FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2109202458> ?p ?o ?g. }

• W2109202458 endingPage "186" @default.
• W2109202458 startingPage "176" @default.
• W2109202458 abstract "Only a subset of Shiga toxin (Stx)-producing Escherichia coli (STEC) are human pathogens, but the characteristics that account for differences in pathogenicity are not well understood. In this study, we investigated the distribution of the stx variants coding for Stx2 and its variants in highly virulent STEC of seropathotype A and low-pathogenic STEC of seropathotype C. We analysed and compared transcription of the corresponding genes, production of Shiga toxins, and stx-phage release in basal as well as in induced conditions. We found that the stx(2) variant was mainly associated with strains of seropathotype A, whereas most of the strains of seropathotype C possessed the stx(2-vhb) variant, which was frequently associated with stx(2), stx(2-vha) or stx(2c). Levels of stx(2) and stx(2)-related mRNA were higher in strains belonging to seropathotype A and in those strains of seropathotype C that express the stx(2) variant than in the remaining strains of seropathotype C. The stx(2-vhb) genes were the least expressed, in basal as well as in induced conditions, and in many cases did not seem to be carried by an inducible prophage. A clear correlation was observed between stx mRNA levels and stx-phage DNA in the culture supernatants, suggesting that most stx(2)-related genes are expressed only when they are carried by a phage. In conclusion, some relationship between stx(2)-related gene expression in vitro and the seropathotype of the STEC strains was observed. A higher expression of the stx(2) gene and a higher release of its product, in basal as well as in induced conditions, was observed in pathogenic strains of seropathotype A. A subset of strains of seropathotype C shows the same characteristics and could be a high risk to human health." @default.
• W2109202458 created "2016-06-24" @default.
• W2109202458 creator A5015680710 @default.
• W2109202458 creator A5021204021 @default.
• W2109202458 creator A5027681269 @default.
• W2109202458 creator A5053697493 @default.
• W2109202458 creator A5063979167 @default.
• W2109202458 creator A5073136107 @default.
• W2109202458 creator A5077983240 @default.
• W2109202458 date "2008-01-01" @default.
• W2109202458 modified "2023-10-02" @default.
• W2109202458 title "Differential expression of stx2 variants in Shiga toxin-producing Escherichia coli belonging to seropathotypes A and C" @default.
• W2109202458 cites W1498866358 @default.
• W2109202458 cites W1515704896 @default.
• W2109202458 cites W1885356084 @default.
• W2109202458 cites W1900792583 @default.
• W2109202458 cites W1920500439 @default.
• W2109202458 cites W1966197315 @default.
• W2109202458 cites W2003580215 @default.
• W2109202458 cites W2003915689 @default.
• W2109202458 cites W2008573474 @default.
• W2109202458 cites W2025507930 @default.
• W2109202458 cites W2042482682 @default.
• W2109202458 cites W2045864547 @default.
• W2109202458 cites W2063629053 @default.
• W2109202458 cites W2070810653 @default.
• W2109202458 cites W2077672202 @default.
• W2109202458 cites W2096176336 @default.
• W2109202458 cites W2102411651 @default.
• W2109202458 cites W2103798600 @default.
• W2109202458 cites W2110285283 @default.
• W2109202458 cites W2110704759 @default.
• W2109202458 cites W2112111992 @default.
• W2109202458 cites W2112705397 @default.
• W2109202458 cites W2117192186 @default.
• W2109202458 cites W2118152759 @default.
• W2109202458 cites W2123629406 @default.
• W2109202458 cites W2123932416 @default.
• W2109202458 cites W2123992498 @default.
• W2109202458 cites W2123994723 @default.
• W2109202458 cites W2129000564 @default.
• W2109202458 cites W2129623039 @default.
• W2109202458 cites W2130480234 @default.
• W2109202458 cites W2131159435 @default.
• W2109202458 cites W2137994690 @default.
• W2109202458 cites W2139133542 @default.
• W2109202458 cites W2139912385 @default.
• W2109202458 cites W2148775773 @default.
• W2109202458 cites W2150625556 @default.
• W2109202458 cites W2152964535 @default.
• W2109202458 cites W2154870173 @default.
• W2109202458 cites W2158277438 @default.
• W2109202458 cites W2164835198 @default.
• W2109202458 cites W2165157887 @default.
• W2109202458 cites W2165883557 @default.
• W2109202458 cites W2170846767 @default.
• W2109202458 cites W2171183281 @default.
• W2109202458 doi "https://doi.org/10.1099/mic.0.2007/009704-0" @default.
• W2109202458 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18174136" @default.
• W2109202458 hasPublicationYear "2008" @default.
• W2109202458 type Work @default.
• W2109202458 sameAs 2109202458 @default.
• W2109202458 citedByCount "74" @default.
• W2109202458 countsByYear W21092024582012 @default.
• W2109202458 countsByYear W21092024582013 @default.
• W2109202458 countsByYear W21092024582014 @default.
• W2109202458 countsByYear W21092024582015 @default.
• W2109202458 countsByYear W21092024582016 @default.
• W2109202458 countsByYear W21092024582017 @default.
• W2109202458 countsByYear W21092024582018 @default.
• W2109202458 countsByYear W21092024582019 @default.
• W2109202458 countsByYear W21092024582020 @default.
• W2109202458 countsByYear W21092024582021 @default.
• W2109202458 countsByYear W21092024582022 @default.
• W2109202458 countsByYear W21092024582023 @default.
• W2109202458 crossrefType "journal-article" @default.
• W2109202458 hasAuthorship W2109202458A5015680710 @default.
• W2109202458 hasAuthorship W2109202458A5021204021 @default.
• W2109202458 hasAuthorship W2109202458A5027681269 @default.
• W2109202458 hasAuthorship W2109202458A5053697493 @default.
• W2109202458 hasAuthorship W2109202458A5063979167 @default.
• W2109202458 hasAuthorship W2109202458A5073136107 @default.
• W2109202458 hasAuthorship W2109202458A5077983240 @default.
• W2109202458 hasBestOaLocation W21092024581 @default.
• W2109202458 hasConcept C104317684 @default.
• W2109202458 hasConcept C2775925610 @default.
• W2109202458 hasConcept C2776441376 @default.
• W2109202458 hasConcept C2777367657 @default.
• W2109202458 hasConcept C2778411228 @default.
• W2109202458 hasConcept C2781001907 @default.
• W2109202458 hasConcept C54355233 @default.
• W2109202458 hasConcept C547475151 @default.
• W2109202458 hasConcept C60987743 @default.
• W2109202458 hasConcept C73445445 @default.
• W2109202458 hasConcept C86803240 @default.
• W2109202458 hasConcept C89423630 @default.
• W2109202458 hasConceptScore W2109202458C104317684 @default.
• W2109202458 hasConceptScore W2109202458C2775925610 @default.

• next