Matches in SemOpenAlex for { <https://semopenalex.org/work/W2109286057> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W2109286057 endingPage "492" @default.
- W2109286057 startingPage "488" @default.
- W2109286057 abstract "Using the NAPRTCS database from January 1987 to January 2001, we examined 2687 adolescent (age 13-17 yr) index renal transplants to analyze differences in demographic treatment, and outcomes in adolescents with FSGS compared to other renal disease. 338 (12.6%) of adolescents had a primary diagnosis of FSGS. Adolescents with FSGS were more likely to be black and less likely to receive pre-emptive transplants (p < 0.001). No differences existed in HLA matching or immunosuppression regimens. Acute tubular necrosis occurred in more FSGS adolescents compared to non-FSGS adolescents following LD (11% vs. 4.7%) or CD (25.1% vs. 17.8%) transplants (p < 0.001). There were no significant differences in acute rejection rates between adolescents with FSGS and other adolescents. Graft survival was worse for LD FSGS adolescents (6 yr, 56%) compared to non-FSGS adolescents (77%) (p < 0.001) and was not significantly different from CD graft survival in FSGS (51%) or non-FSGS groups (61%). The relative risk (RR) of graft failure was greatest in LD transplant with FSGS (RR = 1.75; p < 0.001), compared to LD transplants without FSGS (RR = 1.0). Recurrent primary disease accounted for 15.2% of all graft failures in adolescents transplanted for FSGS with no difference between LD (17%) or CD (13.8%) grafts. Recurrent disease accounted for 3.2% of graft failures in adolescents without FSGS. Recurrent disease was the only cause of graft failure that differed between groups (p < 0.001). When compared to patients up to age 12 yr with FSGS, graft survival in both LD and CD transplants was worse in adolescents with FSGS (LD p = 0.035, CD p < 0.001). In conclusion, FSGS has a negative impact on graft survival in adolescents. Recurrence of FSGS results in a loss of the expected LD graft survival advantage in adolescents. Furthermore, adolescents with FSGS have decreased graft survival compared to younger children with FSGS. These data suggest that the rationale for LD transplantation in adolescents with FSGS should be based on factors other than the increased graft survival typically seen with LD transplantation." @default.
- W2109286057 created "2016-06-24" @default.
- W2109286057 creator A5035293589 @default.
- W2109286057 creator A5044256758 @default.
- W2109286057 creator A5046105449 @default.
- W2109286057 creator A5084438049 @default.
- W2109286057 date "2002-12-01" @default.
- W2109286057 modified "2023-10-03" @default.
- W2109286057 title "Outcome of renal transplantation in adolescents with focal segmental glomerulosclerosis" @default.
- W2109286057 cites W1544293109 @default.
- W2109286057 cites W1985770728 @default.
- W2109286057 cites W1987187390 @default.
- W2109286057 cites W2006526573 @default.
- W2109286057 cites W2039080756 @default.
- W2109286057 cites W2053405208 @default.
- W2109286057 cites W2056766976 @default.
- W2109286057 cites W2057156291 @default.
- W2109286057 cites W2133088917 @default.
- W2109286057 cites W2135510331 @default.
- W2109286057 cites W2182078251 @default.
- W2109286057 cites W2412304226 @default.
- W2109286057 doi "https://doi.org/10.1034/j.1399-3046.2002.02036.x" @default.
- W2109286057 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12453201" @default.
- W2109286057 hasPublicationYear "2002" @default.
- W2109286057 type Work @default.
- W2109286057 sameAs 2109286057 @default.
- W2109286057 citedByCount "62" @default.
- W2109286057 countsByYear W21092860572012 @default.
- W2109286057 countsByYear W21092860572013 @default.
- W2109286057 countsByYear W21092860572014 @default.
- W2109286057 countsByYear W21092860572015 @default.
- W2109286057 countsByYear W21092860572016 @default.
- W2109286057 countsByYear W21092860572017 @default.
- W2109286057 countsByYear W21092860572018 @default.
- W2109286057 countsByYear W21092860572019 @default.
- W2109286057 countsByYear W21092860572020 @default.
- W2109286057 countsByYear W21092860572022 @default.
- W2109286057 countsByYear W21092860572023 @default.
- W2109286057 crossrefType "journal-article" @default.
- W2109286057 hasAuthorship W2109286057A5035293589 @default.
- W2109286057 hasAuthorship W2109286057A5044256758 @default.
- W2109286057 hasAuthorship W2109286057A5046105449 @default.
- W2109286057 hasAuthorship W2109286057A5084438049 @default.
- W2109286057 hasBestOaLocation W21092860571 @default.
- W2109286057 hasConcept C126322002 @default.
- W2109286057 hasConcept C126894567 @default.
- W2109286057 hasConcept C141071460 @default.
- W2109286057 hasConcept C187212893 @default.
- W2109286057 hasConcept C2777350860 @default.
- W2109286057 hasConcept C2778415529 @default.
- W2109286057 hasConcept C2778653478 @default.
- W2109286057 hasConcept C2779561371 @default.
- W2109286057 hasConcept C2780091579 @default.
- W2109286057 hasConcept C2780252810 @default.
- W2109286057 hasConcept C2911091166 @default.
- W2109286057 hasConcept C71924100 @default.
- W2109286057 hasConcept C90924648 @default.
- W2109286057 hasConceptScore W2109286057C126322002 @default.
- W2109286057 hasConceptScore W2109286057C126894567 @default.
- W2109286057 hasConceptScore W2109286057C141071460 @default.
- W2109286057 hasConceptScore W2109286057C187212893 @default.
- W2109286057 hasConceptScore W2109286057C2777350860 @default.
- W2109286057 hasConceptScore W2109286057C2778415529 @default.
- W2109286057 hasConceptScore W2109286057C2778653478 @default.
- W2109286057 hasConceptScore W2109286057C2779561371 @default.
- W2109286057 hasConceptScore W2109286057C2780091579 @default.
- W2109286057 hasConceptScore W2109286057C2780252810 @default.
- W2109286057 hasConceptScore W2109286057C2911091166 @default.
- W2109286057 hasConceptScore W2109286057C71924100 @default.
- W2109286057 hasConceptScore W2109286057C90924648 @default.
- W2109286057 hasIssue "6" @default.
- W2109286057 hasLocation W21092860571 @default.
- W2109286057 hasLocation W21092860572 @default.
- W2109286057 hasOpenAccess W2109286057 @default.
- W2109286057 hasPrimaryLocation W21092860571 @default.
- W2109286057 hasRelatedWork W2003938723 @default.
- W2109286057 hasRelatedWork W2019928912 @default.
- W2109286057 hasRelatedWork W2047967234 @default.
- W2109286057 hasRelatedWork W2063513203 @default.
- W2109286057 hasRelatedWork W2118496982 @default.
- W2109286057 hasRelatedWork W2328648896 @default.
- W2109286057 hasRelatedWork W2364998975 @default.
- W2109286057 hasRelatedWork W2439875401 @default.
- W2109286057 hasRelatedWork W4238867864 @default.
- W2109286057 hasRelatedWork W2525756941 @default.
- W2109286057 hasVolume "6" @default.
- W2109286057 isParatext "false" @default.
- W2109286057 isRetracted "false" @default.
- W2109286057 magId "2109286057" @default.
- W2109286057 workType "article" @default.