Matches in SemOpenAlex for { <https://semopenalex.org/work/W2109184910> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W2109184910 endingPage "546" @default.
- W2109184910 startingPage "542" @default.
- W2109184910 abstract "Aims: The diagnosis of renal oncocytomas (ROs) and chromophobe renal cell carcinomas (RCCs) based on histological features is often uncertain. To assess the value of genetic analysis in their differential diagnosis we analysed 27 ROs and 21 chromophobe RCCs by microsatellite allelotyping. Methods and results: Markers at the short and long arms of chromosomes specifically involved in the genetic changes of the four main types of renal cancers were selected. Allelic changes were identified by automated sequencing. Allelic changes at chromosome 1p occurred in 8/26 (31%) and at chromosome 14q in 4/27 (15%) ROs. Loss of heterozygosity (LOH) at chromosomes 1, 2, 6, 10, 13, 17 and 21 were seen in 90%, 90%, 96%, 86%, 85%, 90% and 72% of the chromophobe RCCs, respectively. Alterations of at least three of these chromosomal sites were detected in each chromophobe RCC. In addition, we found recurrent LOH at chromosomes 9p23 (43%), 18q22 (30%), 5q22 (28%) and 8p (28%) in chromophobe RCCs. Conclusions: Chromophobe RCCs can be differentiated from ROs by analysing specific chromosomal regions with microsatellites." @default.
- W2109184910 created "2016-06-24" @default.
- W2109184910 creator A5023486650 @default.
- W2109184910 creator A5054167869 @default.
- W2109184910 creator A5065717057 @default.
- W2109184910 date "2004-06-01" @default.
- W2109184910 modified "2023-10-16" @default.
- W2109184910 title "Microsatellite allelotyping differentiates chromophobe renal cell carcinomas from renal oncocytomas and identifies new genetic changes" @default.
- W2109184910 cites W1969841042 @default.
- W2109184910 cites W1979566578 @default.
- W2109184910 cites W1992319677 @default.
- W2109184910 cites W2007654659 @default.
- W2109184910 cites W2016384431 @default.
- W2109184910 cites W2017412286 @default.
- W2109184910 cites W2023593683 @default.
- W2109184910 cites W2030086616 @default.
- W2109184910 cites W2036691029 @default.
- W2109184910 cites W2100364065 @default.
- W2109184910 cites W2112775523 @default.
- W2109184910 cites W2122909535 @default.
- W2109184910 cites W2141805646 @default.
- W2109184910 cites W2154161331 @default.
- W2109184910 cites W27419332 @default.
- W2109184910 cites W34599157 @default.
- W2109184910 doi "https://doi.org/10.1111/j.1365-2559.2004.01884.x" @default.
- W2109184910 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15186268" @default.
- W2109184910 hasPublicationYear "2004" @default.
- W2109184910 type Work @default.
- W2109184910 sameAs 2109184910 @default.
- W2109184910 citedByCount "38" @default.
- W2109184910 countsByYear W21091849102012 @default.
- W2109184910 countsByYear W21091849102014 @default.
- W2109184910 countsByYear W21091849102015 @default.
- W2109184910 countsByYear W21091849102017 @default.
- W2109184910 countsByYear W21091849102018 @default.
- W2109184910 countsByYear W21091849102020 @default.
- W2109184910 countsByYear W21091849102022 @default.
- W2109184910 crossrefType "journal-article" @default.
- W2109184910 hasAuthorship W2109184910A5023486650 @default.
- W2109184910 hasAuthorship W2109184910A5054167869 @default.
- W2109184910 hasAuthorship W2109184910A5065717057 @default.
- W2109184910 hasConcept C104317684 @default.
- W2109184910 hasConcept C142724271 @default.
- W2109184910 hasConcept C143589142 @default.
- W2109184910 hasConcept C180754005 @default.
- W2109184910 hasConcept C2777472916 @default.
- W2109184910 hasConcept C2778560582 @default.
- W2109184910 hasConcept C2780091579 @default.
- W2109184910 hasConcept C2780674462 @default.
- W2109184910 hasConcept C54355233 @default.
- W2109184910 hasConcept C71924100 @default.
- W2109184910 hasConcept C78795084 @default.
- W2109184910 hasConcept C86803240 @default.
- W2109184910 hasConceptScore W2109184910C104317684 @default.
- W2109184910 hasConceptScore W2109184910C142724271 @default.
- W2109184910 hasConceptScore W2109184910C143589142 @default.
- W2109184910 hasConceptScore W2109184910C180754005 @default.
- W2109184910 hasConceptScore W2109184910C2777472916 @default.
- W2109184910 hasConceptScore W2109184910C2778560582 @default.
- W2109184910 hasConceptScore W2109184910C2780091579 @default.
- W2109184910 hasConceptScore W2109184910C2780674462 @default.
- W2109184910 hasConceptScore W2109184910C54355233 @default.
- W2109184910 hasConceptScore W2109184910C71924100 @default.
- W2109184910 hasConceptScore W2109184910C78795084 @default.
- W2109184910 hasConceptScore W2109184910C86803240 @default.
- W2109184910 hasIssue "6" @default.
- W2109184910 hasLocation W21091849101 @default.
- W2109184910 hasLocation W21091849102 @default.
- W2109184910 hasOpenAccess W2109184910 @default.
- W2109184910 hasPrimaryLocation W21091849101 @default.
- W2109184910 hasRelatedWork W1148744626 @default.
- W2109184910 hasRelatedWork W1987324944 @default.
- W2109184910 hasRelatedWork W1993757548 @default.
- W2109184910 hasRelatedWork W2005415204 @default.
- W2109184910 hasRelatedWork W2065414041 @default.
- W2109184910 hasRelatedWork W2146606485 @default.
- W2109184910 hasRelatedWork W2147264650 @default.
- W2109184910 hasRelatedWork W2583004967 @default.
- W2109184910 hasRelatedWork W2606487677 @default.
- W2109184910 hasRelatedWork W2889181124 @default.
- W2109184910 hasVolume "44" @default.
- W2109184910 isParatext "false" @default.
- W2109184910 isRetracted "false" @default.
- W2109184910 magId "2109184910" @default.
- W2109184910 workType "article" @default.