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• W2109220021 endingPage "685" @default.
• W2109220021 startingPage "675" @default.
• W2109220021 abstract "The superfused retinal slice preparation was used to examine the morphology and glutamate-activated whole-cell currents of rabbit bipolar cells. There were six morphologically distinct types of cone bipolar cells and a rod bipolar cell that had axon terminals stratifying in stratum 3 to 5 of sublamina-b. All of these bipolar cell types exhibited an outward current in response to the application of the metabotropic glutamate receptor, mGluR6, agonist AP-4 (APB), and had I/V curves indicative of membrane channel closure. Conversely, there were no currents activated during the application of kainate, the AMPA/kainate receptor agonist. These data demonstrate they were on-bipolar cells. In addition, there were six morphologically distinct cone bipolar cells that stratified in sublamina-a. Every cell with axonal arborizations in stratum 1 and 2 exhibited an inward current when the ionotropic glutamate receptor agonist kainate was applied. This current was blocked by application of the AMPA/kainate receptor antagonist CNQX. These cells also decreased their membrane resistance in response to kainate, a characteristic of the opening of channels within the plasma membrane. Without exception, no cells stratifying in sublamina-a responded to the mGluR6 agonist AP-4, further identifying them as off-bipolar cells." @default.
• W2109220021 created "2016-06-24" @default.
• W2109220021 creator A5012032028 @default.
• W2109220021 creator A5081367274 @default.
• W2109220021 date "2001-09-01" @default.
• W2109220021 modified "2023-10-07" @default.
• W2109220021 title "Rabbit cone bipolar cells: Correlation of their morphologies with whole-cell recordings" @default.
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• W2109220021 doi "https://doi.org/10.1017/s0952523801185019" @default.
• W2109220021 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11925003" @default.
• W2109220021 hasPublicationYear "2001" @default.
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