Matches in SemOpenAlex for { <https://semopenalex.org/work/W2109306599> ?p ?o ?g. }
- W2109306599 endingPage "8719" @default.
- W2109306599 startingPage "8709" @default.
- W2109306599 abstract "There has been no unequivocal demonstration that the activator binding targets identified in vitro play a key role in transcriptional activation in vivo. To examine whether activator-Mediator interactions are required for gene transcription under physiological conditions, we performed functional analyses with Mediator components that interact specifically with natural yeast activators. Different activators interact with Mediator via distinct binding targets. Deletion of a distinct activator binding region of Mediator completely compromised gene activation in vivo by some, but not all, transcriptional activators. These demonstrate that the activator-specific targets in Mediator are essential for transcriptional activation in living cells, but their requirement was affected by the nature of the activator-DNA interaction and the existence of a postrecruitment activation process." @default.
- W2109306599 created "2016-06-24" @default.
- W2109306599 creator A5030581323 @default.
- W2109306599 creator A5032758601 @default.
- W2109306599 creator A5037534545 @default.
- W2109306599 creator A5051652536 @default.
- W2109306599 creator A5055732872 @default.
- W2109306599 creator A5077721033 @default.
- W2109306599 date "2000-12-01" @default.
- W2109306599 modified "2023-10-16" @default.
- W2109306599 title "In Vivo Requirement of Activator-Specific Binding Targets of Mediator" @default.
- W2109306599 cites W1566478858 @default.
- W2109306599 cites W1659534939 @default.
- W2109306599 cites W1808467244 @default.
- W2109306599 cites W1826828186 @default.
- W2109306599 cites W1867089556 @default.
- W2109306599 cites W1881561702 @default.
- W2109306599 cites W1965652496 @default.
- W2109306599 cites W1979647722 @default.
- W2109306599 cites W1992338259 @default.
- W2109306599 cites W1992670664 @default.
- W2109306599 cites W2009523975 @default.
- W2109306599 cites W2013241678 @default.
- W2109306599 cites W2018966815 @default.
- W2109306599 cites W2023893656 @default.
- W2109306599 cites W2024095538 @default.
- W2109306599 cites W2026238009 @default.
- W2109306599 cites W2033983825 @default.
- W2109306599 cites W2036347938 @default.
- W2109306599 cites W2038656065 @default.
- W2109306599 cites W2040249554 @default.
- W2109306599 cites W2047723385 @default.
- W2109306599 cites W2054396191 @default.
- W2109306599 cites W2062439115 @default.
- W2109306599 cites W2062796383 @default.
- W2109306599 cites W2071984843 @default.
- W2109306599 cites W2072093173 @default.
- W2109306599 cites W2096917096 @default.
- W2109306599 cites W2098919421 @default.
- W2109306599 cites W2102514436 @default.
- W2109306599 cites W2114694204 @default.
- W2109306599 cites W2122366486 @default.
- W2109306599 cites W2127533921 @default.
- W2109306599 cites W2130749378 @default.
- W2109306599 cites W2140710406 @default.
- W2109306599 cites W2149920358 @default.
- W2109306599 cites W2155157043 @default.
- W2109306599 cites W2160947703 @default.
- W2109306599 cites W2164154631 @default.
- W2109306599 cites W2165062466 @default.
- W2109306599 cites W2169333620 @default.
- W2109306599 cites W2275861305 @default.
- W2109306599 cites W4232123327 @default.
- W2109306599 cites W4239029175 @default.
- W2109306599 cites W4242866406 @default.
- W2109306599 cites W4254483562 @default.
- W2109306599 doi "https://doi.org/10.1128/mcb.20.23.8709-8719.2000" @default.
- W2109306599 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/86488" @default.
- W2109306599 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11073972" @default.
- W2109306599 hasPublicationYear "2000" @default.
- W2109306599 type Work @default.
- W2109306599 sameAs 2109306599 @default.
- W2109306599 citedByCount "119" @default.
- W2109306599 countsByYear W21093065992012 @default.
- W2109306599 countsByYear W21093065992013 @default.
- W2109306599 countsByYear W21093065992014 @default.
- W2109306599 countsByYear W21093065992015 @default.
- W2109306599 countsByYear W21093065992016 @default.
- W2109306599 countsByYear W21093065992017 @default.
- W2109306599 countsByYear W21093065992018 @default.
- W2109306599 countsByYear W21093065992019 @default.
- W2109306599 countsByYear W21093065992020 @default.
- W2109306599 countsByYear W21093065992021 @default.
- W2109306599 countsByYear W21093065992022 @default.
- W2109306599 crossrefType "journal-article" @default.
- W2109306599 hasAuthorship W2109306599A5030581323 @default.
- W2109306599 hasAuthorship W2109306599A5032758601 @default.
- W2109306599 hasAuthorship W2109306599A5037534545 @default.
- W2109306599 hasAuthorship W2109306599A5051652536 @default.
- W2109306599 hasAuthorship W2109306599A5055732872 @default.
- W2109306599 hasAuthorship W2109306599A5077721033 @default.
- W2109306599 hasBestOaLocation W21093065992 @default.
- W2109306599 hasConcept C104317684 @default.
- W2109306599 hasConcept C138885662 @default.
- W2109306599 hasConcept C179926584 @default.
- W2109306599 hasConcept C207001950 @default.
- W2109306599 hasConcept C2107291 @default.
- W2109306599 hasConcept C41895202 @default.
- W2109306599 hasConcept C51639874 @default.
- W2109306599 hasConcept C54355233 @default.
- W2109306599 hasConcept C86339819 @default.
- W2109306599 hasConcept C86803240 @default.
- W2109306599 hasConcept C88045685 @default.
- W2109306599 hasConcept C95444343 @default.
- W2109306599 hasConceptScore W2109306599C104317684 @default.
- W2109306599 hasConceptScore W2109306599C138885662 @default.
- W2109306599 hasConceptScore W2109306599C179926584 @default.
- W2109306599 hasConceptScore W2109306599C207001950 @default.