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- W2109304619 abstract "”Blood-enriching Dang-Gui Decoction” (BDGD), comprised of Angelica sinensis (Oliv.) Diels and Astragalus membranaccus (Fisch) Bge and used for improvement health in traditional Chinese medicine, was selected for immunopharmacologica1 activity test. Effects of aqueous extracts of BDGD, A. sinensis, and A. membranaccus on human peripheral blood mononuclear cells (PBMC) proliferation were determined by tritiated thymidine uptake, respectively. Aqueous extracts from all three preparations significantly enhanced the proliferation of PBMC induced by phytohemagglutinin (PHA) with an EC50 of 106.3±5.8, 91.3±2.5, and 23.8±4.0 μg/ml, resepctively. Furthermore, all extracts dose-dependently enhanced interleukin-2 (IL-2), interleukin-3 (IL-3), and interferon-γ (IFN-γ) production in PHA-stimulated PBMC, suggesting that pharmacological activities of these drugs may be mediated by regulating the production of cytokines in PBMC. These results indicate that agents with immunomodulatory effects are contained in BDGD." @default.
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- W2109304619 date "2001-09-01" @default.
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- W2109304619 title "ENHANCEMENT OF CELL PROLIFERATION AND CYTOKINES PRODUCTION IN HUMAN PERIPHERAL BLOOD MONONUCLEAR CELLS BY EXTRACTS FROM BLOOD-ENRICHING DANG-GUI DECOCTION" @default.
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