Matches in SemOpenAlex for { <https://semopenalex.org/work/W2109201316> ?p ?o ?g. }
- W2109201316 endingPage "572" @default.
- W2109201316 startingPage "568" @default.
- W2109201316 abstract "The recently discovered apolipoprotein A5 ( APOA5 ) gene has been shown to be important in determining plasma triglyceride levels, a major cardiovascular disease risk factor. We searched for possible associations of the APOA5 gene polymorphisms S19W and -1131T>C with coronary heart disease (CHD) in a Chinese population. A total of 483 Chinese CHD patients and 502 control non-CHD subjects were genotyped by polymerase chain reaction-restriction fragment length polymorphism for these 2 single nucleotide polymorphisms. We found that the minor allele 19W was observed only in CHD patients and not in controls, with allelic frequencies of 0.047 and 0.000, respectively ( P < .000001), and the minor allele -1131C was significantly higher in CHD patients than in controls (0.391 vs 0.299, P < .0001). These results suggest that both the S19W and -1131T>C variations in the APOA5 gene are associated with the CHD and appear to be 2 genetic risk factors for CHD susceptibility in Chinese. Moreover, we found that triglyceride levels were significantly higher in -1131C carriers than in -1131T subjects of the control group and that high-density-lipoprotein cholesterol was decreased in -1131C carriers among CHD patients." @default.
- W2109201316 created "2016-06-24" @default.
- W2109201316 creator A5000666349 @default.
- W2109201316 creator A5007404893 @default.
- W2109201316 creator A5009264615 @default.
- W2109201316 creator A5021941803 @default.
- W2109201316 creator A5028243061 @default.
- W2109201316 creator A5029237881 @default.
- W2109201316 creator A5030327843 @default.
- W2109201316 creator A5037957877 @default.
- W2109201316 creator A5038460341 @default.
- W2109201316 creator A5047899644 @default.
- W2109201316 creator A5058016106 @default.
- W2109201316 creator A5058202082 @default.
- W2109201316 creator A5062591755 @default.
- W2109201316 creator A5074019867 @default.
- W2109201316 creator A5084677120 @default.
- W2109201316 date "2005-05-01" @default.
- W2109201316 modified "2023-10-01" @default.
- W2109201316 title "Association between DNA variant sites in the apolipoprotein A5 gene and coronary heart disease in Chinese" @default.
- W2109201316 cites W1909965669 @default.
- W2109201316 cites W1995897030 @default.
- W2109201316 cites W2015692830 @default.
- W2109201316 cites W2023466812 @default.
- W2109201316 cites W2032849264 @default.
- W2109201316 cites W2047138666 @default.
- W2109201316 cites W2059803032 @default.
- W2109201316 cites W2079460525 @default.
- W2109201316 cites W2102100819 @default.
- W2109201316 cites W2109811986 @default.
- W2109201316 cites W2113481191 @default.
- W2109201316 cites W2118094114 @default.
- W2109201316 cites W2129741326 @default.
- W2109201316 cites W2132198142 @default.
- W2109201316 cites W2133025759 @default.
- W2109201316 cites W2133140402 @default.
- W2109201316 cites W2134466257 @default.
- W2109201316 cites W2135472469 @default.
- W2109201316 cites W2141163113 @default.
- W2109201316 cites W2162588312 @default.
- W2109201316 cites W2164809128 @default.
- W2109201316 cites W2171101992 @default.
- W2109201316 cites W4232807629 @default.
- W2109201316 doi "https://doi.org/10.1016/j.metabol.2004.11.009" @default.
- W2109201316 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15877284" @default.
- W2109201316 hasPublicationYear "2005" @default.
- W2109201316 type Work @default.
- W2109201316 sameAs 2109201316 @default.
- W2109201316 citedByCount "55" @default.
- W2109201316 countsByYear W21092013162012 @default.
- W2109201316 countsByYear W21092013162013 @default.
- W2109201316 countsByYear W21092013162014 @default.
- W2109201316 countsByYear W21092013162015 @default.
- W2109201316 countsByYear W21092013162016 @default.
- W2109201316 countsByYear W21092013162017 @default.
- W2109201316 countsByYear W21092013162018 @default.
- W2109201316 countsByYear W21092013162020 @default.
- W2109201316 countsByYear W21092013162023 @default.
- W2109201316 crossrefType "journal-article" @default.
- W2109201316 hasAuthorship W2109201316A5000666349 @default.
- W2109201316 hasAuthorship W2109201316A5007404893 @default.
- W2109201316 hasAuthorship W2109201316A5009264615 @default.
- W2109201316 hasAuthorship W2109201316A5021941803 @default.
- W2109201316 hasAuthorship W2109201316A5028243061 @default.
- W2109201316 hasAuthorship W2109201316A5029237881 @default.
- W2109201316 hasAuthorship W2109201316A5030327843 @default.
- W2109201316 hasAuthorship W2109201316A5037957877 @default.
- W2109201316 hasAuthorship W2109201316A5038460341 @default.
- W2109201316 hasAuthorship W2109201316A5047899644 @default.
- W2109201316 hasAuthorship W2109201316A5058016106 @default.
- W2109201316 hasAuthorship W2109201316A5058202082 @default.
- W2109201316 hasAuthorship W2109201316A5062591755 @default.
- W2109201316 hasAuthorship W2109201316A5074019867 @default.
- W2109201316 hasAuthorship W2109201316A5084677120 @default.
- W2109201316 hasConcept C104317684 @default.
- W2109201316 hasConcept C126322002 @default.
- W2109201316 hasConcept C134018914 @default.
- W2109201316 hasConcept C135763542 @default.
- W2109201316 hasConcept C153209595 @default.
- W2109201316 hasConcept C157410074 @default.
- W2109201316 hasConcept C180754005 @default.
- W2109201316 hasConcept C2778163477 @default.
- W2109201316 hasConcept C2778913445 @default.
- W2109201316 hasConcept C2779134260 @default.
- W2109201316 hasConcept C37463918 @default.
- W2109201316 hasConcept C54355233 @default.
- W2109201316 hasConcept C57089818 @default.
- W2109201316 hasConcept C62746215 @default.
- W2109201316 hasConcept C71924100 @default.
- W2109201316 hasConcept C86803240 @default.
- W2109201316 hasConceptScore W2109201316C104317684 @default.
- W2109201316 hasConceptScore W2109201316C126322002 @default.
- W2109201316 hasConceptScore W2109201316C134018914 @default.
- W2109201316 hasConceptScore W2109201316C135763542 @default.
- W2109201316 hasConceptScore W2109201316C153209595 @default.
- W2109201316 hasConceptScore W2109201316C157410074 @default.
- W2109201316 hasConceptScore W2109201316C180754005 @default.
- W2109201316 hasConceptScore W2109201316C2778163477 @default.