Matches in SemOpenAlex for { <https://semopenalex.org/work/W2109244975> ?p ?o ?g. }
- W2109244975 endingPage "568" @default.
- W2109244975 startingPage "560" @default.
- W2109244975 abstract "Abstract: The labeling pattern of the major individual gangliosides from the microsomal and synaptosomal fractions of rat brain was determined following intracerebral injection of the radioactive sialic acid precursor, N-acetylmannosamine. Microsomal gangliosides initially had a higher specific radioactivity than synaptosomal gangliosides, with both fractions reaching similar specific radioactivities 18 h after precursor injection. In both subcellular fractions, the polysialogangliosides GT1b and GQ1b were initially more highly labeled than all other gangliosides. With the establishment of the labeling pattern, the effect of the convulsant pentylenetetrazol on brain gangliosides was examined in detail. Significant decreases in radioactive label were noted in the polysialogangliosides, GT1b and GQ1b, from the synaptosomal and microsomal fractions of the convulsed animals. The decreases may be due to activation of the membrane-bound neuraminidase present with the gangliosides in neuronal tissue. Prior to experimentation, a methodology was developed to insure quantitative isolation of small amounts of ganglioside free of other lipids and water-soluble contaminants. Combination of this isolation procedure with quantitative densitometry of thin-layer chromatograms permits accurate distributional analyses for individual gangliosides. In applications involving radioactive gangliosides, the method allows the determination of both radioactivity and sialic acid distributions from the same thin-layer chromatogram." @default.
- W2109244975 created "2016-06-24" @default.
- W2109244975 creator A5015782749 @default.
- W2109244975 creator A5015833771 @default.
- W2109244975 creator A5046924659 @default.
- W2109244975 creator A5051306819 @default.
- W2109244975 creator A5068357617 @default.
- W2109244975 date "1980-03-01" @default.
- W2109244975 modified "2023-09-30" @default.
- W2109244975 title "Incorporation of N-Acetylmannosamine into Rat Brain Subcellular Gangliosides: Effect of Pentylenetetrazol-Induced Convulsions on Brain Gangliosides" @default.
- W2109244975 cites W1483908324 @default.
- W2109244975 cites W1504930799 @default.
- W2109244975 cites W1536299500 @default.
- W2109244975 cites W1589863512 @default.
- W2109244975 cites W1775749144 @default.
- W2109244975 cites W19750459 @default.
- W2109244975 cites W1976760410 @default.
- W2109244975 cites W1984532125 @default.
- W2109244975 cites W1986830225 @default.
- W2109244975 cites W1990431630 @default.
- W2109244975 cites W1995745826 @default.
- W2109244975 cites W2001398428 @default.
- W2109244975 cites W2012826989 @default.
- W2109244975 cites W2052314203 @default.
- W2109244975 cites W2058988473 @default.
- W2109244975 cites W2062223162 @default.
- W2109244975 cites W2068878336 @default.
- W2109244975 cites W2069103255 @default.
- W2109244975 cites W2073204868 @default.
- W2109244975 cites W2074295208 @default.
- W2109244975 cites W2075836148 @default.
- W2109244975 cites W2079452818 @default.
- W2109244975 cites W2081579279 @default.
- W2109244975 cites W2085459182 @default.
- W2109244975 cites W2086598635 @default.
- W2109244975 cites W2119378740 @default.
- W2109244975 cites W2168880443 @default.
- W2109244975 cites W217538494 @default.
- W2109244975 cites W2188869740 @default.
- W2109244975 cites W2218717935 @default.
- W2109244975 cites W2227508938 @default.
- W2109244975 cites W2399419977 @default.
- W2109244975 cites W2415583550 @default.
- W2109244975 cites W4211095852 @default.
- W2109244975 cites W4245195685 @default.
- W2109244975 doi "https://doi.org/10.1111/j.1471-4159.1980.tb11181.x" @default.
- W2109244975 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7354331" @default.
- W2109244975 hasPublicationYear "1980" @default.
- W2109244975 type Work @default.
- W2109244975 sameAs 2109244975 @default.
- W2109244975 citedByCount "43" @default.
- W2109244975 crossrefType "journal-article" @default.
- W2109244975 hasAuthorship W2109244975A5015782749 @default.
- W2109244975 hasAuthorship W2109244975A5015833771 @default.
- W2109244975 hasAuthorship W2109244975A5046924659 @default.
- W2109244975 hasAuthorship W2109244975A5051306819 @default.
- W2109244975 hasAuthorship W2109244975A5068357617 @default.
- W2109244975 hasConcept C134164806 @default.
- W2109244975 hasConcept C169760540 @default.
- W2109244975 hasConcept C181199279 @default.
- W2109244975 hasConcept C185592680 @default.
- W2109244975 hasConcept C2775858608 @default.
- W2109244975 hasConcept C2776819090 @default.
- W2109244975 hasConcept C2777331542 @default.
- W2109244975 hasConcept C2778186239 @default.
- W2109244975 hasConcept C2780115458 @default.
- W2109244975 hasConcept C43617362 @default.
- W2109244975 hasConcept C55493867 @default.
- W2109244975 hasConcept C86803240 @default.
- W2109244975 hasConcept C87644729 @default.
- W2109244975 hasConceptScore W2109244975C134164806 @default.
- W2109244975 hasConceptScore W2109244975C169760540 @default.
- W2109244975 hasConceptScore W2109244975C181199279 @default.
- W2109244975 hasConceptScore W2109244975C185592680 @default.
- W2109244975 hasConceptScore W2109244975C2775858608 @default.
- W2109244975 hasConceptScore W2109244975C2776819090 @default.
- W2109244975 hasConceptScore W2109244975C2777331542 @default.
- W2109244975 hasConceptScore W2109244975C2778186239 @default.
- W2109244975 hasConceptScore W2109244975C2780115458 @default.
- W2109244975 hasConceptScore W2109244975C43617362 @default.
- W2109244975 hasConceptScore W2109244975C55493867 @default.
- W2109244975 hasConceptScore W2109244975C86803240 @default.
- W2109244975 hasConceptScore W2109244975C87644729 @default.
- W2109244975 hasIssue "3" @default.
- W2109244975 hasLocation W21092449751 @default.
- W2109244975 hasLocation W21092449752 @default.
- W2109244975 hasOpenAccess W2109244975 @default.
- W2109244975 hasPrimaryLocation W21092449751 @default.
- W2109244975 hasRelatedWork W1725452376 @default.
- W2109244975 hasRelatedWork W1983027114 @default.
- W2109244975 hasRelatedWork W2003200312 @default.
- W2109244975 hasRelatedWork W2014292534 @default.
- W2109244975 hasRelatedWork W2053647643 @default.
- W2109244975 hasRelatedWork W2055028888 @default.
- W2109244975 hasRelatedWork W2091677032 @default.
- W2109244975 hasRelatedWork W2103344402 @default.
- W2109244975 hasRelatedWork W2109244975 @default.
- W2109244975 hasRelatedWork W2193287270 @default.