @default.
- W2109145840 hasPublicationYear "2001" @default.
- W2109145840 type Work @default.
- W2109145840 sameAs 2109145840 @default.
- W2109145840 citedByCount "52" @default.
- W2109145840 countsByYear W21091458402012 @default.
- W2109145840 countsByYear W21091458402013 @default.
- W2109145840 countsByYear W21091458402014 @default.
- W2109145840 countsByYear W21091458402015 @default.
- W2109145840 countsByYear W21091458402016 @default.
- W2109145840 countsByYear W21091458402017 @default.
- W2109145840 countsByYear W21091458402018 @default.
- W2109145840 countsByYear W21091458402019 @default.
- W2109145840 countsByYear W21091458402020 @default.
- W2109145840 countsByYear W21091458402021 @default.
- W2109145840 countsByYear W21091458402022 @default.
- W2109145840 crossrefType "journal-article" @default.
- W2109145840 hasAuthorship W2109145840A5005189268 @default.
- W2109145840 hasAuthorship W2109145840A5043041975 @default.
- W2109145840 hasAuthorship W2109145840A5054715205 @default.
- W2109145840 hasAuthorship W2109145840A5055667470 @default.
- W2109145840 hasAuthorship W2109145840A5085555561 @default.
- W2109145840 hasConcept C141071460 @default.
- W2109145840 hasConcept C142724271 @default.
- W2109145840 hasConcept C2775934546 @default.
- W2109145840 hasConcept C2779089422 @default.
- W2109145840 hasConcept C2779134260 @default.
- W2109145840 hasConcept C2779222388 @default.
- W2109145840 hasConcept C2781112942 @default.
- W2109145840 hasConcept C71924100 @default.
- W2109145840 hasConcept C74864618 @default.
- W2109145840 hasConcept C90924648 @default.
- W2109145840 hasConceptScore W2109145840C141071460 @default.
- W2109145840 hasConceptScore W2109145840C142724271 @default.
- W2109145840 hasConceptScore W2109145840C2775934546 @default.
- W2109145840 hasConceptScore W2109145840C2779089422 @default.
- W2109145840 hasConceptScore W2109145840C2779134260 @default.
- W2109145840 hasConceptScore W2109145840C2779222388 @default.
- W2109145840 hasConceptScore W2109145840C2781112942 @default.
- W2109145840 hasConceptScore W2109145840C71924100 @default.
- W2109145840 hasConceptScore W2109145840C74864618 @default.
- W2109145840 hasConceptScore W2109145840C90924648 @default.
- W2109145840 hasFunder F4320321408 @default.
- W2109145840 hasIssue "9" @default.
- W2109145840 hasLocation W21091458401 @default.
- W2109145840 hasLocation W21091458402 @default.
- W2109145840 hasOpenAccess W2109145840 @default.
- W2109145840 hasPrimaryLocation W21091458401 @default.
- W2109145840 hasRelatedWork W149619926 @default.
- W2109145840 hasRelatedWork W2007932553 @default.
- W2109145840 hasRelatedWork W2090001869 @default.
- W2109145840 hasRelatedWork W2396171954 @default.
- W2109145840 hasRelatedWork W2410032340 @default.
- W2109145840 hasRelatedWork W245252065 @default.
- W2109145840 hasRelatedWork W2563854593 @default.
- W2109145840 hasRelatedWork W2753057714 @default.
- W2109145840 hasRelatedWork W30104120 @default.
- W2109145840 hasRelatedWork W3153192368 @default.
- W2109145840 hasVolume "36" @default.
- W2109145840 isParatext "false" @default.
- W2109145840 isRetracted "false" @default.
- W2109145840 magId "2109145840" @default.
- W2109145840 workType "article" @default.