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- W2109303083 abstract "Abstract OBJECTIVE: Review the rationale behind secondary prevention of Barrett’s related esophageal adenocarcinoma and critically appraise the emerging literature regarding prevention of neoplasia in Barrett’s esophagus with antisecretory and/or cyclo-oxygenase inhibition therapy. METHODS: The existing English language literature regarding secondary cancer prevention in patients with Barrett’s esophagus is reviewed and its potential clinical implications discussed. RESULTS: There is biologic plausibility to pursue “chemoprevention” trials with antisecretory and/or cyclo-oxygenase inhibition therapy in patients with Barrett’s esophagus. CONCLUSION: Chemoprevention trials using potent antisecretory therapy coupled with cyclo-oxygenase 2 inhibition are warranted and may provide a means of decreasing the occurrence of cancer and cancer-related mortality in this disease." @default.
- W2109303083 created "2016-06-24" @default.
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- W2109303083 date "2001-08-01" @default.
- W2109303083 modified "2023-10-17" @default.
- W2109303083 title "Barrett's-related esophageal adenocarcinoma: is chemoprevention a potential option?" @default.
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- W2109303083 doi "https://doi.org/10.1016/s0002-9270(01)02596-5" @default.
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