Matches in SemOpenAlex for { <https://semopenalex.org/work/W2109179624> ?p ?o ?g. }
- W2109179624 endingPage "2252" @default.
- W2109179624 startingPage "2241" @default.
- W2109179624 abstract "Persistent oxidative stress is one of the major causes of most lifestyle-related diseases, cancer and the aging process. Acute oxidative stress directly causes serious damage to tissues. Despite the clinical importance of oxidative damage, antioxidants have been of limited therapeutic success. We have proposed that molecular hydrogen (H2) has potential as a “novel” antioxidant in preventive and therapeutic applications [Ohsawa et al., Nat Med. 2007: 13; 688-94]. H2 has a number of advantages as a potential antioxidant: H2 rapidly diffuses into tissues and cells, and it is mild enough neither to disturb metabolic redox reactions nor to affect reactive oxygen species (ROS) that function in cell signaling, thereby, there should be little adverse effects of consuming H2. There are several methods to ingest or consume H2, including inhaling hydrogen gas, drinking H2-dissolved water (hydrogen water), taking a hydrogen bath, injecting H2- dissolved saline (hydrogen saline), dropping hydrogen saline onto the eye, and increasing the production of intestinal H2 by bacteria. Since the publication of the first H2 paper in Nature Medicine in 2007, the biological effects of H2 have been confirmed by the publication of more than 38 diseases, physiological states and clinical tests in leading biological/medical journals, and several groups have started clinical examinations. Moreover, H2 shows not only effects against oxidative stress, but also various anti-inflammatory and antiallergic effects. H2 regulates various gene expressions and protein-phosphorylations, though the molecular mechanisms underlying the marked effects of very small amounts of H2 remain elusive." @default.
- W2109179624 created "2016-06-24" @default.
- W2109179624 creator A5044949829 @default.
- W2109179624 date "2011-07-01" @default.
- W2109179624 modified "2023-09-26" @default.
- W2109179624 title "Recent Progress Toward Hydrogen Medicine: Potential of Molecular Hydrogen for Preventive and Therapeutic Applications" @default.
- W2109179624 cites W1501371332 @default.
- W2109179624 cites W1546743948 @default.
- W2109179624 cites W1630602822 @default.
- W2109179624 cites W163238371 @default.
- W2109179624 cites W17013332 @default.
- W2109179624 cites W1922087192 @default.
- W2109179624 cites W1960027359 @default.
- W2109179624 cites W1963789809 @default.
- W2109179624 cites W1965136528 @default.
- W2109179624 cites W1966753962 @default.
- W2109179624 cites W1973233271 @default.
- W2109179624 cites W1973536579 @default.
- W2109179624 cites W1976616659 @default.
- W2109179624 cites W1981538366 @default.
- W2109179624 cites W1985525173 @default.
- W2109179624 cites W1990296073 @default.
- W2109179624 cites W1990465549 @default.
- W2109179624 cites W1990829099 @default.
- W2109179624 cites W1991728780 @default.
- W2109179624 cites W1992049458 @default.
- W2109179624 cites W1993250284 @default.
- W2109179624 cites W1994509157 @default.
- W2109179624 cites W1998199040 @default.
- W2109179624 cites W2002727344 @default.
- W2109179624 cites W2002741688 @default.
- W2109179624 cites W2002769318 @default.
- W2109179624 cites W2003104658 @default.
- W2109179624 cites W2004129180 @default.
- W2109179624 cites W2004692084 @default.
- W2109179624 cites W2005299241 @default.
- W2109179624 cites W2006210634 @default.
- W2109179624 cites W2010714560 @default.
- W2109179624 cites W2011031473 @default.
- W2109179624 cites W2013968205 @default.
- W2109179624 cites W2013970530 @default.
- W2109179624 cites W2015032101 @default.
- W2109179624 cites W2015356704 @default.
- W2109179624 cites W2017288304 @default.
- W2109179624 cites W2020417577 @default.
- W2109179624 cites W2027375453 @default.
- W2109179624 cites W2028606217 @default.
- W2109179624 cites W2029749250 @default.
- W2109179624 cites W2033078592 @default.
- W2109179624 cites W2035999441 @default.
- W2109179624 cites W2038926224 @default.
- W2109179624 cites W2042614482 @default.
- W2109179624 cites W2045018966 @default.
- W2109179624 cites W2048547503 @default.
- W2109179624 cites W2049800847 @default.
- W2109179624 cites W2049842515 @default.
- W2109179624 cites W2050897300 @default.
- W2109179624 cites W2051243229 @default.
- W2109179624 cites W2054526264 @default.
- W2109179624 cites W2059982861 @default.
- W2109179624 cites W2065076024 @default.
- W2109179624 cites W2065663588 @default.
- W2109179624 cites W2066344747 @default.
- W2109179624 cites W2066531899 @default.
- W2109179624 cites W2067683280 @default.
- W2109179624 cites W2067757114 @default.
- W2109179624 cites W2079380240 @default.
- W2109179624 cites W2083342497 @default.
- W2109179624 cites W2083668480 @default.
- W2109179624 cites W2086810938 @default.
- W2109179624 cites W2087365545 @default.
- W2109179624 cites W2091214272 @default.
- W2109179624 cites W2091261755 @default.
- W2109179624 cites W2093055423 @default.
- W2109179624 cites W2093838944 @default.
- W2109179624 cites W2094156327 @default.
- W2109179624 cites W2097155911 @default.
- W2109179624 cites W2098311641 @default.
- W2109179624 cites W2098689751 @default.
- W2109179624 cites W2098970247 @default.
- W2109179624 cites W2101861123 @default.
- W2109179624 cites W2104720406 @default.
- W2109179624 cites W2104989412 @default.
- W2109179624 cites W2105086774 @default.
- W2109179624 cites W2105296043 @default.
- W2109179624 cites W2105731956 @default.
- W2109179624 cites W2105754268 @default.
- W2109179624 cites W2108319424 @default.
- W2109179624 cites W2109257509 @default.
- W2109179624 cites W2110155106 @default.
- W2109179624 cites W2111068054 @default.
- W2109179624 cites W2112951169 @default.
- W2109179624 cites W2113782791 @default.
- W2109179624 cites W2115038361 @default.
- W2109179624 cites W2115915717 @default.
- W2109179624 cites W2116454569 @default.
- W2109179624 cites W2117252625 @default.
- W2109179624 cites W2117396891 @default.