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- W2109230829 abstract "Summary Background: Photopheresis (ECP) with the UVAR ® XTS™ system has been limited to patients with a body weight > 40 kg, because extracorporeal blood volumes (ECV) may exceed 15% of the total blood volumes in low‐body‐weight patients. Because of these instrument characteristics, the use of ECP is limited in pediatric patients. Patients and methods: In 5 patients (age 4 to 15 years) with graft‐versus‐host disease and with a body weight between 13 and 34 kilograms, photopheresis was performed using the UVAR ® XTS™ system. In 3 patients ECP could be performed by balancing the ECV with saline infusions. In 2 patients the system was modified in that the instrument was primed with packed red cells. During the treatment, fluid balance was guaranteed by a reservoir from a transfusion bag connected in parallel. Results: Together 223 procedures were performed, among them 28 with the modification of the system. The treatments were well tolerated, and no episodes of hypotension were observed. Conclusions: It is possible to run ECP in low‐body weight patients with the UVAR ® XTS™ system." @default.
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- W2109230829 date "2009-12-23" @default.
- W2109230829 modified "2023-10-17" @default.
- W2109230829 title "Photopheresis in pediatric patients with low-body weight using the UVAR®XTS™ system" @default.
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- W2109230829 doi "https://doi.org/10.1111/j.1610-0387.2009.07212.x" @default.
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