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• W2109290293 abstract "No AccessJournal of UrologyCLINICAL UROLOGY: Original Articles1 Sep 2001PREDICTORS OF UTILITIES FOR HEALTH STATES IN EARLY STAGE PROSTATE CANCER CHRISTOPHER S. SAIGAL, JEFFREY GORNBEIN, ROBERT NEASE, and MARK S. LITWIN CHRISTOPHER S. SAIGALCHRISTOPHER S. SAIGAL More articles by this author , JEFFREY GORNBEINJEFFREY GORNBEIN More articles by this author , ROBERT NEASEROBERT NEASE More articles by this author , and MARK S. LITWINMARK S. LITWIN More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(05)65869-7AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: When faced with treatment choices for early stage prostate cancer, patients must balance the survival benefit of a treatment with its morbidity. Little is known about how patients balance these trade-offs. To further our understanding of patient decision making we assessed patient utilities for prostate cancer treatment related morbidities. We determined whether patient utilities were predicted by sociodemographic characteristics or baseline genitourinary function. Materials and Methods: We evaluated 401 men undergoing prostate needle biopsy for suspicion of prostate cancer at university, Veterans Affairs and public hospitals. Study design included a prospective cross-sectional cohort with correlation and multivariate analysis. Subjects were studied with 2 established health related quality of life instruments. Patient utilities were assessed with an interactive software application. Results: On multivariate analysis utility for current general health was a significant predictor of utilities for treatment related morbidities. Surprisingly baseline urinary, sexual and bowel function scores did not correlate well with respective utilities for potential incontinence, impotence or radiation proctitis. In other words, men with good and imperfect baseline function were equally willing to risk impairment to preserve life. Conclusions: Men who perceived that general health was better appear to place higher value on quantity of life, while those who already are suffering from poor general health place higher value on quality of life. Ethnicity appears to modify some effects of other variables on patient preference. Utility assessment provides a quantitative tool to aid physicians in counseling patients when making treatment decisions for localized prostate cancer. References 1 : Measurement of health-related quality of life in men with prostate cancer: the CaPSURE database. Qual Life Res1997; 6: 385. Google Scholar 2 : Quality-of-life outcomes in long-term survivors of advanced prostate cancer. 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Link, Google Scholar 16 : Waning sexual function: the most important disease-specific distress for patients with prostate cancer. Br J Cancer1996; 73: 1417. Google Scholar 17 : Older patients’ willingness to trade off urologic adverse outcomes for a better chance at five-year survival in the clinical setting of prostate cancer. J Am Geriatr Soc1995; 43: 979. Google Scholar 18 : The Beaver Dam Health Outcomes Study: initial catalog of health-state quality factors. Med Decis Making1993; 13: 89. Google Scholar 19 : Health values of hospitalized patients 80 years or older. HELP Investigators. Hospitalized Elderly Longitudinal Project. JAMA1998; 279: 371. Google Scholar From the Departments of Urology, Health Services and Biomathematics, and Statistical-Biomathematical Consulting Clinic, University of California, Los Angeles, Los Angeles, California, and Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri© 2001 by American Urological Association, Inc.FiguresReferencesRelatedDetailsCited byLITWIN M, SADETSKY N, PASTA D and LUBECK D (2018) BOWEL FUNCTION AND BOTHER AFTER TREATMENT FOR EARLY STAGE PROSTATE CANCER: A LONGITUDINAL QUALITY OF LIFE ANALYSIS FROM CaPSUREJournal of Urology, VOL. 172, NO. 2, (515-519), Online publication date: 1-Aug-2004.PENSON D, LITWIN M and AARONSON N (2018) Health Related Quality of Life in Men With Prostate CancerJournal of Urology, VOL. 169, NO. 5, (1653-1661), Online publication date: 1-May-2003. Volume 166Issue 3September 2001Page: 942-946 Advertisement Copyright & Permissions© 2001 by American Urological Association, Inc.Keywordsquality of lifeprostatemorbidityprostatic neoplasmsutility theoryMetricsAuthor Information CHRISTOPHER S. SAIGAL More articles by this author JEFFREY GORNBEIN More articles by this author ROBERT NEASE More articles by this author MARK S. LITWIN More articles by this author Expand All Advertisement PDF downloadLoading ..." @default.
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